These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 36161945)

  • 1. Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.
    Metaferia B; Cellmer T; Dunkelberger EB; Li Q; Henry ER; Hofrichter J; Staton D; Hsieh MM; Conrey AK; Tisdale JF; Chatterjee AK; Thein SL; Eaton WA
    Proc Natl Acad Sci U S A; 2022 Oct; 119(40):e2210779119. PubMed ID: 36161945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel approaches to the treatment of sickle cell disease: the potential of histone deacetylase inhibitors.
    Okam MM; Ebert BL
    Expert Rev Hematol; 2012 Jun; 5(3):303-11. PubMed ID: 22780210
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, Synthesis, and Biological Evaluation of Ester and Ether Derivatives of Antisickling Agent 5-HMF for the Treatment of Sickle Cell Disease.
    Xu GG; Pagare PP; Ghatge MS; Safo RP; Gazi A; Chen Q; David T; Alabbas AB; Musayev FN; Venitz J; Zhang Y; Safo MK; Abdulmalik O
    Mol Pharm; 2017 Oct; 14(10):3499-3511. PubMed ID: 28858508
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.
    Li Q; Henry ER; Hofrichter J; Smith JF; Cellmer T; Dunkelberger EB; Metaferia BB; Jones-Straehle S; Boutom S; Christoph GW; Wakefield TH; Link ME; Staton D; Vass ER; Miller JL; Hsieh MM; Tisdale JF; Eaton WA
    Proc Natl Acad Sci U S A; 2017 Jan; 114(5):E689-E696. PubMed ID: 28096387
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
    Henry ER; Metaferia B; Li Q; Harper J; Best RB; Glass KE; Cellmer T; Dunkelberger EB; Conrey A; Thein SL; Bunn HF; Eaton WA
    Blood; 2021 Sep; 138(13):1172-1181. PubMed ID: 34197597
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drug discovery by a basic research scientist.
    Eaton WA
    Front Mol Biosci; 2022; 9():1062346. PubMed ID: 36406264
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging disease-modifying therapies for sickle cell disease.
    Carden MA; Little J
    Haematologica; 2019 Sep; 104(9):1710-1719. PubMed ID: 31413089
    [TBL] [Abstract][Full Text] [Related]  

  • 8. VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions.
    Abdulmalik O; Pagare PP; Huang B; Xu GG; Ghatge MS; Xu X; Chen Q; Anabaraonye N; Musayev FN; Omar AM; Venitz J; Zhang Y; Safo MK
    Sci Rep; 2020 Nov; 10(1):20277. PubMed ID: 33219275
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An Investigation of Structure-Activity Relationships of Azolylacryloyl Derivatives Yielded Potent and Long-Acting Hemoglobin Modulators for Reversing Erythrocyte Sickling.
    Omar AM; Abdulmalik O; Ghatge MS; Muhammad YA; Paredes SD; El-Araby ME; Safo MK
    Biomolecules; 2020 Nov; 10(11):. PubMed ID: 33147875
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interactions of an Anti-Sickling Drug with Hemoglobin in Red Blood Cells from a Patient with Sickle Cell Anemia.
    Strader MB; Liang H; Meng F; Harper J; Ostrowski DA; Henry ER; Shet AS; Eaton WA; Thein SL; Alayash AI
    Bioconjug Chem; 2019 Mar; 30(3):568-571. PubMed ID: 30794381
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-Throughput Assay to Screen Small Molecules for Their Ability to Prevent Sickling of Red Blood Cells.
    Nakagawa A; Cooper MK; Kost-Alimova M; Berstler J; Yu B; Berra L; Klings ES; Huang MS; Heeney MM; Bloch DB; Zapol WM
    ACS Omega; 2022 Apr; 7(16):14009-14016. PubMed ID: 35559170
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rational Drug Design of Peptide-Based Therapies for Sickle Cell Disease.
    Olubiyi OO; Olagunju MO; Strodel B
    Molecules; 2019 Dec; 24(24):. PubMed ID: 31842406
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Advances in sickle cell disease treatment: from drug discovery until the patient monitoring.
    dos Santos JL; Lanaro C; Chin CM
    Cardiovasc Hematol Agents Med Chem; 2011 Apr; 9(2):113-27. PubMed ID: 21401492
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New developments in anti-sickling agents: can drugs directly prevent the polymerization of sickle haemoglobin in vivo?
    Oder E; Safo MK; Abdulmalik O; Kato GJ
    Br J Haematol; 2016 Oct; 175(1):24-30. PubMed ID: 27605087
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent insights on the medicinal chemistry of sickle cell disease.
    Dos Santos JL; Chin CM
    Curr Med Chem; 2011; 18(15):2339-58. PubMed ID: 21517749
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sickle cell disease: progress towards combination drug therapy.
    Pace BS; Starlard-Davenport A; Kutlar A
    Br J Haematol; 2021 Jul; 194(2):240-251. PubMed ID: 33471938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Emerging therapies in sickle cell disease.
    Nardo-Marino A; Brousse V; Rees D
    Br J Haematol; 2020 Jul; 190(2):149-172. PubMed ID: 32142156
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sickle cell anemia and antisickling agents then and now.
    Mehanna AS
    Curr Med Chem; 2001 Feb; 8(2):79-88. PubMed ID: 11172667
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro effects of NIPRISAN (Nix-0699): a naturally occurring, potent antisickling agent.
    Iyamu EW; Turner EA; Asakura T
    Br J Haematol; 2002 Jul; 118(1):337-43. PubMed ID: 12100171
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.
    Oksenberg D; Dufu K; Patel MP; Chuang C; Li Z; Xu Q; Silva-Garcia A; Zhou C; Hutchaleelaha A; Patskovska L; Patskovsky Y; Almo SC; Sinha U; Metcalf BW; Archer DR
    Br J Haematol; 2016 Oct; 175(1):141-53. PubMed ID: 27378309
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.