BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 36216898)

  • 1. Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16/RARα.
    Wang QQ; Hussain L; Yu PH; Yang C; Zhu CY; Ma YF; Wang SC; Yang T; Kang YY; Yu WJ; Maimaitiyiming Y; Naranmandura H
    Acta Pharmacol Sin; 2023 Apr; 44(4):822-831. PubMed ID: 36216898
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα.
    Dai B; Wang F; Wang Y; Zhu J; Li Y; Zhang T; Zhao L; Wang L; Gao W; Li J; Zhu H; Li K; Hu J
    Cell Death Differ; 2023 May; 30(5):1320-1333. PubMed ID: 36894687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ZBTB16-RARα-Positive Atypical Promyelocytic Leukemia: A Case Report.
    Pardo Gambarte L; Franganillo Suárez A; Cornago Navascués J; Soto de Ozaeta C; Blas López C; Atance Pasarisas M; Salgado Sánchez RN; Serrano Del Castillo C; Mata Serna R; Velasco Rodríguez D; López-Lorenzo JL; Llamas-Sillero P; Solán Blanco L
    Medicina (Kaunas); 2022 Apr; 58(4):. PubMed ID: 35454359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hyperthermia Selectively Destabilizes Oncogenic Fusion Proteins.
    Maimaitiyiming Y; Wang QQ; Yang C; Ogra Y; Lou Y; Smith CA; Hussain L; Shao YM; Lin J; Liu J; Wang L; Zhu Y; Lou H; Huang Y; Li X; Chang KJ; Chen H; Li H; Huang Y; Tse E; Sun J; Bu N; Chiou SH; Zhang YF; Hua HY; Ma LY; Huang P; Ge MH; Cao FL; Cheng X; Sun H; Zhou J; Vasliou V; Xu P; Jin J; Bjorklund M; Zhu HH; Hsu CH; Naranmandura H
    Blood Cancer Discov; 2021 Jul; 2(4):388-401. PubMed ID: 34661159
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.
    Guidez F; Ivins S; Zhu J; Söderström M; Waxman S; Zelent A
    Blood; 1998 Apr; 91(8):2634-42. PubMed ID: 9531570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acute promyelocytic leukemia and variant fusion proteins: PLZF-RARα fusion protein at a glance.
    Hussain L; Maimaitiyiming Y; Islam K; Naranmandura H
    Semin Oncol; 2019 Apr; 46(2):133-144. PubMed ID: 31126665
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational profile of ZBTB16-RARA-positive acute myeloid leukemia.
    Fabiani E; Cicconi L; Nardozza AM; Cristiano A; Rossi M; Ottone T; Falconi G; Divona M; Testi AM; Annibali O; Castelli R; Lazarevic V; Rego E; Montesinos P; Esteve J; Venditti A; Della Porta M; Arcese W; Lo-Coco F; Voso MT
    Cancer Med; 2021 Jun; 10(12):3839-3847. PubMed ID: 34042280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation.
    Jiao B; Ren ZH; Liu P; Chen LJ; Shi JY; Dong Y; Ablain J; Shi L; Gao L; Hu JP; Ren RB; de Thé H; Chen Z; Chen SJ
    Proc Natl Acad Sci U S A; 2013 Feb; 110(9):3495-500. PubMed ID: 23382200
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Acute promyelocytic leukemia: state-of-the-art management].
    Asou N
    Rinsho Ketsueki; 2018; 59(6):725-734. PubMed ID: 29973452
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PML-RARalpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia.
    Ohnishi K
    Int J Clin Oncol; 2007 Oct; 12(5):313-7. PubMed ID: 17929112
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The clinically relevant CHK1 inhibitor MK-8776 induces the degradation of the oncogenic protein PML-RARα and overcomes ATRA resistance in acute promyelocytic leukemia cells.
    Franza M; Albanesi J; Mancini B; Pennisi R; Leone S; Acconcia F; Bianchi F; di Masi A
    Biochem Pharmacol; 2023 Aug; 214():115675. PubMed ID: 37406967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PRMT5-mediated RNF4 methylation promotes therapeutic resistance of APL cells to As
    Huang X; Yang Y; Zhu D; Zhao Y; Wei M; Li K; Zhu HH; Zheng X
    Cell Mol Life Sci; 2022 May; 79(6):319. PubMed ID: 35622143
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mechanisms of the antileukemia activities of retinoid and arsenic.
    Nitto T; Sawaki K
    J Pharmacol Sci; 2014; 126(3):179-85. PubMed ID: 25319615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The PML-RARalpha fusion protein and targeted therapy for acute promyelocytic leukemia.
    Jing Y
    Leuk Lymphoma; 2004 Apr; 45(4):639-48. PubMed ID: 15160934
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phenylarsine Oxide Can Induce Degradation of PLZF-RARα Variant Fusion Protein of Acute Promyelocytic Leukemia.
    Hussain L; Maimaitiyiming Y; Su L; Wang QQ; Naranmandura H
    Chem Res Toxicol; 2019 Apr; 32(4):548-550. PubMed ID: 30869512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acute promyelocytic leukemia with a PLZF-RARalpha fusion protein.
    Jansen JH; Löwenberg B
    Semin Hematol; 2001 Jan; 38(1):37-41. PubMed ID: 11172538
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RXRα ligand Z-10 induces PML-RARα cleavage and APL cell apoptosis through disrupting PML-RARα/RXRα complex in a cAMP-independent manner.
    Xu L; Zeng Z; Zhang W; Ren G; Ling X; Huang F; Xie P; Su Y; Zhang XK; Zhou H
    Oncotarget; 2017 Feb; 8(7):12311-12322. PubMed ID: 28129653
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient.
    Koken MH; Daniel MT; Gianni M; Zelent A; Licht J; Buzyn A; Minard P; Degos L; Varet B; de Thé H
    Oncogene; 1999 Jan; 18(4):1113-8. PubMed ID: 10023688
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/Rarα Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: in Vitro and in Vivo Studies.
    Wu D; Shao K; Zhou Q; Sun J; Wang Z; Yan F; Liu T; Wu X; Ye B; Huang H; Zhou Y
    Cell Physiol Biochem; 2018; 48(6):2286-2301. PubMed ID: 30114705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic Leukemia Eradication by Combined Treatment with Retinoic Acid and HIF Inhibition by EZN-2208 (PEG-SN38) in Preclinical Models of PML-RARα and PLZF-RARα-Driven Leukemia.
    Coltella N; Valsecchi R; Ponente M; Ponzoni M; Bernardi R
    Clin Cancer Res; 2015 Aug; 21(16):3685-94. PubMed ID: 25931453
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.