These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 36193681)

  • 1. Small Molecule Tools to Study Cellular Target Engagement for the Intracellular Allosteric Binding Site of GPCRs.
    Huber ME; Toy L; Schmidt MF; Weikert D; Schiedel M
    Chemistry; 2023 Jan; 29(1):e202202565. PubMed ID: 36193681
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the Chemokine Receptor CCR2.
    Toy L; Huber ME; Schmidt MF; Weikert D; Schiedel M
    ACS Chem Biol; 2022 Aug; 17(8):2142-2152. PubMed ID: 35838163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacologically targeting intracellular allosteric sites of GPCRs for drug discovery.
    Zhang M; Lan X; Li X; Lu S
    Drug Discov Today; 2023 Dec; 28(12):103803. PubMed ID: 37852356
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fluorescent Ligands Enable Target Engagement Studies for the Intracellular Allosteric Binding Site of the Chemokine Receptor CXCR2.
    Huber ME; Wurnig S; Toy L; Weiler C; Merten N; Kostenis E; Hansen FK; Schiedel M
    J Med Chem; 2023 Jul; 66(14):9916-9933. PubMed ID: 37463496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric modulation of GPCRs: From structural insights to in silico drug discovery.
    Persechino M; Hedderich JB; Kolb P; Hilger D
    Pharmacol Ther; 2022 Sep; 237():108242. PubMed ID: 35863587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Chemical Biology Toolbox Targeting the Intracellular Binding Site of CCR9: Fluorescent Ligands, New Drug Leads and PROTACs.
    Huber ME; Toy L; Schmidt MF; Vogt H; Budzinski J; Wiefhoff MFJ; Merten N; Kostenis E; Weikert D; Schiedel M
    Angew Chem Int Ed Engl; 2022 Mar; 61(12):e202116782. PubMed ID: 34936714
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts.
    Wold EA; Chen J; Cunningham KA; Zhou J
    J Med Chem; 2019 Jan; 62(1):88-127. PubMed ID: 30106578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intracellular Receptor Modulation: Novel Approach to Target GPCRs.
    Ortiz Zacarías NV; Lenselink EB; IJzerman AP; Handel TM; Heitman LH
    Trends Pharmacol Sci; 2018 Jun; 39(6):547-559. PubMed ID: 29653834
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Is there a common allosteric binding site for G-protein coupled receptors?
    Malik F; Li Z
    J Comput Aided Mol Des; 2022 Jun; 36(6):405-413. PubMed ID: 35507106
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel Allosteric Modulators of G Protein-coupled Receptors.
    Gentry PR; Sexton PM; Christopoulos A
    J Biol Chem; 2015 Aug; 290(32):19478-88. PubMed ID: 26100627
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.
    Lu S; Zhang J
    J Med Chem; 2019 Jan; 62(1):24-45. PubMed ID: 29457894
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Leveraging allostery to improve G protein-coupled receptor (GPCR)-directed therapeutics: cannabinoid receptor 1 as discovery target.
    Janero DR; Thakur GA
    Expert Opin Drug Discov; 2016 Dec; 11(12):1223-1237. PubMed ID: 27712124
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric inhibition of g-protein coupled receptor oligomerization: strategies and challenges for drug development.
    Hurevich M; Talhami A; Shalev DE; Gilon C
    Curr Top Med Chem; 2014; 14(15):1842-63. PubMed ID: 25175995
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GPCR Allosteric Modulator Discovery.
    Wu Y; Tong J; Ding K; Zhou Q; Zhao S
    Adv Exp Med Biol; 2019; 1163():225-251. PubMed ID: 31707706
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors.
    Zhang L; Mobbs JI; May LT; Glukhova A; Thal DM
    Curr Opin Struct Biol; 2023 Apr; 79():102560. PubMed ID: 36848776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Current Trends in GPCR Allostery.
    Singh KD; Karnik SS
    J Membr Biol; 2021 Jun; 254(3):293-300. PubMed ID: 33471142
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacology of Free Fatty Acid Receptors and Their Allosteric Modulators.
    Grundmann M; Bender E; Schamberger J; Eitner F
    Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33578942
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G Protein-Coupled Receptors.
    Chan WKB; Carlson HA; Traynor JR
    Mol Pharmacol; 2023 May; 103(5):274-285. PubMed ID: 36868791
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of new GPCR ligands to illuminate new biology.
    Roth BL; Irwin JJ; Shoichet BK
    Nat Chem Biol; 2017 Nov; 13(11):1143-1151. PubMed ID: 29045379
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of fluorescent peptide G protein-coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators.
    Farmer JP; Mistry SN; Laughton CA; Holliday ND
    FASEB J; 2022 Nov; 36(11):e22576. PubMed ID: 36183332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.