191 related articles for article (PubMed ID: 36115594)
1. 1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells.
Cordes T; Kuna RS; McGregor GH; Khare SV; Gengatharan J; Muthusamy T; Metallo CM
J Lipid Res; 2022 Oct; 63(10):100281. PubMed ID: 36115594
[TBL] [Abstract][Full Text] [Related]
2. Serine restriction alters sphingolipid diversity to constrain tumour growth.
Muthusamy T; Cordes T; Handzlik MK; You L; Lim EW; Gengatharan J; Pinto AFM; Badur MG; Kolar MJ; Wallace M; Saghatelian A; Metallo CM
Nature; 2020 Oct; 586(7831):790-795. PubMed ID: 32788725
[TBL] [Abstract][Full Text] [Related]
3. Tsc3 regulates SPT amino acid choice in
Ren J; Saied EM; Zhong A; Snider J; Ruiz C; Arenz C; Obeid LM; Girnun GD; Hannun YA
J Lipid Res; 2018 Nov; 59(11):2126-2139. PubMed ID: 30154231
[TBL] [Abstract][Full Text] [Related]
4. Role of 1-Deoxysphingolipids in docetaxel neurotoxicity.
Becker KA; Uerschels AK; Goins L; Doolen S; McQuerry KJ; Bielawski J; Sure U; Bieberich E; Taylor BK; Gulbins E; Spassieva SD
J Neurochem; 2020 Sep; 154(6):662-672. PubMed ID: 32058598
[TBL] [Abstract][Full Text] [Related]
5. HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship.
Bode H; Bourquin F; Suriyanarayanan S; Wei Y; Alecu I; Othman A; Von Eckardstein A; Hornemann T
Hum Mol Genet; 2016 Mar; 25(5):853-65. PubMed ID: 26681808
[TBL] [Abstract][Full Text] [Related]
6. SPTLC1 variants associated with ALS produce distinct sphingolipid signatures through impaired interaction with ORMDL proteins.
Lone MA; Aaltonen MJ; Zidell A; Pedro HF; Morales Saute JA; Mathew S; Mohassel P; Bönnemann CG; Shoubridge EA; Hornemann T
J Clin Invest; 2022 Sep; 132(18):. PubMed ID: 35900868
[TBL] [Abstract][Full Text] [Related]
7. Novel HSAN1 mutation in serine palmitoyltransferase resides at a putative phosphorylation site that is involved in regulating substrate specificity.
Ernst D; Murphy SM; Sathiyanadan K; Wei Y; Othman A; Laurá M; Liu YT; Penno A; Blake J; Donaghy M; Houlden H; Reilly MM; Hornemann T
Neuromolecular Med; 2015 Mar; 17(1):47-57. PubMed ID: 25567748
[TBL] [Abstract][Full Text] [Related]
8. Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia.
Jun BK; Chandra A; Kuljis D; Schmidt BP; Eichler FS
J Neurosci; 2015 Oct; 35(40):13713-9. PubMed ID: 26446223
[TBL] [Abstract][Full Text] [Related]
9. Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients: A novel approach for treating diabetic neuropathy?
Othman A; Benghozi R; Alecu I; Wei Y; Niesor E; von Eckardstein A; Hornemann T
J Clin Lipidol; 2015; 9(4):568-75. PubMed ID: 26228675
[TBL] [Abstract][Full Text] [Related]
10. Disturbed sphingolipid metabolism with elevated 1-deoxysphingolipids in glycogen storage disease type I - A link to metabolic control.
Hornemann T; Alecu I; Hagenbuch N; Zhakupova A; Cremonesi A; Gautschi M; Jung HH; Meienberg F; Bilz S; Christ E; Baumgartner MR; Hochuli M
Mol Genet Metab; 2018 Sep; 125(1-2):73-78. PubMed ID: 30037504
[TBL] [Abstract][Full Text] [Related]
11. 1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma.
Duan J; Merrill AH
J Biol Chem; 2015 Jun; 290(25):15380-15389. PubMed ID: 25947379
[TBL] [Abstract][Full Text] [Related]
12. A disease-causing mutation in the active site of serine palmitoyltransferase causes catalytic promiscuity.
Gable K; Gupta SD; Han G; Niranjanakumari S; Harmon JM; Dunn TM
J Biol Chem; 2010 Jul; 285(30):22846-52. PubMed ID: 20504773
[TBL] [Abstract][Full Text] [Related]
13. Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.
Garofalo K; Penno A; Schmidt BP; Lee HJ; Frosch MP; von Eckardstein A; Brown RH; Hornemann T; Eichler FS
J Clin Invest; 2011 Dec; 121(12):4735-45. PubMed ID: 22045570
[TBL] [Abstract][Full Text] [Related]
14. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway.
Alecu I; Othman A; Penno A; Saied EM; Arenz C; von Eckardstein A; Hornemann T
J Lipid Res; 2017 Jan; 58(1):60-71. PubMed ID: 27872144
[TBL] [Abstract][Full Text] [Related]
15. Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.
Gantner ML; Eade K; Wallace M; Handzlik MK; Fallon R; Trombley J; Bonelli R; Giles S; Harkins-Perry S; Heeren TFC; Sauer L; Ideguchi Y; Baldini M; Scheppke L; Dorrell MI; Kitano M; Hart BJ; Cai C; Nagasaki T; Badur MG; Okada M; Woods SM; Egan C; Gillies M; Guymer R; Eichler F; Bahlo M; Fruttiger M; Allikmets R; Bernstein PS; Metallo CM; Friedlander M
N Engl J Med; 2019 Oct; 381(15):1422-1433. PubMed ID: 31509666
[TBL] [Abstract][Full Text] [Related]
16. A Novel Variant (Asn177Asp) in SPTLC2 Causing Hereditary Sensory Autonomic Neuropathy Type 1C.
Suriyanarayanan S; Othman A; Dräger B; Schirmacher A; Young P; Mulahasanovic L; Hörtnagel K; Biskup S; von Eckardstein A; Hornemann T; Lone MA
Neuromolecular Med; 2019 Jun; 21(2):182-191. PubMed ID: 30955194
[TBL] [Abstract][Full Text] [Related]
17. Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum.
Ikushiro H; Murakami T; Takahashi A; Katayama A; Sawai T; Goto H; Koolath S; Murai Y; Monde K; Miyahara I; Kamiya N; Yano T
J Biol Chem; 2023 May; 299(5):104684. PubMed ID: 37030501
[TBL] [Abstract][Full Text] [Related]
18. The ORMDL/Orm-serine palmitoyltransferase (SPT) complex is directly regulated by ceramide: Reconstitution of SPT regulation in isolated membranes.
Davis DL; Gable K; Suemitsu J; Dunn TM; Wattenberg BW
J Biol Chem; 2019 Mar; 294(13):5146-5156. PubMed ID: 30700557
[TBL] [Abstract][Full Text] [Related]
19. Serine Palmitoyltransferase Subunit 3 and Metabolic Diseases.
Lone MA; Bourquin F; Hornemann T
Adv Exp Med Biol; 2022; 1372():47-56. PubMed ID: 35503173
[TBL] [Abstract][Full Text] [Related]
20. Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases.
Lone MA; Hülsmeier AJ; Saied EM; Karsai G; Arenz C; von Eckardstein A; Hornemann T
Proc Natl Acad Sci U S A; 2020 Jul; 117(27):15591-15598. PubMed ID: 32576697
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
