BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 36221183)

  • 1. Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.
    Tan L; Shan H; Han C; Zhang Z; Shen J; Zhang X; Xiang H; Lu K; Qi C; Li Y; Zhuang G; Chen G; Tan L
    J Med Chem; 2022 Oct; 65(20):13645-13659. PubMed ID: 36221183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ubiquitin-specific protease 8 (USP8/UBPy): a prototypic multidomain deubiquitinating enzyme with pleiotropic functions.
    Dufner A; Knobeloch KP
    Biochem Soc Trans; 2019 Dec; 47(6):1867-1879. PubMed ID: 31845722
    [TBL] [Abstract][Full Text] [Related]  

  • 3. USP8 is a novel target for overcoming gefitinib resistance in lung cancer.
    Byun S; Lee SY; Lee J; Jeong CH; Farrand L; Lim S; Reddy K; Kim JY; Lee MH; Lee HJ; Bode AM; Won Lee K; Dong Z
    Clin Cancer Res; 2013 Jul; 19(14):3894-904. PubMed ID: 23748694
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
    Gao W; Rui Y; Li G; Zhai C; Su J; Liu H; Zheng W; Zheng B; Zhang W; Yang Y; Hua S; Yu X
    Front Immunol; 2021; 12():740713. PubMed ID: 34630422
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome.
    Berlin I; Higginbotham KM; Dise RS; Sierra MI; Nash PD
    J Biol Chem; 2010 Nov; 285(48):37895-908. PubMed ID: 20876529
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deubiquitinase USP8 increases ID1 stability and promotes esophageal squamous cell carcinoma tumorigenesis.
    Li L; Liu Y; Zhao Y; Feng R; Li Y; Yu X; Liu Z; Wang L
    Cancer Lett; 2022 Aug; 542():215760. PubMed ID: 35636624
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma.
    McHugh A; Fernandes K; Chinner N; Ibrahim AFM; Garg AK; Boag G; Hepburn LA; Proby CM; Leigh IM; Saville MK
    J Invest Dermatol; 2020 Jun; 140(6):1154-1165.e5. PubMed ID: 31705877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.
    Yeates EF; Tesco G
    J Biol Chem; 2016 Jul; 291(30):15753-66. PubMed ID: 27302062
    [TBL] [Abstract][Full Text] [Related]  

  • 9. USP8 inhibition regulates autophagy flux and controls
    Santelices J; Ou M; Maegawa GHB; Hercik K; Edelmann MJ
    Front Cell Infect Microbiol; 2023; 13():1070271. PubMed ID: 37026055
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
    Sun J; Hu Q; Peng H; Peng C; Zhou L; Lu J; Huang C
    J Biol Chem; 2018 May; 293(21):8275-8284. PubMed ID: 29626091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitin-specific protease 8 links the PTEN-Akt-AIP4 pathway to the control of FLIPS stability and TRAIL sensitivity in glioblastoma multiforme.
    Panner A; Crane CA; Weng C; Feletti A; Fang S; Parsa AT; Pieper RO
    Cancer Res; 2010 Jun; 70(12):5046-53. PubMed ID: 20484045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening.
    Han J; Tian Y; Yu L; Zhang Q; Xu X; Zhang Y; Wang J; Ma Z; Bian J; Luo C; Jiang H; Chen K; Zhao Y; Li Z; Ding H
    Bioorg Chem; 2020 Aug; 101():103962. PubMed ID: 32480171
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The deubiquitinase OTUB1 governs lung cancer cell fitness by modulating proteostasis of OXPHOS proteins.
    Sheryazdanova A; Amoedo ND; Dufour S; Impens F; Rossignol R; Sablina A
    Biochim Biophys Acta Mol Basis Dis; 2023 Oct; 1869(7):166767. PubMed ID: 37245529
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The oncogenic role of ubiquitin specific peptidase (USP8) and its signaling pathways targeting for cancer therapeutics.
    Islam MT; Chen F; Chen H
    Arch Biochem Biophys; 2021 Apr; 701():108811. PubMed ID: 33600786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.
    Kakihara K; Asamizu K; Moritsugu K; Kubo M; Kitaguchi T; Endo A; Kidera A; Ikeguchi M; Kato A; Komada M; Fukushima T
    Commun Biol; 2021 Nov; 4(1):1272. PubMed ID: 34750505
    [TBL] [Abstract][Full Text] [Related]  

  • 16. USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin.
    Durcan TM; Tang MY; Pérusse JR; Dashti EA; Aguileta MA; McLelland GL; Gros P; Shaler TA; Faubert D; Coulombe B; Fon EA
    EMBO J; 2014 Nov; 33(21):2473-91. PubMed ID: 25216678
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.
    Kim Y; Shiba-Ishii A; Nakagawa T; Husni RE; Sakashita S; Takeuchi T; Noguchi M
    Pathol Int; 2017 Jun; 67(6):292-301. PubMed ID: 28544031
    [TBL] [Abstract][Full Text] [Related]  

  • 18. USP8 modulates ubiquitination of LRIG1 for Met degradation.
    Oh YM; Lee SB; Choi J; Suh HY; Shim S; Song YJ; Kim B; Lee JM; Oh SJ; Jeong Y; Cheong KH; Song PH; Kim KA
    Sci Rep; 2014 May; 4():4980. PubMed ID: 24828152
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
    Peng H; Yang F; Hu Q; Sun J; Peng C; Zhao Y; Huang C
    Autophagy; 2020 Apr; 16(4):698-708. PubMed ID: 31241013
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reciprocal cross-regulation between RNF41 and USP8 controls cytokine receptor sorting and processing.
    De Ceuninck L; Wauman J; Masschaele D; Peelman F; Tavernier J
    J Cell Sci; 2013 Aug; 126(Pt 16):3770-81. PubMed ID: 23750007
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.