146 related articles for article (PubMed ID: 36206451)
1. Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors.
Asberry AM; Cai X; Deng X; Santiago U; Liu S; Sims HS; Liang W; Xu X; Wan J; Jiang W; Camacho CJ; Dai M; Hu CD
J Med Chem; 2022 Oct; 65(20):13793-13812. PubMed ID: 36206451
[TBL] [Abstract][Full Text] [Related]
2. Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression.
Saha K; Eckert RL
J Biol Chem; 2015 May; 290(21):13521-30. PubMed ID: 25851901
[TBL] [Abstract][Full Text] [Related]
3. Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.
Burgos ES; Wilczek C; Onikubo T; Bonanno JB; Jansong J; Reimer U; Shechter D
J Biol Chem; 2015 Apr; 290(15):9674-89. PubMed ID: 25713080
[TBL] [Abstract][Full Text] [Related]
4. MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.
Saha K; Adhikary G; Eckert RL
J Invest Dermatol; 2016 Jan; 136(1):214-224. PubMed ID: 26763441
[TBL] [Abstract][Full Text] [Related]
5. A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
Chen H; Lorton B; Gupta V; Shechter D
Oncogene; 2017 Jan; 36(3):373-386. PubMed ID: 27270440
[TBL] [Abstract][Full Text] [Related]
6. MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex.
Abe Y; Suzuki Y; Kawamura K; Tanaka N
Commun Biol; 2019; 2():23. PubMed ID: 30675521
[TBL] [Abstract][Full Text] [Related]
7. The Structure and Function of the PRMT5:MEP50 Complex.
Antonysamy S
Subcell Biochem; 2017; 83():185-194. PubMed ID: 28271477
[TBL] [Abstract][Full Text] [Related]
8. Sulforaphane inhibits PRMT5 and MEP50 function to suppress the mesothelioma cancer cell phenotype.
Ezeka G; Adhikary G; Kandasamy S; Friedberg JS; Eckert RL
Mol Carcinog; 2021 Jul; 60(7):429-439. PubMed ID: 33872411
[TBL] [Abstract][Full Text] [Related]
9. Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods.
Zhu K; Jiang CS; Hu J; Liu X; Yan X; Tao H; Luo C; Zhang H
Biochem Biophys Res Commun; 2018 Jan; 495(1):721-727. PubMed ID: 29154828
[TBL] [Abstract][Full Text] [Related]
10. Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors.
Krzyzanowski A; Esser LM; Willaume A; Prudent R; Peter C; 't Hart P; Waldmann H
J Med Chem; 2022 Nov; 65(22):15300-15311. PubMed ID: 36378254
[TBL] [Abstract][Full Text] [Related]
11. Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex.
Krzyzanowski A; Gasper R; Adihou H; Hart P'; Waldmann H
Chembiochem; 2021 Jun; 22(11):1908-1914. PubMed ID: 33624332
[TBL] [Abstract][Full Text] [Related]
12. Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis.
Wei TY; Hsia JY; Chiu SC; Su LJ; Juan CC; Lee YC; Chen JM; Chou HY; Huang JY; Huang HM; Yu CT
Cell Signal; 2014 Dec; 26(12):2940-50. PubMed ID: 25277535
[TBL] [Abstract][Full Text] [Related]
13. Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells.
Chatterjee B; Ghosh K; Suresh L; Kanade SR
Mol Cell Biochem; 2019 May; 455(1-2):73-90. PubMed ID: 30392062
[TBL] [Abstract][Full Text] [Related]
14. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.
Wang M; Fuhrmann J; Thompson PR
Biochemistry; 2014 Dec; 53(50):7884-92. PubMed ID: 25485739
[TBL] [Abstract][Full Text] [Related]
15. Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.
Ho MC; Wilczek C; Bonanno JB; Xing L; Seznec J; Matsui T; Carter LG; Onikubo T; Kumar PR; Chan MK; Brenowitz M; Cheng RH; Reimer U; Almo SC; Shechter D
PLoS One; 2013; 8(2):e57008. PubMed ID: 23451136
[TBL] [Abstract][Full Text] [Related]
16. Expression of mep50 in adult and embryos of medaka fish (Oryzias latipes).
Cheng N; Guo M; Chang P; Zhang X; Zhang R; Qi C; Zhong X; Zhou Q; Zhao H
Fish Physiol Biochem; 2016 Jun; 42(3):1053-61. PubMed ID: 26749004
[TBL] [Abstract][Full Text] [Related]
17. The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
Stopa N; Krebs JE; Shechter D
Cell Mol Life Sci; 2015 Jun; 72(11):2041-59. PubMed ID: 25662273
[TBL] [Abstract][Full Text] [Related]
18. Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.
Saha K; Fisher ML; Adhikary G; Grun D; Eckert RL
Carcinogenesis; 2017 Aug; 38(8):827-836. PubMed ID: 28854561
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2
Ichikawa T; Suekane A; Nakahata S; Iha H; Shimoda K; Murakami T; Morishita K
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474089
[TBL] [Abstract][Full Text] [Related]
20. Lead induces the up-regulation of the protein arginine methyltransferase 5 possibly by its promoter demethylation.
Ghosh K; Chatterjee B; Kanade SR
Biochem J; 2018 Aug; 475(16):2653-2666. PubMed ID: 30054435
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
