BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 36198360)

  • 1. Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
    Jiang Y; Wang T; Sheng D; Han C; Xu T; Zhang P; You W; Fan W; Zhang Z; Jin T; Duan X; Yuan X; Liu X; Zhang K; Ruan K; Shi J; Guo J; Cheng A; Yang Z
    J Biol Chem; 2022 Nov; 298(11):102561. PubMed ID: 36198360
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
    Vander Heiden MG; Locasale JW; Swanson KD; Sharfi H; Heffron GJ; Amador-Noguez D; Christofk HR; Wagner G; Rabinowitz JD; Asara JM; Cantley LC
    Science; 2010 Sep; 329(5998):1492-9. PubMed ID: 20847263
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcription factor LHX9 (LIM Homeobox 9) enhances pyruvate kinase PKM2 activity to induce glycolytic metabolic reprogramming in cancer stem cells, promoting gastric cancer progression.
    Zhao H; Jiang R; Feng Z; Wang X; Zhang C
    J Transl Med; 2023 Nov; 21(1):833. PubMed ID: 37980488
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase.
    Mor I; Carlessi R; Ast T; Feinstein E; Kimchi A
    Oncogene; 2012 Feb; 31(6):683-93. PubMed ID: 21725354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence That Does Not Support Pyruvate Kinase M2 (PKM2)-catalyzed Reaction as a Rate-limiting Step in Cancer Cell Glycolysis.
    Xie J; Dai C; Hu X
    J Biol Chem; 2016 Apr; 291(17):8987-99. PubMed ID: 26917721
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Screening Kinase-Dependent Phosphorylation of Key Metabolic Reprogramming Regulators.
    Kaci FN; Lepore A; Papa S; Bubici C
    Methods Mol Biol; 2023; 2675():205-218. PubMed ID: 37258766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect.
    Cheng A; Zhang P; Wang B; Yang D; Duan X; Jiang Y; Xu T; Jiang Y; Shi J; Ding C; Wu G; Sang Z; Wu Q; Wang H; Wu M; Zhang Z; Pan X; Pan YY; Gao P; Zhang H; Zhou CZ; Guo J; Yang Z
    Nat Commun; 2019 Dec; 10(1):5566. PubMed ID: 31804482
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
    Iqbal MA; Siddiqui FA; Gupta V; Chattopadhyay S; Gopinath P; Kumar B; Manvati S; Chaman N; Bamezai RN
    Mol Cancer; 2013 Jul; 12():72. PubMed ID: 23837608
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple functions of pyruvate kinase M2 in various cell types.
    Lee YB; Min JK; Kim JG; Cap KC; Islam R; Hossain AJ; Dogsom O; Hamza A; Mahmud S; Choi DR; Kim YS; Koh YH; Kim HA; Chung WS; Suh SW; Park JB
    J Cell Physiol; 2022 Jan; 237(1):128-148. PubMed ID: 34311499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells.
    Yu Z; Zhao X; Huang L; Zhang T; Yang F; Xie L; Song S; Miao P; Zhao L; Sun X; Liu J; Huang G
    J Biol Chem; 2013 Dec; 288(49):35406-16. PubMed ID: 24142698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pyruvate kinase M2: multiple faces for conferring benefits on cancer cells.
    Tamada M; Suematsu M; Saya H
    Clin Cancer Res; 2012 Oct; 18(20):5554-61. PubMed ID: 23071357
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle.
    Benzarti M; Neises L; Oudin A; Krötz C; Viry E; Gargiulo E; Pulido C; Schmoetten M; Pozdeev V; Lorenz NI; Ronellenfitsch MW; Sumpton D; Warmoes M; Jaeger C; Lesur A; Becker B; Moussay E; Paggetti J; Niclou SP; Letellier E; Meiser J
    Cell Rep; 2024 Mar; 43(3):113868. PubMed ID: 38421868
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
    Chaneton B; Hillmann P; Zheng L; Martin ACL; Maddocks ODK; Chokkathukalam A; Coyle JE; Jankevics A; Holding FP; Vousden KH; Frezza C; O'Reilly M; Gottlieb E
    Nature; 2012 Nov; 491(7424):458-462. PubMed ID: 23064226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites.
    Yu Q; Tong C; Luo M; Xue X; Mei Q; Ma L; Yu X; Mao W; Kong L; Yu X; Li S
    PLoS One; 2017; 12(4):e0175576. PubMed ID: 28426732
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
    Li M; Lu H; Wang X; Duan C; Zhu X; Zhang Y; Ge X; Ji F; Wang X; Su J; Zhang D
    Mol Immunol; 2021 Dec; 140():250-266. PubMed ID: 34798593
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment.
    Sarfraz I; Rasul A; Jabeen F; Sultana T; Adem Ş
    Molecules; 2022 Oct; 27(20):. PubMed ID: 36296707
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
    Chiavarina B; Whitaker-Menezes D; Martinez-Outschoorn UE; Witkiewicz AK; Birbe R; Howell A; Pestell RG; Smith J; Daniel R; Sotgia F; Lisanti MP
    Cancer Biol Ther; 2011 Dec; 12(12):1101-13. PubMed ID: 22236875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
    Nandi S; Razzaghi M; Srivastava D; Dey M
    J Biol Chem; 2020 Dec; 295(51):17425-17440. PubMed ID: 33453989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cancer metabolism control by natural products: Pyruvate kinase M2 targeting therapeutics.
    El-Far AH; Al Jaouni SK; Li X; Fu J
    Phytother Res; 2022 Aug; 36(8):3181-3201. PubMed ID: 35794729
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.
    Ye J; Mancuso A; Tong X; Ward PS; Fan J; Rabinowitz JD; Thompson CB
    Proc Natl Acad Sci U S A; 2012 May; 109(18):6904-9. PubMed ID: 22509023
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.