These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 36207292)

  • 21. Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.
    Doyle JJ; Maios C; Vrancx C; Duhaime S; Chitramuthu B; Bennett HPJ; Bateman A; Parker JA
    Proc Natl Acad Sci U S A; 2021 Jun; 118(25):. PubMed ID: 34140407
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations.
    Marian OC; Teo JD; Lee JY; Song H; Kwok JB; Landin-Romero R; Halliday G; Don AS
    Acta Neuropathol Commun; 2023 Mar; 11(1):52. PubMed ID: 36967384
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients.
    Valdez C; Wong YC; Schwake M; Bu G; Wszolek ZK; Krainc D
    Hum Mol Genet; 2017 Dec; 26(24):4861-4872. PubMed ID: 29036611
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential regulation of progranulin derived granulin peptides.
    Zhang T; Du H; Santos MN; Wu X; Pagan MD; Trigiani LJ; Nishimura N; Reinheckel T; Hu F
    Mol Neurodegener; 2022 Feb; 17(1):15. PubMed ID: 35120524
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice.
    Filiano AJ; Martens LH; Young AH; Warmus BA; Zhou P; Diaz-Ramirez G; Jiao J; Zhang Z; Huang EJ; Gao FB; Farese RV; Roberson ED
    J Neurosci; 2013 Mar; 33(12):5352-61. PubMed ID: 23516300
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Progranulin deficiency results in sex-dependent alterations in microglia in response to demyelination.
    Zhang T; Feng T; Wu K; Guo J; Nana AL; Yang G; Seeley WW; Hu F
    Acta Neuropathol; 2023 Jul; 146(1):97-119. PubMed ID: 37120788
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
    Frew J; Baradaran-Heravi A; Balgi AD; Wu X; Yan TD; Arns S; Shidmoossavee FS; Tan J; Jaquith JB; Jansen-West KR; Lynn FC; Gao FB; Petrucelli L; Feldman HH; Mackenzie IR; Roberge M; Nygaard HB
    Mol Neurodegener; 2020 Mar; 15(1):21. PubMed ID: 32178712
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Progranulin as a therapeutic target in neurodegenerative diseases.
    Rhinn H; Tatton N; McCaughey S; Kurnellas M; Rosenthal A
    Trends Pharmacol Sci; 2022 Aug; 43(8):641-652. PubMed ID: 35039149
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The lysosomal function of progranulin, a guardian against neurodegeneration.
    Paushter DH; Du H; Feng T; Hu F
    Acta Neuropathol; 2018 Jul; 136(1):1-17. PubMed ID: 29744576
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Granulins rescue inflammation, lysosome dysfunction, and neuropathology in a mouse model of progranulin deficiency.
    Root J; Mendsaikhan A; Nandy S; Taylor G; Wang M; Araujo LT; Merino P; Ryu D; Holler C; Thompson BM; Astarita G; Blain JF; Kukar T
    bioRxiv; 2023 Apr; ():. PubMed ID: 37131734
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia.
    Kurnellas M; Mitra A; Schwabe T; Paul R; Arrant AE; Roberson ED; Ward M; Yeh F; Long H; Rosenthal A
    J Transl Med; 2023 Jun; 21(1):387. PubMed ID: 37322482
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
    Götzl JK; Colombo AV; Fellerer K; Reifschneider A; Werner G; Tahirovic S; Haass C; Capell A
    Mol Neurodegener; 2018 Sep; 13(1):48. PubMed ID: 30180904
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway.
    Dong T; Tejwani L; Jung Y; Kokubu H; Luttik K; Driessen TM; Lim J
    JCI Insight; 2021 Nov; 6(22):. PubMed ID: 34618685
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.
    Alquézar C; de la Encarnación A; Moreno F; López de Munain A; Martín-Requero Á
    J Psychiatry Neurosci; 2016 Jun; 41(4):225-39. PubMed ID: 26624524
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
    Santos MN; Paushter DH; Zhang T; Wu X; Feng T; Lou J; Du H; Becker SM; Fragoza R; Yu H; Hu F
    J Biol Chem; 2022 Sep; 298(9):102348. PubMed ID: 35933009
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviors.
    Wang J; Lai S; Zhou T; Xia Z; Li W; Sha W; Liu J; Chen Y
    J Neuroinflammation; 2022 Dec; 19(1):318. PubMed ID: 36581897
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Approaches to develop therapeutics to treat frontotemporal dementia.
    Elia LP; Reisine T; Alijagic A; Finkbeiner S
    Neuropharmacology; 2020 Apr; 166():107948. PubMed ID: 31962288
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Microglial Progranulin: Involvement in Alzheimer's Disease and Neurodegenerative Diseases.
    Mendsaikhan A; Tooyama I; Walker DG
    Cells; 2019 Mar; 8(3):. PubMed ID: 30862089
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.
    Hu F; Padukkavidana T; Vægter CB; Brady OA; Zheng Y; Mackenzie IR; Feldman HH; Nykjaer A; Strittmatter SM
    Neuron; 2010 Nov; 68(4):654-67. PubMed ID: 21092856
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial.
    Ljubenkov PA; Edwards L; Iaccarino L; La Joie R; Rojas JC; Koestler M; Harris B; Boeve BF; Borroni B; van Swieten JC; Grossman M; Pasquier F; Frisoni GB; Mummery CJ; Vandenberghe R; Le Ber I; Hannequin D; McGinnis SM; Auriacombe S; Onofrj M; Goodman IJ; Riordan HJ; Wisniewski G; Hesterman J; Marek K; Haynes BA; Patzke H; Koenig G; Hilt D; Moebius H; Boxer AL
    JAMA Netw Open; 2021 Sep; 4(9):e2125584. PubMed ID: 34559230
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.