126 related articles for article (PubMed ID: 36096200)
1. Pyrvinium doubles against WNT-driven cancer.
Fan J; Reid RR; He TC
J Biol Chem; 2022 Oct; 298(10):102479. PubMed ID: 36096200
[TBL] [Abstract][Full Text] [Related]
2. The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon.
Shen C; Nayak A; Neitzel LR; Yang F; Li B; Williams CH; Hong CC; Ahmed Y; Lee E; Robbins DJ
J Biol Chem; 2022 Aug; 298(8):102227. PubMed ID: 35780831
[TBL] [Abstract][Full Text] [Related]
3. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Thorne CA; Hanson AJ; Schneider J; Tahinci E; Orton D; Cselenyi CS; Jernigan KK; Meyers KC; Hang BI; Waterson AG; Kim K; Melancon B; Ghidu VP; Sulikowski GA; LaFleur B; Salic A; Lee LA; Miller DM; Lee E
Nat Chem Biol; 2010 Nov; 6(11):829-36. PubMed ID: 20890287
[TBL] [Abstract][Full Text] [Related]
4. The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (
Shen C; Li B; Astudillo L; Deutscher MP; Cobb MH; Capobianco AJ; Lee E; Robbins DJ
Biochemistry; 2019 Dec; 58(51):5102-5106. PubMed ID: 31820934
[TBL] [Abstract][Full Text] [Related]
5. Pyrvinium Sensitizes Clear Cell Renal Cell Carcinoma Response to Chemotherapy Via Casein Kinase 1α-Dependent Inhibition of Wnt/β-Catenin.
Cui L; Zhao J; Liu J
Am J Med Sci; 2018 Mar; 355(3):274-280. PubMed ID: 29549930
[TBL] [Abstract][Full Text] [Related]
6. Targeting of Wnt/β-Catenin by Anthelmintic Drug Pyrvinium Enhances Sensitivity of Ovarian Cancer Cells to Chemotherapy.
Zhang C; Zhang Z; Zhang S; Wang W; Hu P
Med Sci Monit; 2017 Jan; 23():266-275. PubMed ID: 28090074
[TBL] [Abstract][Full Text] [Related]
7. Inhibitory effect of pyrvinium pamoate on uveal melanoma cells involves blocking of Wnt/β-catenin pathway.
Zheng L; Liu Y; Pan J
Acta Biochim Biophys Sin (Shanghai); 2017 Oct; 49(10):890-898. PubMed ID: 28981601
[TBL] [Abstract][Full Text] [Related]
8. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
Li B; Orton D; Neitzel LR; Astudillo L; Shen C; Long J; Chen X; Kirkbride KC; Doundoulakis T; Guerra ML; Zaias J; Fei DL; Rodriguez-Blanco J; Thorne C; Wang Z; Jin K; Nguyen DM; Sands LR; Marchetti F; Abreu MT; Cobb MH; Capobianco AJ; Lee E; Robbins DJ
Sci Signal; 2017 Jun; 10(485):. PubMed ID: 28655862
[TBL] [Abstract][Full Text] [Related]
9. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.
Saraswati S; Alfaro MP; Thorne CA; Atkinson J; Lee E; Young PP
PLoS One; 2010 Nov; 5(11):e15521. PubMed ID: 21170416
[TBL] [Abstract][Full Text] [Related]
10. MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling.
Huang Q; Chen L; Schonbrunn E; Chen J
EMBO J; 2020 Jul; 39(14):e104410. PubMed ID: 32511789
[TBL] [Abstract][Full Text] [Related]
11. Ricinine: a pyridone alkaloid from Ricinus communis that activates the Wnt signaling pathway through casein kinase 1α.
Ohishi K; Toume K; Arai MA; Sadhu SK; Ahmed F; Mizoguchi T; Itoh M; Ishibashi M
Bioorg Med Chem; 2014 Sep; 22(17):4597-601. PubMed ID: 25124862
[TBL] [Abstract][Full Text] [Related]
12. Casein kinase 1 α phosphorylates the Wnt regulator Jade-1 and modulates its activity.
Borgal L; Rinschen MM; Dafinger C; Hoff S; Reinert MJ; Lamkemeyer T; Lienkamp SS; Benzing T; Schermer B
J Biol Chem; 2014 Sep; 289(38):26344-26356. PubMed ID: 25100726
[TBL] [Abstract][Full Text] [Related]
13. Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.
Li B; Flaveny CA; Giambelli C; Fei DL; Han L; Hang BI; Bai F; Pei XH; Nose V; Burlingame O; Capobianco AJ; Orton D; Lee E; Robbins DJ
PLoS One; 2014; 9(7):e101969. PubMed ID: 25003333
[TBL] [Abstract][Full Text] [Related]
14. The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C; Nayak A; Neitzel LR; Adams AA; Silver-Isenstadt M; Sawyer LM; Benchabane H; Wang H; Bunnag N; Li B; Wynn DT; Yang F; Garcia-Contreras M; Williams CH; Dakshanamurthy S; Hong CC; Ayad NG; Capobianco AJ; Ahmed Y; Lee E; Robbins DJ
Nat Commun; 2021 Sep; 12(1):5263. PubMed ID: 34489457
[TBL] [Abstract][Full Text] [Related]
15. Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis.
Sinnberg T; Menzel M; Kaesler S; Biedermann T; Sauer B; Nahnsen S; Schwarz M; Garbe C; Schittek B
Cancer Res; 2010 Sep; 70(17):6999-7009. PubMed ID: 20699366
[TBL] [Abstract][Full Text] [Related]
16. Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation.
Li H; Jeong JH; Kwon SW; Lee SK; Lee HJ; Ryu JH
Molecules; 2020 Feb; 25(3):. PubMed ID: 32041324
[TBL] [Abstract][Full Text] [Related]
17. Distinctive microRNA signature associated of neoplasms with the Wnt/β-catenin signaling pathway.
Sun X; He Y; Huang C; Ma TT; Li J
Cell Signal; 2013 Dec; 25(12):2805-11. PubMed ID: 24041653
[TBL] [Abstract][Full Text] [Related]
18. Pyrvinium pamoate attenuates non-alcoholic steatohepatitis: Insight on hedgehog/Gli and Wnt/β-catenin signaling crosstalk.
El-Derany MO; El-Demerdash E
Biochem Pharmacol; 2020 Jul; 177():113942. PubMed ID: 32240652
[TBL] [Abstract][Full Text] [Related]
19. Possible repurposing of pyrvinium pamoate for the treatment of mesothelioma: A pre-clinical assessment.
Barbarino M; Cesari D; Intruglio R; Indovina P; Namagerdi A; Bertolino FM; Bottaro M; Rahmani D; Bellan C; Giordano A
J Cell Physiol; 2018 Sep; 233(9):7391-7401. PubMed ID: 29659015
[TBL] [Abstract][Full Text] [Related]
20. Pyrvinium pamoate ameliorates cyclosporin A- induced hepatotoxicity via the modulation of Wnt/β-catenin signaling and upregulation of PPAR-γ.
Faheem SA; El-Sayed NM; Moustafa YM; Saeed NM; Hazem RM
Int Immunopharmacol; 2022 Mar; 104():108538. PubMed ID: 35074592
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]