139 related articles for article (PubMed ID: 3617098)
1. Microsomal metabolism of pyrrolizidine alkaloids: N-oxidation of seneciphylline and senecionine.
Ramsdell HS; Buhler DR
Toxicol Lett; 1987 Aug; 37(3):241-9. PubMed ID: 3617098
[TBL] [Abstract][Full Text] [Related]
2. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
Wang YP; Yan J; Fu PP; Chou MW
Toxicol Lett; 2005 Mar; 155(3):411-20. PubMed ID: 15649625
[TBL] [Abstract][Full Text] [Related]
3. The role of flavin-containing monooxygenase in the N-oxidation of the pyrrolizidine alkaloid senecionine.
Williams DE; Reed RL; Kedzierski B; Ziegler DM; Buhler DR
Drug Metab Dispos; 1989; 17(4):380-6. PubMed ID: 2571476
[TBL] [Abstract][Full Text] [Related]
4. Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.
Duringer JM; Buhler DR; Craig AM
Am J Vet Res; 2004 Nov; 65(11):1563-72. PubMed ID: 15566096
[TBL] [Abstract][Full Text] [Related]
5. Flavin-containing monooxygenase: a major detoxifying enzyme for the pyrrolizidine alkaloid senecionine in guinea pig tissues.
Miranda CL; Chung W; Reed RE; Zhao X; Henderson MC; Wang JL; Williams DE; Buhler DR
Biochem Biophys Res Commun; 1991 Jul; 178(2):546-52. PubMed ID: 1907134
[TBL] [Abstract][Full Text] [Related]
6. Role of cytochrome P450IIIA4 in the metabolism of the pyrrolizidine alkaloid senecionine in human liver.
Miranda CL; Reed RL; Guengerich FP; Buhler DR
Carcinogenesis; 1991 Mar; 12(3):515-9. PubMed ID: 2009596
[TBL] [Abstract][Full Text] [Related]
7. The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.
Chung WG; Buhler DR
Toxicol Appl Pharmacol; 1994 Aug; 127(2):314-9. PubMed ID: 8048076
[TBL] [Abstract][Full Text] [Related]
8. Microsomal metabolism of pyrrolizidine alkaloids from Senecio jacobaea. Isolation and quantification of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine and N-oxides by high performance liquid chromatography.
Ramsdell HS; Kedzierski B; Buhler DR
Drug Metab Dispos; 1987; 15(1):32-6. PubMed ID: 2881756
[TBL] [Abstract][Full Text] [Related]
9. Species differences in the hepatic microsomal enzyme metabolism of the pyrrolizidine alkaloids.
Huan JY; Miranda CL; Buhler DR; Cheeke PR
Toxicol Lett; 1998 Oct; 99(2):127-37. PubMed ID: 9817084
[TBL] [Abstract][Full Text] [Related]
10. Species differences in the hepatic microsomal metabolism of the pyrrolizidine alkaloid senecionine.
Winter CK; Segall HJ; Jones AD
Comp Biochem Physiol C Comp Pharmacol Toxicol; 1988; 90(2):429-33. PubMed ID: 2903002
[TBL] [Abstract][Full Text] [Related]
11. Metabolic activation of pyrrolizidine alkaloids by human, rat and avocado microsomes.
Couet CE; Hopley J; Hanley AB
Toxicon; 1996 Sep; 34(9):1058-61. PubMed ID: 8896199
[TBL] [Abstract][Full Text] [Related]
12. Method for determination of pyrrolizidine alkaloids and their metabolites by high-performance liquid chromatography.
Kedzierski B; Buhler DR
Anal Biochem; 1986 Jan; 152(1):59-65. PubMed ID: 3954045
[TBL] [Abstract][Full Text] [Related]
13. Biological reactive intermediates of pyrrolizidine alkaloids.
Buhler DR; Kedzierski B
Adv Exp Med Biol; 1986; 197():611-20. PubMed ID: 3766284
[No Abstract] [Full Text] [Related]
14. Differential metabolism of the pyrrolizidine alkaloid, senecionine, in Fischer 344 and Sprague-Dawley rats.
Chung WG; Buhler DR
Arch Pharm Res; 2004 May; 27(5):547-53. PubMed ID: 15202562
[TBL] [Abstract][Full Text] [Related]
15. The two facies of pyrrolizidine alkaloids: the role of the tertiary amine and its N-oxide in chemical defense of insects with acquired plant alkaloids.
Lindigkeit R; Biller A; Buch M; Schiebel HM; Boppré M; Hartmann T
Eur J Biochem; 1997 May; 245(3):626-36. PubMed ID: 9182998
[TBL] [Abstract][Full Text] [Related]
16. Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver.
Williams DE; Reed RL; Kedzierski B; Dannan GA; Guengerich FP; Buhler DR
Drug Metab Dispos; 1989; 17(4):387-92. PubMed ID: 2571477
[TBL] [Abstract][Full Text] [Related]
17. A new pyrrolizidine alkaloid metabolite, 19-hydroxysenecionine isolated from mouse hepatic microsomes in vitro.
Eastman DF; Segall HJ
Drug Metab Dispos; 1982; 10(6):696-9. PubMed ID: 6130926
[TBL] [Abstract][Full Text] [Related]
18. Microsomal formation of a pyrrolic alcohol glutathione conjugate of the pyrrolizidine alkaloid senecionine.
Reed RL; Miranda CL; Kedzierski B; Henderson MC; Buhler DR
Xenobiotica; 1992 Nov; 22(11):1321-7. PubMed ID: 1492424
[TBL] [Abstract][Full Text] [Related]
19. Rat liver cytochrome P450 metabolism of N-acetylbenzidine and N,N'-diacetylbenzidine.
Lakshmi VM; Zenser TV; Davis BB
Drug Metab Dispos; 1997 Apr; 25(4):481-8. PubMed ID: 9107548
[TBL] [Abstract][Full Text] [Related]
20. A cytochrome P4502B form is the major bioactivation enzyme for the pyrrolizidine alkaloid senecionine in guinea pig.
Chung WG; Miranda CL; Buhler DR
Xenobiotica; 1995 Sep; 25(9):929-39. PubMed ID: 8553686
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]