148 related articles for article (PubMed ID: 36126388)
1. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead.
Grabrijan K; Hrast M; Proj M; Dolšak A; Zdovc I; Imre T; Petri L; Ábrányi-Balogh P; Keserű GM; Gobec S
Eur J Med Chem; 2022 Dec; 243():114752. PubMed ID: 36126388
[TBL] [Abstract][Full Text] [Related]
2. Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Skarzynski T; Mistry A; Wonacott A; Hutchinson SE; Kelly VA; Duncan K
Structure; 1996 Dec; 4(12):1465-74. PubMed ID: 8994972
[TBL] [Abstract][Full Text] [Related]
3. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release.
Eschenburg S; Priestman M; Schönbrunn E
J Biol Chem; 2005 Feb; 280(5):3757-63. PubMed ID: 15531591
[TBL] [Abstract][Full Text] [Related]
4. In vitro and in vivo functional activity of Chlamydia MurA, a UDP-N-acetylglucosamine enolpyruvyl transferase involved in peptidoglycan synthesis and fosfomycin resistance.
McCoy AJ; Sandlin RC; Maurelli AT
J Bacteriol; 2003 Feb; 185(4):1218-28. PubMed ID: 12562791
[TBL] [Abstract][Full Text] [Related]
5. Advances in UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Covalent Inhibition.
de Oliveira MVD; Furtado RM; da Costa KS; Vakal S; Lima AH
Front Mol Biosci; 2022; 9():889825. PubMed ID: 35936791
[TBL] [Abstract][Full Text] [Related]
6. Investigation of New Inhibitors of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) by Virtual Screening with Antibacterial Assessment.
Boulhissa I; Chikhi A; Bensegueni A; Ghattas MA; Mokrani EH; Alrawashdeh S; Obaid DEE
Curr Comput Aided Drug Des; 2021; 17(2):214-224. PubMed ID: 32053077
[TBL] [Abstract][Full Text] [Related]
7. Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Bensen DC; Rodriguez S; Nix J; Cunningham ML; Tari LW
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Apr; 68(Pt 4):382-5. PubMed ID: 22505403
[TBL] [Abstract][Full Text] [Related]
8. Bromo-Cyclobutenaminones as New Covalent UDP-
Hamilton DJ; Ábrányi-Balogh P; Keeley A; Petri L; Hrast M; Imre T; Wijtmans M; Gobec S; Esch IJP; Keserű GM
Pharmaceuticals (Basel); 2020 Nov; 13(11):. PubMed ID: 33153141
[TBL] [Abstract][Full Text] [Related]
9. Boswellic acids, as novel inhibitor targeting peptidoglycan biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) in Escherichia coli.
Raina D; Khan FG; Tiwari H; Sangwan PL; Nargotra A; Kumar V; Khan IA; Saran S
Arch Microbiol; 2022 Jul; 204(8):472. PubMed ID: 35819545
[TBL] [Abstract][Full Text] [Related]
10. Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.
Kim DH; Lees WJ; Kempsell KE; Lane WS; Duncan K; Walsh CT
Biochemistry; 1996 Apr; 35(15):4923-8. PubMed ID: 8664284
[TBL] [Abstract][Full Text] [Related]
11. Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity.
Wagdy RA; Abutaleb NS; Fathalla RK; Elgammal Y; Weck S; Pal R; Fischer PD; Ducho C; Abadi AH; N Seleem M; Engel M; Abdel-Halim M
Eur J Med Chem; 2023 Dec; 261():115789. PubMed ID: 37717380
[TBL] [Abstract][Full Text] [Related]
12. Identification and characterization of new inhibitors of the Escherichia coli MurA enzyme.
Baum EZ; Montenegro DA; Licata L; Turchi I; Webb GC; Foleno BD; Bush K
Antimicrob Agents Chemother; 2001 Nov; 45(11):3182-8. PubMed ID: 11600375
[TBL] [Abstract][Full Text] [Related]
13. Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA.
Fathalla RK; Fröhner W; Bader CD; Fischer PD; Dahlem C; Chatterjee D; Mathea S; Kiemer AK; Arthanari H; Müller R; Abdel-Halim M; Ducho C; Engel M
J Med Chem; 2022 Nov; 65(21):14740-14763. PubMed ID: 36269107
[TBL] [Abstract][Full Text] [Related]
14. Identification of novel irreversible inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from Haemophilus influenzae.
Han SG; Lee WK; Jin BS; Lee KI; Lee HH; Yu YG
J Microbiol Biotechnol; 2013 Mar; 23(3):329-34. PubMed ID: 23462005
[TBL] [Abstract][Full Text] [Related]
15. A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA).
Eschenburg S; Priestman MA; Abdul-Latif FA; Delachaume C; Fassy F; Schönbrunn E
J Biol Chem; 2005 Apr; 280(14):14070-5. PubMed ID: 15701635
[TBL] [Abstract][Full Text] [Related]
16. Identification of a novel UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from Vibrio fischeri that confers high fosfomycin resistance in Escherichia coli.
Kumar S; Parvathi A; Hernandez RL; Cadle KM; Varela MF
Arch Microbiol; 2009 May; 191(5):425-9. PubMed ID: 19277606
[TBL] [Abstract][Full Text] [Related]
17. Screening of compound library identifies novel inhibitors against the MurA enzyme of Escherichia coli.
Raina D; Tiwari H; Sharma S; Deepika ; Chinthakindi PK; Nargotra A; Sangwan PL; Eniyan K; Bajpai U; Vishwakarma RA; Khan FG; Saran S; Khan IA
Appl Microbiol Biotechnol; 2021 May; 105(9):3611-3623. PubMed ID: 33860835
[TBL] [Abstract][Full Text] [Related]
18. Lysine 22 in UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae is crucial for enzymatic activity and the formation of covalent adducts with the substrate phosphoenolpyruvate and the antibiotic fosfomycin.
Samland AK; Amrhein N; Macheroux P
Biochemistry; 1999 Oct; 38(40):13162-9. PubMed ID: 10529188
[TBL] [Abstract][Full Text] [Related]
19. The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
Han H; Yang Y; Olesen SH; Becker A; Betzi S; Schönbrunn E
Biochemistry; 2010 May; 49(19):4276-82. PubMed ID: 20392080
[TBL] [Abstract][Full Text] [Related]
20. Catalytic Mechanism and Covalent Inhibition of UDP-
Mihalovits LM; Ferenczy GG; Keserű GM
J Chem Inf Model; 2019 Dec; 59(12):5161-5173. PubMed ID: 31715096
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
