These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 36145380)

  • 1. Deconstructing Markush: Improving the R&D Efficiency Using Library Selection in Early Drug Discovery.
    Manen-Freixa L; Borrell JI; Teixidó J; Estrada-Tejedor R
    Pharmaceuticals (Basel); 2022 Sep; 15(9):. PubMed ID: 36145380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploring the unexplored chemical space: Rational identification of new Tafenoquine analogs with antimalarial properties.
    Manen-Freixa L; Moliner-Cubel S; Gamo FJ; Crespo B; Borrell JI; Teixidó J; Estrada-Tejedor R
    Bioorg Chem; 2024 Jul; 148():107472. PubMed ID: 38788364
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intuitive patent Markush structure visualization tool for medicinal chemists.
    Deng W; Berthel SJ; So WV
    J Chem Inf Model; 2011 Mar; 51(3):511-20. PubMed ID: 21381694
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Use of Markush structure analysis techniques for descriptor generation and clustering of large combinatorial libraries.
    Barnard JM; Downs GM; von Scholley-Pfab A; Brown RD
    J Mol Graph Model; 2000; 18(4-5):452-63. PubMed ID: 11143562
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Novel Concept for the Search and Retrieval of the Derwent Markush Resource Database.
    Barth A; Stengel T; Litterst E; Kraut H; Matuszczyk H; Ailer F; Hajkowski S
    J Chem Inf Model; 2016 May; 56(5):821-9. PubMed ID: 27123583
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Safety screening in early drug discovery: An optimized assay panel.
    Bendels S; Bissantz C; Fasching B; Gerebtzoff G; Guba W; Kansy M; Migeon J; Mohr S; Peters JU; Tillier F; Wyler R; Lerner C; Kramer C; Richter H; Roberts S
    J Pharmacol Toxicol Methods; 2019; 99():106609. PubMed ID: 31284073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A comparison of different approaches to Markush structure handling.
    Barnard JM
    J Chem Inf Comput Sci; 1991 Feb; 31(1):64-8. PubMed ID: 2026663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space.
    Koutsoukas A; Paricharak S; Galloway WR; Spring DR; Ijzerman AP; Glen RC; Marcus D; Bender A
    J Chem Inf Model; 2014 Jan; 54(1):230-42. PubMed ID: 24289493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Locating sweet spots for screening hits and evaluating pan-assay interference filters from the performance analysis of two lead-like libraries.
    Mok NY; Maxe S; Brenk R
    J Chem Inf Model; 2013 Mar; 53(3):534-44. PubMed ID: 23451880
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A system for encoding and searching Markush structures.
    Cosgrove DA; Green KM; Leach AG; Poirrette A; Winter J
    J Chem Inf Model; 2012 Aug; 52(8):1936-47. PubMed ID: 22804819
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intelligent pharmaceutical patent search on a near-term gate-based quantum computer.
    Wang PH; Chen JH; Tseng YJ
    Sci Rep; 2022 Jan; 12(1):175. PubMed ID: 34997034
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Balancing novelty with confined chemical space in modern drug discovery.
    Medina-Franco JL; Martinez-Mayorga K; Meurice N
    Expert Opin Drug Discov; 2014 Feb; 9(2):151-65. PubMed ID: 24350718
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Machine intelligence-driven framework for optimized hit selection in virtual screening.
    Kumar N; Acharya V
    J Cheminform; 2022 Jul; 14(1):48. PubMed ID: 35869511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design of a general-purpose European compound screening library for EU-OPENSCREEN.
    Horvath D; Lisurek M; Rupp B; Kühne R; Specker E; von Kries J; Rognan D; Andersson CD; Almqvist F; Elofsson M; Enqvist PA; Gustavsson AL; Remez N; Mestres J; Marcou G; Varnek A; Hibert M; Quintana J; Frank R
    ChemMedChem; 2014 Oct; 9(10):2309-26. PubMed ID: 25044981
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biodiversity of small molecules--a new perspective in screening set selection.
    Petrone PM; Wassermann AM; Lounkine E; Kutchukian P; Simms B; Jenkins J; Selzer P; Glick M
    Drug Discov Today; 2013 Jul; 18(13-14):674-80. PubMed ID: 23454345
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Charting, navigating, and populating natural product chemical space for drug discovery.
    Lachance H; Wetzel S; Kumar K; Waldmann H
    J Med Chem; 2012 Jul; 55(13):5989-6001. PubMed ID: 22537178
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The PHARMSEARCH database.
    O'Hara MP; Pagis C
    J Chem Inf Comput Sci; 1991 Feb; 31(1):59-63. PubMed ID: 2026662
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and analysis of a combinatorial library of HEPT analogues: comparison of selection methodologies and inspection of the actually covered chemical space.
    Pascual R; Mateu M; Gasteiger J; Borrell JI; Teixidó J
    J Chem Inf Comput Sci; 2003; 43(1):199-207. PubMed ID: 12546554
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemical Space of DNA-Encoded Libraries.
    Franzini RM; Randolph C
    J Med Chem; 2016 Jul; 59(14):6629-44. PubMed ID: 26914744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Screening Compound Collection: A Key Asset for Drug Discovery.
    Boss C; Hazemann J; Kimmerlin T; von Korff M; Lüthi U; Peter O; Sander T; Siegrist R
    Chimia (Aarau); 2017 Oct; 71(10):667-677. PubMed ID: 29070412
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.