169 related articles for article (PubMed ID: 36111834)
1. Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses.
Drewry DH; Potjewyd FM; Bayati A; Smith JL; Dickmander RJ; Howell S; Taft-Benz S; Min SM; Hossain MA; Heise M; McPherson PS; Moorman NJ; Axtman AD
J Med Chem; 2022 Oct; 65(19):12860-12882. PubMed ID: 36111834
[TBL] [Abstract][Full Text] [Related]
2. The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.
Dayam RM; Sun CX; Choy CH; Mancuso G; Glogauer M; Botelho RJ
J Immunol; 2017 Sep; 199(6):2096-2105. PubMed ID: 28779020
[TBL] [Abstract][Full Text] [Related]
3. YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.
Ikonomov OC; Sbrissa D; Shisheva A
Biochem Biophys Res Commun; 2009 May; 382(3):566-70. PubMed ID: 19289105
[TBL] [Abstract][Full Text] [Related]
4. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
Sbrissa D; Ikonomov OC; Filios C; Delvecchio K; Shisheva A
Am J Physiol Cell Physiol; 2012 Aug; 303(4):C436-46. PubMed ID: 22621786
[TBL] [Abstract][Full Text] [Related]
5. The PIKfyve Inhibitor Apilimod: A Double-Edged Sword against COVID-19.
Baranov MV; Bianchi F; van den Bogaart G
Cells; 2020 Dec; 10(1):. PubMed ID: 33375410
[TBL] [Abstract][Full Text] [Related]
6. Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2.
Davis-Gilbert ZW; Krämer A; Dunford JE; Howell S; Senbabaoglu F; Wells CI; Bashore FM; Havener TM; Smith JL; Hossain MA; Oppermann U; Drewry DH; Axtman AD
ACS Med Chem Lett; 2023 Apr; 14(4):432-441. PubMed ID: 37077385
[TBL] [Abstract][Full Text] [Related]
7. Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.
Gayle S; Landrette S; Beeharry N; Conrad C; Hernandez M; Beckett P; Ferguson SM; Mandelkern T; Zheng M; Xu T; Rothberg J; Lichenstein H
Blood; 2017 Mar; 129(13):1768-1778. PubMed ID: 28104689
[TBL] [Abstract][Full Text] [Related]
8. Development of Three Orthogonal Assays Suitable for the Identification and Qualification of PIKfyve Inhibitors.
Fogarty K; Kashem M; Bauer A; Bernardino A; Brennan D; Cook B; Farrow N; Molinaro T; Nelson R
Assay Drug Dev Technol; 2017 Jul; 15(5):210-219. PubMed ID: 28723271
[TBL] [Abstract][Full Text] [Related]
9. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
Sharma G; Guardia CM; Roy A; Vassilev A; Saric A; Griner LN; Marugan J; Ferrer M; Bonifacino JS; DePamphilis ML
Autophagy; 2019 Oct; 15(10):1694-1718. PubMed ID: 30806145
[TBL] [Abstract][Full Text] [Related]
10. PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation.
Sbrissa D; Ikonomov OC; Shisheva A
Biochemistry; 2000 Dec; 39(51):15980-9. PubMed ID: 11123925
[TBL] [Abstract][Full Text] [Related]
11. Identification of PIKfyve kinase as a target in multiple myeloma.
de Campos CB; Zhu YX; Sepetov N; Romanov S; Bruins LA; Shi CX; Stein CK; Petit JL; Polito AN; Sharik ME; Meermeier EW; Ahmann GJ; Armenta IDL; Kruse J; Bergsagel PL; Chesi M; Meurice N; Braggio E; Stewart AK
Haematologica; 2020 Jun; 105(6):1641-1649. PubMed ID: 31582538
[TBL] [Abstract][Full Text] [Related]
12. PIKfyve negatively regulates exocytosis in neurosecretory cells.
Osborne SL; Wen PJ; Boucheron C; Nguyen HN; Hayakawa M; Kaizawa H; Parker PJ; Vitale N; Meunier FA
J Biol Chem; 2008 Feb; 283(5):2804-13. PubMed ID: 18039667
[TBL] [Abstract][Full Text] [Related]
13. Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Giridharan SSP; Luo G; Rivero-Rios P; Steinfeld N; Tronchere H; Singla A; Burstein E; Billadeau DD; Sutton MA; Weisman LS
Elife; 2022 Jan; 11():. PubMed ID: 35040777
[TBL] [Abstract][Full Text] [Related]
14. PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling.
Cai X; Xu Y; Cheung AK; Tomlinson RC; Alcázar-Román A; Murphy L; Billich A; Zhang B; Feng Y; Klumpp M; Rondeau JM; Fazal AN; Wilson CJ; Myer V; Joberty G; Bouwmeester T; Labow MA; Finan PM; Porter JA; Ploegh HL; Baird D; De Camilli P; Tallarico JA; Huang Q
Chem Biol; 2013 Jul; 20(7):912-21. PubMed ID: 23890009
[TBL] [Abstract][Full Text] [Related]
15. Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.
Ikonomov OC; Sbrissa D; Mlak K; Kanzaki M; Pessin J; Shisheva A
J Biol Chem; 2002 Mar; 277(11):9206-11. PubMed ID: 11714711
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.
Saffi GT; Wang CA; Mangialardi EM; Vacher J; Botelho RJ; Salmena L
J Biol Chem; 2022 Aug; 298(8):102187. PubMed ID: 35760104
[TBL] [Abstract][Full Text] [Related]
17. In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.
Zolov SN; Bridges D; Zhang Y; Lee WW; Riehle E; Verma R; Lenk GM; Converso-Baran K; Weide T; Albin RL; Saltiel AR; Meisler MH; Russell MW; Weisman LS
Proc Natl Acad Sci U S A; 2012 Oct; 109(43):17472-7. PubMed ID: 23047693
[TBL] [Abstract][Full Text] [Related]
18. Insights into Lysosomal PI(3,5)P
Lees JA; Li P; Kumar N; Weisman LS; Reinisch KM
Mol Cell; 2020 Nov; 80(4):736-743.e4. PubMed ID: 33098764
[TBL] [Abstract][Full Text] [Related]
19. Rational Design and Synthesis of D-galactosyl Lysophospholipids as Selective Substrates and non-ATP-competitive Inhibitors of Phosphatidylinositol Phosphate Kinases.
Sun M; Zhang C; Sui D; Yang C; Pyeon D; Huang X; Hu J
Chemistry; 2023 Jan; 29(2):e202202083. PubMed ID: 36424188
[TBL] [Abstract][Full Text] [Related]
20. The amyloid precursor protein (APP) binds the PIKfyve complex and modulates its function.
Currinn H; Wassmer T
Biochem Soc Trans; 2016 Feb; 44(1):185-90. PubMed ID: 26862204
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
