These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. Uranbileg B; Ikeda H; Kurano M; Enooku K; Sato M; Saigusa D; Aoki J; Ishizawa T; Hasegawa K; Kokudo N; Yatomi Y PLoS One; 2016; 11(2):e0149462. PubMed ID: 26886371 [TBL] [Abstract][Full Text] [Related]
3. Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. Degagné E; Pandurangan A; Bandhuvula P; Kumar A; Eltanawy A; Zhang M; Yoshinaga Y; Nefedov M; de Jong PJ; Fong LG; Young SG; Bittman R; Ahmedi Y; Saba JD J Clin Invest; 2014 Dec; 124(12):5368-84. PubMed ID: 25347472 [TBL] [Abstract][Full Text] [Related]
4. Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P Uranbileg B; Nishikawa T; Ikeda H; Kurano M; Sato M; Saigusa D; Aoki J; Watanabe T; Yatomi Y Clin Colorectal Cancer; 2018 Jun; 17(2):e171-e182. PubMed ID: 29223361 [TBL] [Abstract][Full Text] [Related]
6. Sphingosine 1-phosphate is a key metabolite linking sphingolipids to glycerophospholipids. Kihara A Biochim Biophys Acta; 2014 May; 1841(5):766-72. PubMed ID: 23994042 [TBL] [Abstract][Full Text] [Related]
7. Sphingolipid-to-glycerophospholipid conversion in SPL-null cells implies the existence of an alternative isozyme. Ikeda M; Kihara A; Kariya Y; Lee YM; Igarashi Y Biochem Biophys Res Commun; 2005 Apr; 329(2):474-9. PubMed ID: 15737611 [TBL] [Abstract][Full Text] [Related]
8. Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer. Oskouian B; Sooriyakumaran P; Borowsky AD; Crans A; Dillard-Telm L; Tam YY; Bandhuvula P; Saba JD Proc Natl Acad Sci U S A; 2006 Nov; 103(46):17384-9. PubMed ID: 17090686 [TBL] [Abstract][Full Text] [Related]
9. Sphingosine-1 Phosphate Lyase Regulates Sensitivity of Pancreatic Beta-Cells to Lipotoxicity. Tang Y; Plötz T; Gräler MH; Gurgul-Convey E Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639233 [TBL] [Abstract][Full Text] [Related]
10. Recent Insight into the Role of Sphingosine-1-Phosphate Lyase in Neurodegeneration. Wieczorek I; Strosznajder RP Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047151 [TBL] [Abstract][Full Text] [Related]
12. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Bourquin F; Riezman H; Capitani G; Grütter MG Structure; 2010 Aug; 18(8):1054-65. PubMed ID: 20696404 [TBL] [Abstract][Full Text] [Related]
13. First evidence of sphingosine 1-phosphate lyase protein expression and activity downregulation in human neoplasm: implication for resistance to therapeutics in prostate cancer. Brizuela L; Ader I; Mazerolles C; Bocquet M; Malavaud B; Cuvillier O Mol Cancer Ther; 2012 Sep; 11(9):1841-51. PubMed ID: 22784711 [TBL] [Abstract][Full Text] [Related]