These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
8. Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over β-arrestin recruitment and receptor internalization. Boon K; Vanalken N; Szpakowska M; Chevigné A; Schols D; Van Loy T Cell Commun Signal; 2024 Jan; 22(1):43. PubMed ID: 38233929 [TBL] [Abstract][Full Text] [Related]
9. Loss of biased signaling at a G protein-coupled receptor in overexpressed systems. Li A; Liu S; Huang R; Ahn S; Lefkowitz RJ PLoS One; 2023; 18(3):e0283477. PubMed ID: 36961836 [TBL] [Abstract][Full Text] [Related]
10. Biased agonism as a mechanism for differential signaling by chemokine receptors. Rajagopal S; Bassoni DL; Campbell JJ; Gerard NP; Gerard C; Wehrman TS J Biol Chem; 2013 Dec; 288(49):35039-48. PubMed ID: 24145037 [TBL] [Abstract][Full Text] [Related]
11. G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β Choi M; Staus DP; Wingler LM; Ahn S; Pani B; Capel WD; Lefkowitz RJ Sci Signal; 2018 Aug; 11(544):. PubMed ID: 30131371 [TBL] [Abstract][Full Text] [Related]
12. Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N terminus in chemokine binding. Gustavsson M; Dyer DP; Zhao C; Handel TM Sci Signal; 2019 Sep; 12(598):. PubMed ID: 31506383 [TBL] [Abstract][Full Text] [Related]
13. [Biased Signaling through G Protein-coupled Receptors]. Kurose H Yakugaku Zasshi; 2022; 142(10):1091-1101. PubMed ID: 36184444 [TBL] [Abstract][Full Text] [Related]
14. Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Shao Z; Shen Q; Yao B; Mao C; Chen LN; Zhang H; Shen DD; Zhang C; Li W; Du X; Li F; Ma H; Chen ZH; Xu HE; Ying S; Zhang Y; Shen H Nat Chem Biol; 2022 Mar; 18(3):264-271. PubMed ID: 34949837 [TBL] [Abstract][Full Text] [Related]
15. Ligand-biased and probe-dependent modulation of chemokine receptor CXCR3 signaling by negative allosteric modulators. Bernat V; Brox R; Heinrich MR; Auberson YP; Tschammer N ChemMedChem; 2015 Mar; 10(3):566-74. PubMed ID: 25655398 [TBL] [Abstract][Full Text] [Related]
16. Serodolin, a β-arrestin-biased ligand of 5-HT El Khamlichi C; Reverchon F; Hervouet-Coste N; Robin E; Chopin N; Deau E; Madouri F; Guimpied C; Colas C; Menuet A; Inoue A; Bojarski AJ; Guillaumet G; Suzenet F; Reiter E; Morisset-Lopez S Proc Natl Acad Sci U S A; 2022 May; 119(21):e2118847119. PubMed ID: 35594393 [TBL] [Abstract][Full Text] [Related]
17. A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. Sanchez-Soto M; Verma RK; Willette BKA; Gonye EC; Moore AM; Moritz AE; Boateng CA; Yano H; Free RB; Shi L; Sibley DR Sci Signal; 2020 Feb; 13(617):. PubMed ID: 32019899 [TBL] [Abstract][Full Text] [Related]
18. Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression. Paradis JS; Ly S; Blondel-Tepaz É; Galan JA; Beautrait A; Scott MG; Enslen H; Marullo S; Roux PP; Bouvier M Proc Natl Acad Sci U S A; 2015 Sep; 112(37):E5160-8. PubMed ID: 26324936 [TBL] [Abstract][Full Text] [Related]