BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 36217034)

  • 1. The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
    Zhang CS; Li M; Wang Y; Li X; Zong Y; Long S; Zhang M; Feng JW; Wei X; Liu YH; Zhang B; Wu J; Zhang C; Lian W; Ma T; Tian X; Qu Q; Yu Y; Xiong J; Liu DT; Wu Z; Zhu M; Xie C; Wu Y; Xu Z; Yang C; Chen J; Huang G; He Q; Huang X; Zhang L; Sun X; Liu Q; Ghafoor A; Gui F; Zheng K; Wang W; Wang ZC; Yu Y; Zhao Q; Lin SY; Wang ZX; Piao HL; Deng X; Lin SC
    Nat Metab; 2022 Oct; 4(10):1369-1401. PubMed ID: 36217034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
    Li M; Zhang CS; Zong Y; Feng JW; Ma T; Hu M; Lin Z; Li X; Xie C; Wu Y; Jiang D; Li Y; Zhang C; Tian X; Wang W; Yang Y; Chen J; Cui J; Wu YQ; Chen X; Liu QF; Wu J; Lin SY; Ye Z; Liu Y; Piao HL; Yu L; Zhou Z; Xie XS; Hardie DG; Lin SC
    Cell Metab; 2019 Sep; 30(3):508-524.e12. PubMed ID: 31204282
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
    Zhang CS; Hawley SA; Zong Y; Li M; Wang Z; Gray A; Ma T; Cui J; Feng JW; Zhu M; Wu YQ; Li TY; Ye Z; Lin SY; Yin H; Piao HL; Hardie DG; Lin SC
    Nature; 2017 Aug; 548(7665):112-116. PubMed ID: 28723898
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AMPK: Sensing Glucose as well as Cellular Energy Status.
    Lin SC; Hardie DG
    Cell Metab; 2018 Feb; 27(2):299-313. PubMed ID: 29153408
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
    Ma T; Tian X; Zhang B; Li M; Wang Y; Yang C; Wu J; Wei X; Qu Q; Yu Y; Long S; Feng JW; Li C; Zhang C; Xie C; Wu Y; Xu Z; Chen J; Yu Y; Huang X; He Y; Yao L; Zhang L; Zhu M; Wang W; Wang ZC; Zhang M; Bao Y; Jia W; Lin SY; Ye Z; Piao HL; Deng X; Zhang CS; Lin SC
    Nature; 2022 Mar; 603(7899):159-165. PubMed ID: 35197629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1.
    Li M; Zhang CS; Feng JW; Wei X; Zhang C; Xie C; Wu Y; Hawley SA; Atrih A; Lamont DJ; Wang Z; Piao HL; Hardie DG; Lin SC
    Cell Res; 2021 Apr; 31(4):478-481. PubMed ID: 33349646
    [No Abstract]   [Full Text] [Related]  

  • 7. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms.
    Nwadike C; Williamson LE; Gallagher LE; Guan JL; Chan EYW
    Mol Cell Biol; 2018 May; 38(10):. PubMed ID: 29507183
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
    Liu H; Ding J; Köhnlein K; Urban N; Ori A; Villavicencio-Lorini P; Walentek P; Klotz LO; Hollemann T; Pfirrmann T
    Autophagy; 2020 Sep; 16(9):1618-1634. PubMed ID: 31795790
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glucose starvation increases V-ATPase assembly and activity in mammalian cells through AMP kinase and phosphatidylinositide 3-kinase/Akt signaling.
    McGuire CM; Forgac M
    J Biol Chem; 2018 Jun; 293(23):9113-9123. PubMed ID: 29540478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Starvation-induced lysosomal degradation of aldolase B requires glutamine 111 in a signal sequence for chaperone-mediated transport.
    Susan PP; Dunn WA
    J Cell Physiol; 2001 Apr; 187(1):48-58. PubMed ID: 11241348
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitinated aldolase B accumulates during starvation-induced lysosomal proteolysis.
    Lenk SE; Susan PP; Hickson I; Jasionowski T; Dunn WA
    J Cell Physiol; 1999 Jan; 178(1):17-27. PubMed ID: 9886486
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The lysosomal v-ATPase-Ragulator complex is a common activator for AMPK and mTORC1, acting as a switch between catabolism and anabolism.
    Zhang CS; Jiang B; Li M; Zhu M; Peng Y; Zhang YL; Wu YQ; Li TY; Liang Y; Lu Z; Lian G; Liu Q; Guo H; Yin Z; Ye Z; Han J; Wu JW; Yin H; Lin SY; Lin SC
    Cell Metab; 2014 Sep; 20(3):526-40. PubMed ID: 25002183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methods to Study Lysosomal AMPK Activation.
    Zhang CS; Li M; Lin SC
    Methods Enzymol; 2017; 587():465-480. PubMed ID: 28253973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis.
    Fernandez-Mosquera L; Yambire KF; Couto R; Pereyra L; Pabis K; Ponsford AH; Diogo CV; Stagi M; Milosevic I; Raimundo N
    Autophagy; 2019 Sep; 15(9):1572-1591. PubMed ID: 30917721
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginsenoside Rg1 protects H9c2 cells against nutritional stress-induced injury via aldolase /AMPK/PINK1 signalling.
    Xu Z; Li C; Liu Q; Yang H; Li P
    J Cell Biochem; 2019 Oct; 120(10):18388-18397. PubMed ID: 31209925
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modification of rat liver fructose biphosphate aldolase by lysosomal proteinases.
    Katunuma N; Kominami E; Hashida S; Wakamatsu N
    Adv Enzyme Regul; 1982; 20():337-50. PubMed ID: 7051771
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metformin extends
    Chen J; Ou Y; Li Y; Hu S; Shao LW; Liu Y
    Elife; 2017 Oct; 6():. PubMed ID: 29027899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AKT Ser/Thr kinase increases V-ATPase-dependent lysosomal acidification in response to amino acid starvation in mammalian cells.
    Collins MP; Stransky LA; Forgac M
    J Biol Chem; 2020 Jul; 295(28):9433-9444. PubMed ID: 32409581
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance.
    Gugliucci A
    Med Hypotheses; 2016 Aug; 93():87-92. PubMed ID: 27372863
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans.
    Banerjee J; Bruckbauer A; Zemel MB
    Metabolism; 2016 Nov; 65(11):1679-1691. PubMed ID: 27456392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.