BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 36175619)

  • 1. Mutation of the proline P81 into a serine modifies the tumour suppressor function of the von Hippel-Lindau gene in the ccRCC.
    Chesnel F; Jullion E; Delalande O; Couturier A; Alusse A; Le Goff X; Lenglet M; Gardie B; Abadie C; Arlot-Bonnemains Y
    Br J Cancer; 2022 Nov; 127(11):1954-1962. PubMed ID: 36175619
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response.
    Desimone MC; Rathmell WK; Threadgill DW
    J Natl Cancer Inst; 2013 Sep; 105(18):1355-64. PubMed ID: 23990666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
    Zatyka M; da Silva NF; Clifford SC; Morris MR; Wiesener MS; Eckardt KU; Houlston RS; Richards FM; Latif F; Maher ER
    Cancer Res; 2002 Jul; 62(13):3803-11. PubMed ID: 12097293
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status.
    Messai Y; Gad S; Noman MZ; Le Teuff G; Couve S; Janji B; Kammerer SF; Rioux-Leclerc N; Hasmim M; Ferlicot S; Baud V; Mejean A; Mole DR; Richard S; Eggermont AM; Albiges L; Mami-Chouaib F; Escudier B; Chouaib S
    Eur Urol; 2016 Oct; 70(4):623-632. PubMed ID: 26707870
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.
    Gossage L; Pires DE; Olivera-Nappa Á; Asenjo J; Bycroft M; Blundell TL; Eisen T
    Hum Mol Genet; 2014 Nov; 23(22):5976-88. PubMed ID: 24969085
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Germline mutations in the VHL gene associated with 3 different renal lesions in a Chinese von Hippel-Lindau disease family.
    Yuan P; Sun Q; Liang H; Wang W; Li L; Wang Y; Deng H; Lai L; Chen X; Zhou X
    Cancer Biol Ther; 2016 Jun; 17(6):599-603. PubMed ID: 27057652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma.
    Razafinjatovo CF; Stiehl D; Deininger E; Rechsteiner M; Moch H; Schraml P
    Oncotarget; 2017 Feb; 8(6):10199-10212. PubMed ID: 28052007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel missense mutation (N78D) in a family with von Hippel-Lindau disease with central nervous system haemangioblastomas, pancreatic and renal cysts.
    Cingoz S; van der Luijt RB; Kurt E; Apaydin M; Akkol I; Ozgen MH
    Fam Cancer; 2013 Mar; 12(1):111-7. PubMed ID: 23224817
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Algorithmic assessment of missense mutation severity in the Von-Hippel Lindau protein.
    Fields FR; Suresh N; Hiller M; Freed SD; Haldar K; Lee SW
    PLoS One; 2020; 15(11):e0234100. PubMed ID: 33151962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.
    Guinot A; Lehmann H; Wild PJ; Frew IJ
    J Pathol; 2016 Jul; 239(3):365-73. PubMed ID: 27126173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VHL, the story of a tumour suppressor gene.
    Gossage L; Eisen T; Maher ER
    Nat Rev Cancer; 2015 Jan; 15(1):55-64. PubMed ID: 25533676
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Von-Hippel-Lindau (VHL) protein function by initiation and progression of renal cancer].
    Moch H
    Pathologe; 2008 Nov; 29 Suppl 2():149-52. PubMed ID: 18751708
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genotype-phenotype correlations, and retinal function and structure in von Hippel-Lindau disease.
    Wittström E; Nordling M; Andréasson S
    Ophthalmic Genet; 2014 Jun; 35(2):91-106. PubMed ID: 24555745
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Management of Gene Variants of Unknown Significance: Analysis Method and Risk Assessment of the
    Alosi D; Bisgaard ML; Hemmingsen SN; Krogh LN; Mikkelsen HB; Binderup MLM
    Curr Genomics; 2017 Feb; 18(1):93-103. PubMed ID: 28503092
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Whole-Exome Sequencing Identifies the VHL Mutation (c.262T > C, p.Try88Arg) in Non-Obstructive Azoospermia-Associated Cystic Renal Cell Carcinoma.
    Man Y; Shang X; Liu C; Zhang W; Huang Q; Ma S; Shiang R; Zhang F; Zhang L; Zhang Z
    Curr Oncol; 2022 Mar; 29(4):2376-2384. PubMed ID: 35448166
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Clinical and molecular characterization of Brazilian families with von Hippel-Lindau disease: a need for delineating genotype-phenotype correlation.
    Gomy I; Molfetta GA; de Andrade Barreto E; Ferreira CA; Zanette DL; Casali-da-Rocha JC; Silva WA
    Fam Cancer; 2010 Dec; 9(4):635-42. PubMed ID: 20567917
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Clinical and molecular features of familial and sporadic cases of von Hippel-Lindau disease from Mexico.
    Chacon-Camacho OF; Rodriguez-Dennen F; Camacho-Molina A; Rasmussen A; Alonso-Vilatela E; Zenteno JC
    Clin Exp Ophthalmol; 2010 Apr; 38(3):277-83. PubMed ID: 20447124
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease.
    Gattolliat CH; Couvé S; Meurice G; Oréar C; Droin N; Chiquet M; Ferlicot S; Verkarre V; Vasiliu V; Molinié V; Méjean A; Dessen P; Giraud S; Bressac-De-Paillerets B; Gardie B; Tean Teh B; Richard S; Gad S
    Int J Oncol; 2018 Oct; 53(4):1455-1468. PubMed ID: 30066860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Renal cell carcinoma- and pheochromocytoma-specific altered gene expression profiles in VHL mutant clones.
    Tsuchiya MI; Okuda H; Takaki Y; Baba M; Hirai S; Ohno S; Shuin T
    Oncol Rep; 2005 Jun; 13(6):1033-41. PubMed ID: 15870918
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The von Hippel-Lindau Tumor Suppressor Gene: Implications and Therapeutic Opportunities.
    Elias R; Zhang Q; Brugarolas J
    Cancer J; 2020; 26(5):390-398. PubMed ID: 32947307
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.