BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 36202993)

  • 21. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro.
    You M; Varona-Santos J; Singh S; Robbins DJ; Savaraj N; Nguyen DM
    J Thorac Cardiovasc Surg; 2014 Jan; 147(1):508-16. PubMed ID: 24094913
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Dual pathways for induction of wingless expression by protein kinase A and Hedgehog in Drosophila embryos.
    Ohlmeyer JT; Kalderon D
    Genes Dev; 1997 Sep; 11(17):2250-8. PubMed ID: 9303540
    [TBL] [Abstract][Full Text] [Related]  

  • 23. PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation.
    Jia H; Liu Y; Yan W; Jia J
    Development; 2009 Jan; 136(2):307-16. PubMed ID: 19088085
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Decoding the phosphorylation code in Hedgehog signal transduction.
    Chen Y; Jiang J
    Cell Res; 2013 Feb; 23(2):186-200. PubMed ID: 23337587
    [TBL] [Abstract][Full Text] [Related]  

  • 25. G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila.
    Chen Y; Li S; Tong C; Zhao Y; Wang B; Liu Y; Jia J; Jiang J
    Genes Dev; 2010 Sep; 24(18):2054-67. PubMed ID: 20844016
    [TBL] [Abstract][Full Text] [Related]  

  • 26. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
    Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F
    Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity.
    Maier D; Cheng S; Faubert D; Hipfner DR
    PLoS Genet; 2014 Jul; 10(7):e1004399. PubMed ID: 25009998
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway.
    Ma G; Li S; Han Y; Li S; Yue T; Wang B; Jiang J
    Dev Cell; 2016 Nov; 39(4):438-451. PubMed ID: 27746045
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mechanisms of Smoothened Regulation in Hedgehog Signaling.
    Zhang J; Liu Z; Jia J
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440907
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation.
    Shi Q; Li S; Jia J; Jiang J
    Development; 2011 Oct; 138(19):4219-31. PubMed ID: 21852395
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins.
    Polizio AH; Chinchilla P; Chen X; Manning DR; Riobo NA
    Sci Signal; 2011 Nov; 4(200):pt7. PubMed ID: 22114142
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.
    Ruel L; Gallet A; Raisin S; Truchi A; Staccini-Lavenant L; Cervantes A; Thérond PP
    Development; 2007 Oct; 134(20):3677-89. PubMed ID: 17881487
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila.
    Nakano Y; Nystedt S; Shivdasani AA; Strutt H; Thomas C; Ingham PW
    Mech Dev; 2004 Jun; 121(6):507-18. PubMed ID: 15172682
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The last 59 amino acids of Smoothened cytoplasmic tail directly bind the protein kinase Fused and negatively regulate the Hedgehog pathway.
    Malpel S; Claret S; Sanial M; Brigui A; Piolot T; Daviet L; Martin-Lannerée S; Plessis A
    Dev Biol; 2007 Mar; 303(1):121-33. PubMed ID: 17182028
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner.
    Fan J; Liu Y; Jia J
    Dev Biol; 2012 Jun; 366(2):172-84. PubMed ID: 22537496
    [TBL] [Abstract][Full Text] [Related]  

  • 36. An intracellular activation of Smoothened that is independent of Hedgehog stimulation in
    Jiang K; Liu Y; Zhang J; Jia J
    J Cell Sci; 2018 Jan; 131(1):. PubMed ID: 29142103
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Transducing the Hedgehog signal across the plasma membrane.
    Zhao Y; Tong C; Jiang J
    Fly (Austin); 2007; 1(6):333-6. PubMed ID: 18820483
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Cell-Based Assays for Smoothened Ubiquitination and Sumoylation.
    Han Y; Jiang J
    Methods Mol Biol; 2022; 2374():139-147. PubMed ID: 34562249
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction.
    Zhu AJ; Zheng L; Suyama K; Scott MP
    Genes Dev; 2003 May; 17(10):1240-52. PubMed ID: 12730121
    [TBL] [Abstract][Full Text] [Related]  

  • 40. GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli.
    Zhan X; Wang J; Liu Y; Peng Y; Tan W
    Mol Cancer; 2014 Jan; 13():4. PubMed ID: 24393163
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.