BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 36162331)

  • 1. Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations.
    Ha DP; Huang B; Wang H; Rangel DF; Van Krieken R; Liu Z; Samanta S; Neamati N; Lee AS
    Neoplasia; 2022 Nov; 33():100837. PubMed ID: 36162331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
    Rangel DF; Dubeau L; Park R; Chan P; Ha DP; Pulido MA; Mullen DJ; Vorobyova I; Zhou B; Borok Z; Offringa IA; Lee AS
    Oncogene; 2021 May; 40(20):3624-3632. PubMed ID: 33931739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.
    Spaan CN; de Boer RJ; Smit WL; van der Meer JH; van Roest M; Vermeulen JL; Koelink PJ; Becker MA; Go S; Silva J; Faller WJ; van den Brink GR; Muncan V; Heijmans J
    Life Sci Alliance; 2023 Nov; 6(11):. PubMed ID: 37643866
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer.
    Samanta S; Yang S; Debnath B; Xue D; Kuang Y; Ramkumar K; Lee AS; Ljungman M; Neamati N
    Cancer Res; 2021 Apr; 81(7):1883-1895. PubMed ID: 33531374
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
    Ha DP; Tsai YL; Lee AS
    Neoplasia; 2021 Dec; 23(12):1213-1226. PubMed ID: 34768108
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant
    Shen J; Ha DP; Zhu G; Rangel DF; Kobielak A; Gill PS; Groshen S; Dubeau L; Lee AS
    Proc Natl Acad Sci U S A; 2017 May; 114(20):E4020-E4029. PubMed ID: 28461470
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress.
    Wang CY; Guo ST; Wang JY; Liu F; Zhang YY; Yari H; Yan XG; Jin L; Zhang XD; Jiang CC
    Mol Cancer Ther; 2016 Mar; 15(3):448-59. PubMed ID: 26832792
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells.
    Terado T; Kim CJ; Ushio A; Minami K; Tambe Y; Kageyama S; Kawauchi A; Tsunoda T; Shirasawa S; Tanaka H; Inoue H
    Int J Oncol; 2022 Sep; 61(3):. PubMed ID: 35894141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.
    Luo Y; Yang Y; Liu M; Wang D; Wang F; Bi Y; Ji J; Li S; Liu Y; Chen R; Huang H; Wang X; Swidnicka-Siergiejko AK; Janowitz T; Beyaz S; Wang G; Xu S; Bialkowska AB; Luo CK; Pin CL; Liang G; Lu X; Wu M; Shroyer KR; Wolff RA; Plunkett W; Ji B; Li Z; Li E; Li X; Yang VW; Logsdon CD; Abbruzzese JL; Lu W
    Gastroenterology; 2019 Nov; 157(5):1413-1428.e11. PubMed ID: 31352001
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy.
    Guo W; Wang M; Yang Z; Liu D; Ma B; Zhao Y; Chen Y; Hu Y
    Eur J Med Chem; 2023 Dec; 261():115792. PubMed ID: 37690265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IKKβ targeting reduces KRAS-induced lung cancer angiogenesis in vitro and in vivo: A potential anti-angiogenic therapeutic target.
    Carneiro-Lobo TC; Scalabrini LC; Magalhães LDS; Cardeal LB; Rodrigues FS; Dos Santos EO; Baldwin AS; Levantini E; Giordano RJ; Bassères DS
    Lung Cancer; 2019 Apr; 130():169-178. PubMed ID: 30885340
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Zeb1 in Stromal Myofibroblasts Promotes
    Sangrador I; Molero X; Campbell F; Franch-Expósito S; Rovira-Rigau M; Samper E; Domínguez-Fraile M; Fillat C; Castells A; Vaquero EC
    Cancer Res; 2018 May; 78(10):2624-2637. PubMed ID: 29490942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator.
    Liu Z; Liu G; Ha DP; Wang J; Xiong M; Lee AS
    Proc Natl Acad Sci U S A; 2023 Aug; 120(31):e2303448120. PubMed ID: 37487081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Salvianolic acid F suppresses KRAS-dependent lung cancer cell growth through the PI3K/AKT signaling pathway.
    Hou X; Zhou C; Liang Z; Qiu H; Zhou Z; Zheng H; Li Z; Wang Y; Qi X; Lu L; Cao Y; Zheng J
    Phytomedicine; 2023 Dec; 121():155093. PubMed ID: 37783131
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung Tumorigenesis.
    Green S; Trejo CL; McMahon M
    Cancer Res; 2015 Dec; 75(24):5378-91. PubMed ID: 26567140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer.
    Miller P; Akama-Garren EH; Owen RP; Demetriou C; Carroll TM; Slee E; Al Moussawi K; Ellis M; Goldin R; O'Neill E; Lu X
    Cell Death Differ; 2023 Jul; 30(7):1619-1635. PubMed ID: 37270580
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective targeting of KRAS-driven lung tumorigenesis via unresolved ER stress.
    Shimomura I; Watanabe N; Yamamoto T; Kumazaki M; Tada Y; Tatsumi K; Ochiya T; Yamamoto Y
    JCI Insight; 2021 Apr; 6(7):. PubMed ID: 33830081
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression.
    Okayama H; Saito M; Oue N; Weiss JM; Stauffer J; Takenoshita S; Wiltrout RH; Hussain SP; Harris CC
    Int J Cancer; 2013 Jan; 132(1):9-18. PubMed ID: 22618808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers.
    Cheng R; Li F; Zhang M; Xia X; Wu J; Gao X; Zhou H; Zhang Z; Huang N; Yang X; Zhang Y; Shen S; Kang T; Liu Z; Xiao F; Yao H; Xu J; Yan C; Zhang N
    Cell Res; 2023 Jan; 33(1):30-45. PubMed ID: 36241718
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.
    Dumartin L; Alrawashdeh W; Trabulo SM; Radon TP; Steiger K; Feakins RM; di Magliano MP; Heeschen C; Esposito I; Lemoine NR; Crnogorac-Jurcevic T
    Oncogene; 2017 Jun; 36(22):3094-3103. PubMed ID: 27941872
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.