143 related articles for article (PubMed ID: 36167425)
1.
Ren X; Diao X; Zhuang J; Wu D
Mol Pharmacol; 2022 Sep; ():. PubMed ID: 36167425
[TBL] [Abstract][Full Text] [Related]
2. Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics.
Motta S; Minici C; Corrada D; Bonati L; Pandini A
PLoS Comput Biol; 2018 Feb; 14(2):e1006021. PubMed ID: 29489822
[TBL] [Abstract][Full Text] [Related]
3. Decoding Allosteric Control in Hypoxia-Inducible Factors.
Zhuang J; Shang Q; Rastinejad F; Wu D
J Mol Biol; 2024 Feb; 436(3):168352. PubMed ID: 37935255
[TBL] [Abstract][Full Text] [Related]
4. Bidirectional modulation of HIF-2 activity through chemical ligands.
Wu D; Su X; Lu J; Li S; Hood BL; Vasile S; Potluri N; Diao X; Kim Y; Khorasanizadeh S; Rastinejad F
Nat Chem Biol; 2019 Apr; 15(4):367-376. PubMed ID: 30804532
[TBL] [Abstract][Full Text] [Related]
5. Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.
Guo Y; Scheuermann TH; Partch CL; Tomchick DR; Gardner KH
J Biol Chem; 2015 Mar; 290(12):7707-21. PubMed ID: 25627682
[TBL] [Abstract][Full Text] [Related]
6. Belzutifan, HIF-2α Inhibitor, and Clear Cell Renal Cell Carcinoma With Somatic Von-Hippel-Lindau Loss-of-Function Mutation.
Chan KH; Li N; Lador R; Amsbaugh M; Gonzalez A; Cen P
J Investig Med High Impact Case Rep; 2024; 12():23247096241231641. PubMed ID: 38344974
[TBL] [Abstract][Full Text] [Related]
7. Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.
Erbel PJ; Card PB; Karakuzu O; Bruick RK; Gardner KH
Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15504-9. PubMed ID: 14668441
[TBL] [Abstract][Full Text] [Related]
8. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
9. Belzutifan: A Narrative Drug Review.
Visweswaran V; Pavithran K
Curr Drug Res Rev; 2022; 14(2):88-95. PubMed ID: 35366789
[TBL] [Abstract][Full Text] [Related]
10. Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.
Card PB; Erbel PJ; Gardner KH
J Mol Biol; 2005 Oct; 353(3):664-77. PubMed ID: 16181639
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of hypoxia-inducible factor-2α in renal cell carcinoma with belzutifan: a phase 1 trial and biomarker analysis.
Choueiri TK; Bauer TM; Papadopoulos KP; Plimack ER; Merchan JR; McDermott DF; Michaelson MD; Appleman LJ; Thamake S; Perini RF; Zojwalla NJ; Jonasch E
Nat Med; 2021 May; 27(5):802-805. PubMed ID: 33888901
[TBL] [Abstract][Full Text] [Related]
12. Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators.
Chapman-Smith A; Lutwyche JK; Whitelaw ML
J Biol Chem; 2004 Feb; 279(7):5353-62. PubMed ID: 14638687
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of the Hypoxia-Inducible Factor-2
Hamal KB; Pavlich CI; Carlson GJ; Wong YC; Zhao F; Zhang Q; Klausmeyer KK; Pinney KG
Tetrahedron Lett; 2023 Sep; 128():. PubMed ID: 38343394
[TBL] [Abstract][Full Text] [Related]
14. Belzutifan (MK-6482): Biology and Clinical Development in Solid Tumors.
Choi WW; Boland JL; Kalola A; Lin J
Curr Oncol Rep; 2023 Feb; 25(2):123-129. PubMed ID: 36630072
[TBL] [Abstract][Full Text] [Related]
15. Novel Approaches with HIF-2α Targeted Therapies in Metastatic Renal Cell Carcinoma.
Nguyen CB; Oh E; Bahar P; Vaishampayan UN; Else T; Alva AS
Cancers (Basel); 2024 Jan; 16(3):. PubMed ID: 38339352
[TBL] [Abstract][Full Text] [Related]
16. ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma.
Persson CU; von Stedingk K; Fredlund E; Bexell D; Påhlman S; Wigerup C; Mohlin S
Exp Cell Res; 2020 Mar; 388(2):111845. PubMed ID: 31945318
[TBL] [Abstract][Full Text] [Related]
17. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.
Gradin K; McGuire J; Wenger RH; Kvietikova I; fhitelaw ML; Toftgård R; Tora L; Gassmann M; Poellinger L
Mol Cell Biol; 1996 Oct; 16(10):5221-31. PubMed ID: 8816435
[TBL] [Abstract][Full Text] [Related]
18. Belzutifan: First Approval.
Deeks ED
Drugs; 2021 Nov; 81(16):1921-1927. PubMed ID: 34613603
[TBL] [Abstract][Full Text] [Related]
19. Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status.
Messai Y; Gad S; Noman MZ; Le Teuff G; Couve S; Janji B; Kammerer SF; Rioux-Leclerc N; Hasmim M; Ferlicot S; Baud V; Mejean A; Mole DR; Richard S; Eggermont AM; Albiges L; Mami-Chouaib F; Escudier B; Chouaib S
Eur Urol; 2016 Oct; 70(4):623-632. PubMed ID: 26707870
[TBL] [Abstract][Full Text] [Related]
20. Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor.
Kallio PJ; Pongratz I; Gradin K; McGuire J; Poellinger L
Proc Natl Acad Sci U S A; 1997 May; 94(11):5667-72. PubMed ID: 9159130
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
