BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 36134475)

  • 21. Pivotal role of dihydroorotate dehydrogenase as a therapeutic target in adult T-cell leukemia.
    Ishikawa C; Mori N
    Eur J Haematol; 2024 Jul; 113(1):99-109. PubMed ID: 38558052
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Dihydroorotate dehydrogenase: A drug target for the development of antimalarials.
    Singh A; Maqbool M; Mobashir M; Hoda N
    Eur J Med Chem; 2017 Jan; 125():640-651. PubMed ID: 27721149
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro.
    Kim YJ; Cubitt B; Cai Y; Kuhn JH; Vitt D; Kohlhof H; de la Torre JC
    Viruses; 2020 Jul; 12(8):. PubMed ID: 32751087
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode.
    Zeng T; Zuo Z; Luo Y; Zhao Y; Yu Y; Chen Q
    FEBS Open Bio; 2019 Aug; 9(8):1348-1354. PubMed ID: 31087527
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH).
    Munier-Lehmann H; Lucas-Hourani M; Guillou S; Helynck O; Zanghi G; Noel A; Tangy F; Vidalain PO; Janin YL
    J Med Chem; 2015 Jan; 58(2):860-77. PubMed ID: 25558988
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of Nanomolar Inhibitors for Human Dihydroorotate Dehydrogenase Using Structure-Based Drug Discovery Methods.
    Higgins WT; Vibhute S; Bennett C; Lindert S
    J Chem Inf Model; 2024 Jan; 64(2):435-448. PubMed ID: 38175956
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Dihydroorotate dehydrogenase in oxidative phosphorylation and cancer.
    Boukalova S; Hubackova S; Milosevic M; Ezrova Z; Neuzil J; Rohlena J
    Biochim Biophys Acta Mol Basis Dis; 2020 Jun; 1866(6):165759. PubMed ID: 32151633
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity.
    Baldwin J; Farajallah AM; Malmquist NA; Rathod PK; Phillips MA
    J Biol Chem; 2002 Nov; 277(44):41827-34. PubMed ID: 12189151
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Investigating dihydroorotate dehydrogenase inhibitor mediated mitochondrial dysfunction in hepatic in vitro models.
    Jones SW; Penman SL; French NS; Park BK; Chadwick AE
    Toxicol In Vitro; 2021 Apr; 72():105096. PubMed ID: 33460737
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.
    Lucas-Hourani M; Dauzonne D; Munier-Lehmann H; Khiar S; Nisole S; Dairou J; Helynck O; Afonso PV; Tangy F; Vidalain PO
    Antimicrob Agents Chemother; 2017 Oct; 61(10):. PubMed ID: 28807907
    [No Abstract]   [Full Text] [Related]  

  • 31. 3D-QSAR studies on a series of dihydroorotate dehydrogenase inhibitors: analogues of the active metabolite of leflunomide.
    Li SL; He MY; Du HG
    Int J Mol Sci; 2011; 12(5):2982-93. PubMed ID: 21686163
    [TBL] [Abstract][Full Text] [Related]  

  • 32. SOX2-dependent expression of dihydroorotate dehydrogenase regulates oral squamous cell carcinoma cell proliferation.
    Qiu X; Jiang S; Xiao Y; He Y; Ren T; Jiang L; Liu R; Chen Q
    Int J Oral Sci; 2021 Jan; 13(1):3. PubMed ID: 33510132
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Drosophila melanogaster dihydroorotate dehydrogenase: the N-terminus is important for biological function in vivo but not for catalytic properties in vitro.
    Löffler M; Knecht W; Rawls J; Ullrich A; Dietz C
    Insect Biochem Mol Biol; 2002 Sep; 32(9):1159-69. PubMed ID: 12213251
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III.
    Khutornenko AA; Dalina AA; Chernyak BV; Chumakov PM; Evstafieva AG
    Acta Naturae; 2014 Jan; 6(1):69-75. PubMed ID: 24772329
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Efficacy and safety of dihydroorotate dehydrogenase (DHODH) inhibitors "leflunomide" and "teriflunomide" in Covid-19: A narrative review.
    Kaur H; Sarma P; Bhattacharyya A; Sharma S; Chhimpa N; Prajapat M; Prakash A; Kumar S; Singh A; Singh R; Avti P; Thota P; Medhi B
    Eur J Pharmacol; 2021 Sep; 906():174233. PubMed ID: 34111397
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis.
    Marschall M; Niemann I; Kosulin K; Bootz A; Wagner S; Dobner T; Herz T; Kramer B; Leban J; Vitt D; Stamminger T; Hutterer C; Strobl S
    Antiviral Res; 2013 Dec; 100(3):640-8. PubMed ID: 24149002
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
    Dong S; Zhang M; Cheng Z; Zhang X; Liang W; Li S; Li L; Xu Q; Song S; Liu Z; Yang G; Zhao X; Tao Z; Liang S; Wang K; Zhang G; Hu S
    Redox Biol; 2024 Jul; 73():103207. PubMed ID: 38805974
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
    Lucas-Hourani M; Munier-Lehmann H; El Mazouni F; Malmquist NA; Harpon J; Coutant EP; Guillou S; Helynck O; Noel A; Scherf A; Phillips MA; Tangy F; Vidalain PO; Janin YL
    J Med Chem; 2015 Jul; 58(14):5579-98. PubMed ID: 26079043
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Advanced virtual screening enables the discovery of a host-targeting and broad-spectrum antiviral agent.
    Chilingaryan G; Izmailyan R; Grigoryan R; Shavina A; Arabyan E; Khachatryan H; Abelyan N; Matevosyan M; Harutyunyan V; Manukyan G; Hietel B; Shtro A; Danilenko D; Zakaryan H
    Antiviral Res; 2023 Sep; 217():105681. PubMed ID: 37499699
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.
    Liu S; Neidhardt EA; Grossman TH; Ocain T; Clardy J
    Structure; 2000 Jan; 8(1):25-33. PubMed ID: 10673429
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.