147 related articles for article (PubMed ID: 36152343)
21. The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase.
Li HY; Jin Y; Morisseau C; Hammock BD; Long YQ
Bioorg Med Chem; 2006 Oct; 14(19):6586-92. PubMed ID: 16784862
[TBL] [Abstract][Full Text] [Related]
22. A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors.
Shen HC; Ding FX; Deng Q; Xu S; Tong X; Zhang X; Chen Y; Zhou G; Pai LY; Alonso-Galicia M; Roy S; Zhang B; Tata JR; Berger JP; Colletti SL
Bioorg Med Chem Lett; 2009 Oct; 19(19):5716-21. PubMed ID: 19700315
[TBL] [Abstract][Full Text] [Related]
23. Unsymmetrical non-adamantyl N,N'-diaryl urea and amide inhibitors of soluble expoxide hydrolase.
Anandan SK; Webb HK; Do ZN; Gless RD
Bioorg Med Chem Lett; 2009 Aug; 19(15):4259-63. PubMed ID: 19520575
[TBL] [Abstract][Full Text] [Related]
24. Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability.
Pecic S; Zeki AA; Xu X; Jin GY; Zhang S; Kodani S; Halim M; Morisseau C; Hammock BD; Deng SX
Prostaglandins Other Lipid Mediat; 2018 May; 136():90-95. PubMed ID: 29567338
[TBL] [Abstract][Full Text] [Related]
25. Insight into the binding modes and inhibition mechanisms of adamantyl-based 1,3-disubstituted urea inhibitors in the active site of the human soluble epoxide hydrolase.
Chen H; Zhang Y; Ye C; Feng TT; Han JG
J Biomol Struct Dyn; 2014; 32(8):1231-47. PubMed ID: 23815795
[TBL] [Abstract][Full Text] [Related]
26. Design, synthesis and biological evaluation of 4-benzamidobenzoic Acid hydrazide derivatives as novel soluble epoxide hydrolase inhibitors.
Rezaee Zavareh E; Hedayati M; Hoghooghi Rad L; Shahhosseini S; Faizi M; Tabatabai SA
Iran J Pharm Res; 2014; 13(Suppl):51-9. PubMed ID: 24711829
[TBL] [Abstract][Full Text] [Related]
27. Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties.
Huang SX; Li HY; Liu JY; Morisseau C; Hammock BD; Long YQ
J Med Chem; 2010 Dec; 53(23):8376-86. PubMed ID: 21070033
[TBL] [Abstract][Full Text] [Related]
28. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation.
Argiriadi MA; Morisseau C; Goodrow MH; Dowdy DL; Hammock BD; Christianson DW
J Biol Chem; 2000 May; 275(20):15265-70. PubMed ID: 10747889
[TBL] [Abstract][Full Text] [Related]
29. Evaluation of structure-derived pharmacophore of soluble epoxide hydrolase inhibitors by virtual screening.
Moser D; Achenbach J; Klingler FM; Estel la B; Hahn S; Proschak E
Bioorg Med Chem Lett; 2012 Nov; 22(21):6762-5. PubMed ID: 23017883
[TBL] [Abstract][Full Text] [Related]
30. Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics.
Zhao WY; Yan JJ; Zhang M; Wang C; Feng L; Lv X; Huo XK; Sun CP; Chen LX; Ma XC
Chem Biol Interact; 2021 Aug; 345():109571. PubMed ID: 34217688
[TBL] [Abstract][Full Text] [Related]
31. Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors.
Codony S; Valverde E; Leiva R; Brea J; Isabel Loza M; Morisseau C; Hammock BD; Vázquez S
Bioorg Med Chem; 2019 Oct; 27(20):115078. PubMed ID: 31488357
[TBL] [Abstract][Full Text] [Related]
32. Non-urea functionality as the primary pharmacophore in soluble epoxide hydrolase inhibitors.
Anandan SK; Do ZN; Webb HK; Patel DV; Gless RD
Bioorg Med Chem Lett; 2009 Feb; 19(4):1066-70. PubMed ID: 19168352
[TBL] [Abstract][Full Text] [Related]
33. The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors.
de Oliveira GS; Adriani PP; Ribeiro JA; Morisseau C; Hammock BD; Dias MVB; Chambergo FS
Int J Biol Macromol; 2019 May; 129():653-658. PubMed ID: 30771398
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of
Kim JH; Park JS; Lee YJ; Choi S; Kim YH; Yang SY
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1049-1055. PubMed ID: 34000951
[TBL] [Abstract][Full Text] [Related]
35. Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors.
Burmistrov V; Morisseau C; Karlov D; Pitushkin D; Vernigora A; Rasskazova E; Butov GM; Hammock BD
Bioorg Med Chem Lett; 2020 Sep; 30(18):127430. PubMed ID: 32736212
[TBL] [Abstract][Full Text] [Related]
36. Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors.
Tian Y; Li S; Yang P; Su X; Liu J; Lv X; Dong K; Yang T; Duan M; Hu G; Yue H; Sun Y; Sun Y; Zhang H; Du Z; Miao Z; Tong M; Hou Y; Gao Z; Zhao Y
Bioorg Med Chem Lett; 2022 Aug; 70():128805. PubMed ID: 35598794
[TBL] [Abstract][Full Text] [Related]
37. Exploration of secondary and tertiary pharmacophores in unsymmetrical N,N'-diaryl urea inhibitors of soluble epoxide hydrolase.
Anandan SK; Gless RD
Bioorg Med Chem Lett; 2010 May; 20(9):2740-4. PubMed ID: 20363133
[TBL] [Abstract][Full Text] [Related]
38. In vitro and in silico investigation of anthocyanin derivatives as soluble epoxide hydrolase inhibitors.
Kim JH; Cho IS; Ryu J; Lee JS; Kang JS; Kang SY; Kim YH
Int J Biol Macromol; 2018 Jun; 112():961-967. PubMed ID: 29447963
[TBL] [Abstract][Full Text] [Related]
39. Discovery of Novel Soluble Epoxide Hydrolase Inhibitors as Potent Vasodilators.
Tripathi N; Paliwal S; Sharma S; Verma K; Gururani R; Tiwari A; Verma A; Chauhan M; Singh A; Kumar D; Pant A
Sci Rep; 2018 Oct; 8(1):14604. PubMed ID: 30279487
[TBL] [Abstract][Full Text] [Related]
40. Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase.
Lukin A; Kramer J; Hartmann M; Weizel L; Hernandez-Olmos V; Falahati K; Burghardt I; Kalinchenkova N; Bagnyukova D; Zhurilo N; Rautio J; Forsberg M; Ihalainen J; Auriola S; Leppänen J; Konstantinov I; Pogoryelov D; Proschak E; Dar'in D; Krasavin M
Bioorg Chem; 2018 Oct; 80():655-667. PubMed ID: 30059891
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
