245 related articles for article (PubMed ID: 36172042)
1. Allosteric regulation of substrate channeling:
Ghosh RK; Hilario E; Chang CA; Mueller LJ; Dunn MF
Front Mol Biosci; 2022; 9():923042. PubMed ID: 36172042
[TBL] [Abstract][Full Text] [Related]
2. Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex.
Dunn MF
Arch Biochem Biophys; 2012 Mar; 519(2):154-66. PubMed ID: 22310642
[TBL] [Abstract][Full Text] [Related]
3. Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands.
Ngo H; Kimmich N; Harris R; Niks D; Blumenstein L; Kulik V; Barends TR; Schlichting I; Dunn MF
Biochemistry; 2007 Jul; 46(26):7740-53. PubMed ID: 17559232
[TBL] [Abstract][Full Text] [Related]
4. beta-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex.
Pan P; Dunn MF
Biochemistry; 1996 Apr; 35(15):5002-13. PubMed ID: 8664293
[TBL] [Abstract][Full Text] [Related]
5. Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex.
Brzović PS; Ngo K; Dunn MF
Biochemistry; 1992 Apr; 31(15):3831-9. PubMed ID: 1567839
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.
Ngo H; Harris R; Kimmich N; Casino P; Niks D; Blumenstein L; Barends TR; Kulik V; Weyand M; Schlichting I; Dunn MF
Biochemistry; 2007 Jul; 46(26):7713-27. PubMed ID: 17559195
[TBL] [Abstract][Full Text] [Related]
7. Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding.
Casino P; Niks D; Ngo H; Pan P; Brzovic P; Blumenstein L; Barends TR; Schlichting I; Dunn MF
Biochemistry; 2007 Jul; 46(26):7728-39. PubMed ID: 17559231
[TBL] [Abstract][Full Text] [Related]
8. The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel.
Dunn MF; Aguilar V; Brzović P; Drewe WF; Houben KF; Leja CA; Roy M
Biochemistry; 1990 Sep; 29(37):8598-607. PubMed ID: 2271543
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the functional role of a flexible loop in the alpha-subunit of tryptophan synthase from Salmonella typhimurium by rapid-scanning, stopped-flow spectroscopy and site-directed mutagenesis.
Brzović PS; Hyde CC; Miles EW; Dunn MF
Biochemistry; 1993 Oct; 32(39):10404-13. PubMed ID: 8399184
[TBL] [Abstract][Full Text] [Related]
10. Allosteric linkages between beta-site covalent transformations and alpha-site activation and deactivation in the tryptophan synthase bienzyme complex.
Leja CA; Woehl EU; Dunn MF
Biochemistry; 1995 May; 34(19):6552-61. PubMed ID: 7756286
[TBL] [Abstract][Full Text] [Related]
11. Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase.
Schlichting I; Yang XJ; Miles EW; Kim AY; Anderson KS
J Biol Chem; 1994 Oct; 269(43):26591-3. PubMed ID: 7929385
[TBL] [Abstract][Full Text] [Related]
12. Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
Niks D; Hilario E; Dierkers A; Ngo H; Borchardt D; Neubauer TJ; Fan L; Mueller LJ; Dunn MF
Biochemistry; 2013 Sep; 52(37):6396-411. PubMed ID: 23952479
[TBL] [Abstract][Full Text] [Related]
13. Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
Michalska K; Wellington S; Maltseva N; Jedrzejczak R; Selem-Mojica N; Rosas-Becerra LR; Barona-Gómez F; Hung DT; Joachimiak A
Protein Sci; 2021 Sep; 30(9):1904-1918. PubMed ID: 34107106
[TBL] [Abstract][Full Text] [Related]
14. Intermediate trapping via a conformational switch in the Na(+)-activated tryptophan synthase bienzyme complex.
Harris RM; Dunn MF
Biochemistry; 2002 Aug; 41(31):9982-90. PubMed ID: 12146962
[TBL] [Abstract][Full Text] [Related]
15. Mutation of βGln114 to Ala Alters the Stabilities of Allosteric States in Tryptophan Synthase Catalysis.
Ghosh RK; Hilario E; Liu V; Wang Y; Niks D; Holmes JB; Sakhrani VV; Mueller LJ; Dunn MF
Biochemistry; 2021 Oct; 60(42):3173-3186. PubMed ID: 34595921
[TBL] [Abstract][Full Text] [Related]
16. Analysis of allosteric communication in a multienzyme complex by ancestral sequence reconstruction.
Schupfner M; Straub K; Busch F; Merkl R; Sterner R
Proc Natl Acad Sci U S A; 2020 Jan; 117(1):346-354. PubMed ID: 31871208
[TBL] [Abstract][Full Text] [Related]
17. Protein architecture, dynamics and allostery in tryptophan synthase channeling.
Pan P; Woehl E; Dunn MF
Trends Biochem Sci; 1997 Jan; 22(1):22-7. PubMed ID: 9020588
[TBL] [Abstract][Full Text] [Related]
18. Investigation of allosteric linkages in the regulation of tryptophan synthase: the roles of salt bridges and monovalent cations probed by site-directed mutation, optical spectroscopy, and kinetics.
Weber-Ban E; Hur O; Bagwell C; Banik U; Yang LH; Miles EW; Dunn MF
Biochemistry; 2001 Mar; 40(12):3497-511. PubMed ID: 11297416
[TBL] [Abstract][Full Text] [Related]
19. Tryptophan synthase: a multienzyme complex with an intramolecular tunnel.
Miles EW
Chem Rec; 2001; 1(2):140-51. PubMed ID: 11893063
[TBL] [Abstract][Full Text] [Related]
20. Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium.
Brzović PS; Kayastha AM; Miles EW; Dunn MF
Biochemistry; 1992 Feb; 31(4):1180-90. PubMed ID: 1346502
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
