BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 36142527)

  • 21. Inflammatory mediators modulate thrombin and cathepsin-G signaling in human bronchial fibroblasts by inducing expression of proteinase-activated receptor-4.
    Ramachandran R; Sadofsky LR; Xiao Y; Botham A; Cowen M; Morice AH; Compton SJ
    Am J Physiol Lung Cell Mol Physiol; 2007 Mar; 292(3):L788-98. PubMed ID: 17142351
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
    Darmoul D; Gratio V; Devaud H; Laburthe M
    J Biol Chem; 2004 May; 279(20):20927-34. PubMed ID: 15010475
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist.
    Cho NC; Seo SH; Kim D; Shin JS; Ju J; Seong J; Seo SH; Lee I; Lee KT; Kim YK; No KT; Pae AN
    J Comput Aided Mol Des; 2016 Aug; 30(8):625-37. PubMed ID: 27600555
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Basal nitric oxide modulates vascular effects of a peptide activating protease-activated receptor 2.
    Cicala C; Morello S; Vellecco V; Severino B; Sorrentino L; Cirino G
    Cardiovasc Res; 2003 Nov; 60(2):431-7. PubMed ID: 14613873
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Divergent β-arrestin-dependent signaling events are dependent upon sequences within G-protein-coupled receptor C termini.
    Pal K; Mathur M; Kumar P; DeFea K
    J Biol Chem; 2013 Feb; 288(5):3265-74. PubMed ID: 23235155
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
    Jimenez-Vargas NN; Pattison LA; Zhao P; Lieu T; Latorre R; Jensen DD; Castro J; Aurelio L; Le GT; Flynn B; Herenbrink CK; Yeatman HR; Edgington-Mitchell L; Porter CJH; Halls ML; Canals M; Veldhuis NA; Poole DP; McLean P; Hicks GA; Scheff N; Chen E; Bhattacharya A; Schmidt BL; Brierley SM; Vanner SJ; Bunnett NW
    Proc Natl Acad Sci U S A; 2018 Jul; 115(31):E7438-E7447. PubMed ID: 30012612
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling.
    Thibeault PE; Ramachandran R
    ACS Pharmacol Transl Sci; 2020 Oct; 3(5):868-882. PubMed ID: 33073187
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants.
    Cattaruzza F; Amadesi S; Carlsson JF; Murphy JE; Lyo V; Kirkwood K; Cottrell GS; Bogyo M; Knecht W; Bunnett NW
    Br J Pharmacol; 2014 Aug; 171(16):3814-26. PubMed ID: 24749982
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
    Zhao P; Lieu T; Barlow N; Metcalf M; Veldhuis NA; Jensen DD; Kocan M; Sostegni S; Haerteis S; Baraznenok V; Henderson I; Lindström E; Guerrero-Alba R; Valdez-Morales EE; Liedtke W; McIntyre P; Vanner SJ; Korbmacher C; Bunnett NW
    J Biol Chem; 2014 Sep; 289(39):27215-27234. PubMed ID: 25118282
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Differential effects of beta-arrestins on the internalization, desensitization and ERK1/2 activation downstream of protease activated receptor-2.
    Kumar P; Lau CS; Mathur M; Wang P; DeFea KA
    Am J Physiol Cell Physiol; 2007 Jul; 293(1):C346-57. PubMed ID: 17442737
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Role for β-arrestin in mediating paradoxical β2AR and PAR2 signaling in asthma.
    Walker JK; DeFea KA
    Curr Opin Pharmacol; 2014 Jun; 16():142-7. PubMed ID: 24907413
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The C-terminus of murine S100A9 protein inhibits hyperalgesia induced by the agonist peptide of protease-activated receptor 2 (PAR2).
    Dale CS; Cenac N; Britto LR; Juliano MA; Juliano L; Vergnolle N; Giorgi R
    Br J Pharmacol; 2006 Oct; 149(4):374-84. PubMed ID: 16967049
    [TBL] [Abstract][Full Text] [Related]  

  • 33. C781, a β-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice.
    Kume M; Ahmad A; Shiers S; Burton MD; DeFea KA; Vagner J; Dussor G; Boitano S; Price TJ
    J Pain; 2023 Apr; 24(4):605-616. PubMed ID: 36417966
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The protease activated receptor 2 (PAR2) polymorphic variant F240S constitutively activates PAR2 receptors and potentiates responses to small-molecule PAR2 agonists.
    Ma JN; Burstein ES
    J Pharmacol Exp Ther; 2013 Dec; 347(3):697-704. PubMed ID: 24078870
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The PAR2 signal peptide prevents premature receptor cleavage and activation.
    Liu B; Lee G; Wu J; Deming J; Kuei C; Harrington A; Wang L; Towne J; Lovenberg T; Liu C; Sun S
    PLoS One; 2020; 15(2):e0222685. PubMed ID: 32078628
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2.
    Tu NH; Jensen DD; Anderson BM; Chen E; Jimenez-Vargas NN; Scheff NN; Inoue K; Tran HD; Dolan JC; Meek TA; Hollenberg MD; Liu CZ; Vanner SJ; Janal MN; Bunnett NW; Edgington-Mitchell LE; Schmidt BL
    J Neurosci; 2021 Jan; 41(1):193-210. PubMed ID: 33172978
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The p38 mitogen-activated protein kinase pathway plays a critical role in PAR2-induced endothelial IL-8 production and leukocyte adhesion.
    Pan SL; Tao KY; Guh JH; Sun HL; Huang DY; Chang YL; Teng CM
    Shock; 2008 Nov; 30(5):496-502. PubMed ID: 18277946
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport.
    Vergnolle N; Macnaughton WK; Al-Ani B; Saifeddine M; Wallace JL; Hollenberg MD
    Proc Natl Acad Sci U S A; 1998 Jun; 95(13):7766-71. PubMed ID: 9636225
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Proteinase-activated receptor-2: key role of amino-terminal dipeptide residues of the tethered ligand for receptor activation.
    Al-Ani B; Hansen KK; Hollenberg MD
    Mol Pharmacol; 2004 Jan; 65(1):149-56. PubMed ID: 14722246
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer.
    Ayoub MA; Pin JP
    Front Endocrinol (Lausanne); 2013; 4():196. PubMed ID: 24391627
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.