BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 36198360)

  • 21. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
    Sun Q; Chen X; Ma J; Peng H; Wang F; Zha X; Wang Y; Jing Y; Yang H; Chen R; Chang L; Zhang Y; Goto J; Onda H; Chen T; Wang MR; Lu Y; You H; Kwiatkowski D; Zhang H
    Proc Natl Acad Sci U S A; 2011 Mar; 108(10):4129-34. PubMed ID: 21325052
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration.
    Rajala A; Wang Y; Soni K; Rajala RVS
    Cell Death Dis; 2018 Jul; 9(7):737. PubMed ID: 29970877
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
    Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
    Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
    [TBL] [Abstract][Full Text] [Related]  

  • 24. GTPBP4 promotes hepatocellular carcinoma progression and metastasis via the PKM2 dependent glucose metabolism.
    Zhou Q; Yin Y; Yu M; Gao D; Sun J; Yang Z; Weng J; Chen W; Atyah M; Shen Y; Ye Q; Li CW; Hung MC; Dong Q; Zhou C; Ren N
    Redox Biol; 2022 Oct; 56():102458. PubMed ID: 36116159
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma.
    Wu S; Cao R; Tao B; Wu P; Peng C; Gao H; Liang J; Yang W
    Adv Sci (Weinh); 2022 Mar; 9(8):e2104055. PubMed ID: 35048565
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pyruvate kinase: Function, regulation and role in cancer.
    Israelsen WJ; Vander Heiden MG
    Semin Cell Dev Biol; 2015 Jul; 43():43-51. PubMed ID: 26277545
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase.
    Gao X; Wang H; Yang JJ; Liu X; Liu ZR
    Mol Cell; 2012 Mar; 45(5):598-609. PubMed ID: 22306293
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mediation of PKM2-dependent glycolytic and non-glycolytic pathways by ENO2 in head and neck cancer development.
    Gao L; Yang F; Tang D; Xu Z; Tang Y; Yang D; Sun D; Chen Z; Teng Y
    J Exp Clin Cancer Res; 2023 Jan; 42(1):1. PubMed ID: 36588153
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Pyruvate kinase M2 regulates fibrosis development and progression by controlling glycine auxotrophy in myofibroblasts.
    Satyanarayana G; Turaga RC; Sharma M; Wang S; Mishra F; Peng G; Deng X; Yang J; Liu ZR
    Theranostics; 2021; 11(19):9331-9341. PubMed ID: 34646373
    [No Abstract]   [Full Text] [Related]  

  • 30. A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy.
    Yang GJ; Wu J; Leung CH; Ma DL; Chen J
    Int J Biol Macromol; 2021 Dec; 193(Pt B):1499-1506. PubMed ID: 34740687
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells.
    Mazurek S
    Int J Biochem Cell Biol; 2011 Jul; 43(7):969-80. PubMed ID: 20156581
    [TBL] [Abstract][Full Text] [Related]  

  • 32. IGF1 regulates PKM2 function through Akt phosphorylation.
    Salani B; Ravera S; Amaro A; Salis A; Passalacqua M; Millo E; Damonte G; Marini C; Pfeffer U; Sambuceti G; Cordera R; Maggi D
    Cell Cycle; 2015; 14(10):1559-67. PubMed ID: 25790097
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia.
    Handzlik MK; Tooth DJ; Constantin-Teodosiu D; Greenhaff PL; Cole MA
    Biosci Rep; 2021 Jun; 41(6):. PubMed ID: 33973628
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease.
    Shirai T; Nazarewicz RR; Wallis BB; Yanes RE; Watanabe R; Hilhorst M; Tian L; Harrison DG; Giacomini JC; Assimes TL; Goronzy JJ; Weyand CM
    J Exp Med; 2016 Mar; 213(3):337-54. PubMed ID: 26926996
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pyruvate kinase M2 and cancer: an updated assessment.
    Iqbal MA; Gupta V; Gopinath P; Mazurek S; Bamezai RN
    FEBS Lett; 2014 Aug; 588(16):2685-92. PubMed ID: 24747424
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
    Anastasiou D; Yu Y; Israelsen WJ; Jiang JK; Boxer MB; Hong BS; Tempel W; Dimov S; Shen M; Jha A; Yang H; Mattaini KR; Metallo CM; Fiske BP; Courtney KD; Malstrom S; Khan TM; Kung C; Skoumbourdis AP; Veith H; Southall N; Walsh MJ; Brimacombe KR; Leister W; Lunt SY; Johnson ZR; Yen KE; Kunii K; Davidson SM; Christofk HR; Austin CP; Inglese J; Harris MH; Asara JM; Stephanopoulos G; Salituro FG; Jin S; Dang L; Auld DS; Park HW; Cantley LC; Thomas CJ; Vander Heiden MG
    Nat Chem Biol; 2012 Oct; 8(10):839-47. PubMed ID: 22922757
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils.
    Toller-Kawahisa JE; Hiroki CH; Silva CMS; Nascimento DC; Públio GA; Martins TV; Damasceno LEA; Veras FP; Viacava PR; Sukesada FY; Day EA; Zotta A; Ryan TAJ; Moreira da Silva R; Cunha TM; Lopes NP; Cunha FQ; O'Neill LAJ; Alves-Filho JC
    Nat Commun; 2023 Jul; 14(1):4280. PubMed ID: 37460614
    [TBL] [Abstract][Full Text] [Related]  

  • 38. MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.
    Kosugi M; Ahmad R; Alam M; Uchida Y; Kufe D
    PLoS One; 2011; 6(11):e28234. PubMed ID: 22140559
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.
    Bertelsen LB; Hansen ESS; Sadowski T; Ruf S; Laustsen C
    NMR Biomed; 2021 Nov; 34(11):e4583. PubMed ID: 34240478
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer.
    Chao TK; Huang TS; Liao YP; Huang RL; Su PH; Shen HY; Lai HC; Wang YC
    PLoS One; 2017; 12(7):e0182166. PubMed ID: 28753677
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.