BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 36193897)

  • 1. Coffee modulates insulin-hepatocyte nuclear factor-4α-Cyp7b1 pathway and reduces oxysterol-driven liver toxicity in a nonalcoholic fatty liver disease mouse model.
    Kakiyama G; Minowa K; Rodriguez-Agudo D; Martin R; Takei H; Mitamura K; Ikegawa S; Suzuki M; Nittono H; Fuchs M; Heuman DM; Zhou H; Pandak WM
    Am J Physiol Gastrointest Liver Physiol; 2022 Nov; 323(5):G488-G500. PubMed ID: 36193897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition.
    Kakiyama G; Marques D; Martin R; Takei H; Rodriguez-Agudo D; LaSalle SA; Hashiguchi T; Liu X; Green R; Erickson S; Gil G; Fuchs M; Suzuki M; Murai T; Nittono H; Hylemon PB; Zhou H; Pandak WM
    J Lipid Res; 2020 Dec; 61(12):1629-1644. PubMed ID: 33008924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease.
    Minowa K; Rodriguez-Agudo D; Suzuki M; Muto Y; Hirai S; Wang Y; Su L; Zhou H; Chen Q; Lesnefsky EJ; Mitamura K; Ikegawa S; Takei H; Nittono H; Fuchs M; Pandak WM; Kakiyama G
    J Lipid Res; 2023 May; 64(5):100363. PubMed ID: 36966904
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial oxysterol biosynthetic pathway gives evidence for CYP7B1 as controller of regulatory oxysterols.
    Kakiyama G; Marques D; Takei H; Nittono H; Erickson S; Fuchs M; Rodriguez-Agudo D; Gil G; Hylemon PB; Zhou H; Bajaj JS; Pandak WM
    J Steroid Biochem Mol Biol; 2019 May; 189():36-47. PubMed ID: 30710743
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis.
    Raselli T; Hearn T; Wyss A; Atrott K; Peter A; Frey-Wagner I; Spalinger MR; Maggio EM; Sailer AW; Schmitt J; Schreiner P; Moncsek A; Mertens J; Scharl M; Griffiths WJ; Bueter M; Geier A; Rogler G; Wang Y; Misselwitz B
    J Lipid Res; 2019 Jul; 60(7):1270-1283. PubMed ID: 31113816
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality.
    Evangelakos I; Schwinge D; Worthmann A; John C; Roeder N; Pertzborn P; Behrens J; Schramm C; Scheja L; Heeren J
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685636
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mining for Oxysterols in
    Meljon A; Crick PJ; Yutuc E; Yau JL; Seckl JR; Theofilopoulos S; Arenas E; Wang Y; Griffiths WJ
    Biomolecules; 2019 Apr; 9(4):. PubMed ID: 31013940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. StarD5 levels of expression correlate with onset and progression of steatosis and liver fibrosis.
    Kakiyama G; Minoiwa K; Bai-Kamara N; Hashiguchi T; Pandak WM; Rodriguez-Agudo D
    Am J Physiol Gastrointest Liver Physiol; 2024 Jun; 326(6):G747-G761. PubMed ID: 38591148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial Cholesterol Metabolites in a Bile Acid Synthetic Pathway Drive Nonalcoholic Fatty Liver Disease: A Revised "Two-Hit" Hypothesis.
    Kakiyama G; Rodriguez-Agudo D; Pandak WM
    Cells; 2023 May; 12(10):. PubMed ID: 37408268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease.
    Zhang H; Shen Z; Lin Y; Zhang J; Zhang Y; Liu P; Zeng H; Yu M; Chen X; Ning L; Mao X; Cen L; Yu C; Xu C
    J Biol Chem; 2020 Mar; 295(12):3891-3905. PubMed ID: 32051143
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions.
    Orlicky DJ; Libby AE; Bales ES; McMahan RH; Monks J; La Rosa FG; McManaman JL
    J Physiol; 2019 Mar; 597(6):1565-1584. PubMed ID: 30536914
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatocyte Nuclear Factor 4α Prevents the Steatosis-to-NASH Progression by Regulating p53 and Bile Acid Signaling (in mice).
    Xu Y; Zhu Y; Hu S; Xu Y; Stroup D; Pan X; Bawa FC; Chen S; Gopoju R; Yin L; Zhang Y
    Hepatology; 2021 Jun; 73(6):2251-2265. PubMed ID: 33098092
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Different effects of CYP27A1 and CYP7B1 on cognitive function: Two mouse models in comparison.
    Goikolea J; Latorre-Leal M; Tsagkogianni C; Pikkupeura S; Gulyas B; Cedazo-Minguez A; Loera-Valencia R; Björkhem I; Rodriguez Rodriguez P; Maioli S
    J Steroid Biochem Mol Biol; 2023 Nov; 234():106387. PubMed ID: 37648096
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The CH25H-CYP7B1-RORα axis of cholesterol metabolism regulates osteoarthritis.
    Choi WS; Lee G; Song WH; Koh JT; Yang J; Kwak JS; Kim HE; Kim SK; Son YO; Nam H; Jin I; Park ZY; Kim J; Park IY; Hong JI; Kim HA; Chun CH; Ryu JH; Chun JS
    Nature; 2019 Feb; 566(7743):254-258. PubMed ID: 30728500
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury.
    Wang Z; Yang X; Chen L; Zhi X; Lu H; Ning Y; Yeong J; Chen S; Yin L; Wang X; Li X
    Arch Toxicol; 2017 Jan; 91(1):271-287. PubMed ID: 27052460
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vivo and in vitro regulation of sterol 27-hydroxylase in the liver during the acute phase response. potential role of hepatocyte nuclear factor-1.
    Memon RA; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
    J Biol Chem; 2001 Aug; 276(32):30118-26. PubMed ID: 11406622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FBXW7 suppresses HMGB1-mediated innate immune signaling to attenuate hepatic inflammation and insulin resistance in a mouse model of nonalcoholic fatty liver disease.
    Zhang C; Chen F; Feng L; Shan Q; Zheng GH; Wang YJ; Lu J; Fan SH; Sun CH; Wu DM; Li MQ; Hu B; Wang QQ; Zhang ZF; Zheng YL
    Mol Med; 2019 Jun; 25(1):29. PubMed ID: 31215394
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.
    Ren S; Marques D; Redford K; Hylemon PB; Gil G; Vlahcevic ZR; Pandak WM
    Metabolism; 2003 May; 52(5):636-42. PubMed ID: 12759897
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants.
    Yantsevich AV; Dichenko YV; Mackenzie F; Mukha DV; Baranovsky AV; Gilep AA; Usanov SA; Strushkevich NV
    FEBS J; 2014 Mar; 281(6):1700-13. PubMed ID: 24491228
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disruption of the oxysterol 7alpha-hydroxylase gene in mice.
    Li-Hawkins J; Lund EG; Turley SD; Russell DW
    J Biol Chem; 2000 Jun; 275(22):16536-42. PubMed ID: 10748048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.