214 related articles for article (PubMed ID: 36192747)
21. Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity.
Haqqani AS; Thom G; Burrell M; Delaney CE; Brunette E; Baumann E; Sodja C; Jezierski A; Webster C; Stanimirovic DB
J Neurochem; 2018 Sep; 146(6):735-752. PubMed ID: 29877588
[TBL] [Abstract][Full Text] [Related]
22. Standardized Preclinical
Morrison JI; Petrovic A; Metzendorf NG; Rofo F; Yilmaz CU; Stenler S; Laudon H; Hultqvist G
Mol Pharm; 2023 Mar; 20(3):1564-1576. PubMed ID: 36808999
[TBL] [Abstract][Full Text] [Related]
23. Blood-brain barrier transport using a high affinity, brain-selective VNAR antibody targeting transferrin receptor 1.
Stocki P; Szary J; Rasmussen CLM; Demydchuk M; Northall L; Logan DB; Gauhar A; Thei L; Moos T; Walsh FS; Rutkowski JL
FASEB J; 2021 Feb; 35(2):e21172. PubMed ID: 33241587
[TBL] [Abstract][Full Text] [Related]
24. Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.
Couch JA; Yu YJ; Zhang Y; Tarrant JM; Fuji RN; Meilandt WJ; Solanoy H; Tong RK; Hoyte K; Luk W; Lu Y; Gadkar K; Prabhu S; Ordonia BA; Nguyen Q; Lin Y; Lin Z; Balazs M; Scearce-Levie K; Ernst JA; Dennis MS; Watts RJ
Sci Transl Med; 2013 May; 5(183):183ra57, 1-12. PubMed ID: 23636093
[TBL] [Abstract][Full Text] [Related]
25. Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model.
Zhao P; Anami Y; Gao P; Fan X; Li L; Tsuchikama K; Zhang N; An Z
MAbs; 2022; 14(1):2057269. PubMed ID: 35388745
[TBL] [Abstract][Full Text] [Related]
26. A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules.
Crook ZR; Girard E; Sevilla GP; Merrill M; Friend D; Rupert PB; Pakiam F; Nguyen E; Yin C; Ruff RO; Hopping G; Strand AD; Finton KAK; Coxon M; Mhyre AJ; Strong RK; Olson JM
J Mol Biol; 2020 Jun; 432(14):3989-4009. PubMed ID: 32304700
[TBL] [Abstract][Full Text] [Related]
27. Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core.
Clark AJ; Davis ME
Proc Natl Acad Sci U S A; 2015 Oct; 112(40):12486-91. PubMed ID: 26392563
[TBL] [Abstract][Full Text] [Related]
28. Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport.
Ruderisch N; Schlatter D; Kuglstatter A; Guba W; Huber S; Cusulin C; Benz J; Rufer AC; Hoernschemeyer J; Schweitzer C; Bülau T; Gärtner A; Hoffmann E; Niewoehner J; Patsch C; Baumann K; Loetscher H; Kitas E; Freskgård PO
EBioMedicine; 2017 Oct; 24():76-92. PubMed ID: 28923680
[TBL] [Abstract][Full Text] [Related]
29. Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor.
Hultqvist G; Syvänen S; Fang XT; Lannfelt L; Sehlin D
Theranostics; 2017; 7(2):308-318. PubMed ID: 28042336
[TBL] [Abstract][Full Text] [Related]
30. Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central nervous system.
Chang HY; Wu S; Chowdhury EA; Shah DK
J Pharmacokinet Pharmacodyn; 2022 Jun; 49(3):337-362. PubMed ID: 35092540
[TBL] [Abstract][Full Text] [Related]
31. Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor.
Wiley DT; Webster P; Gale A; Davis ME
Proc Natl Acad Sci U S A; 2013 May; 110(21):8662-7. PubMed ID: 23650374
[TBL] [Abstract][Full Text] [Related]
32. Blood-brain barrier drug delivery of IgG fusion proteins with a transferrin receptor monoclonal antibody.
Pardridge WM
Expert Opin Drug Deliv; 2015 Feb; 12(2):207-22. PubMed ID: 25138991
[TBL] [Abstract][Full Text] [Related]
33. The 46.1 Antibody Mediates Neurotensin Uptake into the CNS and the Effects Depend on the Route of Intravenous Administration.
Georgieva JV; Katt M; Ye Z; Umlauf BJ; Wenthur CJ; Shusta EV
Pharmaceutics; 2022 Aug; 14(8):. PubMed ID: 36015332
[TBL] [Abstract][Full Text] [Related]
34. Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules.
Kitamura K; Okamoto A; Morio H; Isogai R; Ito R; Yamaura Y; Izumi S; Komori T; Ito S; Ohtsuki S; Akita H; Furihata T
Mol Pharm; 2022 Aug; 19(8):2754-2764. PubMed ID: 35766901
[TBL] [Abstract][Full Text] [Related]
35. Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26.
Thom G; Burrell M; Haqqani AS; Yogi A; Lessard E; Brunette E; Delaney C; Baumann E; Callaghan D; Rodrigo N; Webster CI; Stanimirovic DB
Mol Pharm; 2018 Apr; 15(4):1420-1431. PubMed ID: 29485883
[TBL] [Abstract][Full Text] [Related]
36. Enhanced
Esparza TJ; Su S; Francescutti CM; Rodionova E; Kim JH; Brody DL
bioRxiv; 2023 Apr; ():. PubMed ID: 37333358
[TBL] [Abstract][Full Text] [Related]
37. A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo.
Atwal JK; Chen Y; Chiu C; Mortensen DL; Meilandt WJ; Liu Y; Heise CE; Hoyte K; Luk W; Lu Y; Peng K; Wu P; Rouge L; Zhang Y; Lazarus RA; Scearce-Levie K; Wang W; Wu Y; Tessier-Lavigne M; Watts RJ
Sci Transl Med; 2011 May; 3(84):84ra43. PubMed ID: 21613622
[TBL] [Abstract][Full Text] [Related]
38. Isolation of blood-brain barrier-crossing antibodies from a phage display library by competitive elution and their ability to penetrate the central nervous system.
Thom G; Hatcher J; Hearn A; Paterson J; Rodrigo N; Beljean A; Gurrell I; Webster C
MAbs; 2018; 10(2):304-314. PubMed ID: 29182455
[TBL] [Abstract][Full Text] [Related]
39. Transferrin Receptor-Mediated Uptake at the Blood-Brain Barrier Is Not Impaired by Alzheimer's Disease Neuropathology.
Bourassa P; Alata W; Tremblay C; Paris-Robidas S; Calon F
Mol Pharm; 2019 Feb; 16(2):583-594. PubMed ID: 30609376
[TBL] [Abstract][Full Text] [Related]
40. Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells.
Nielsen SSE; Holst MR; Langthaler K; Christensen SC; Bruun EH; Brodin B; Nielsen MS
Fluids Barriers CNS; 2023 Jan; 20(1):2. PubMed ID: 36624498
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]