BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 36222238)

  • 1. Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle.
    Coakley-Youngs E; Ranatunga M; Richardson S; Getti G; Shorter S; Fivaz M
    Biol Open; 2022 Sep; 11(9):. PubMed ID: 36222238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.
    Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM
    Mol Autism; 2017; 8():11. PubMed ID: 28321286
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.
    Shi X; Lu C; Corman A; Nikish A; Zhou Y; Platt RJ; Iossifov I; Zhang F; Pan JQ; Sanjana NE
    Am J Hum Genet; 2023 Oct; 110(10):1750-1768. PubMed ID: 37802044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.
    Sugathan A; Biagioli M; Golzio C; Erdin S; Blumenthal I; Manavalan P; Ragavendran A; Brand H; Lucente D; Miles J; Sheridan SD; Stortchevoi A; Kellis M; Haggarty SJ; Katsanis N; Gusella JF; Talkowski ME
    Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4468-77. PubMed ID: 25294932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons.
    Kawamura A; Nishiyama M
    Commun Biol; 2023 Jun; 6(1):593. PubMed ID: 37268684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development.
    Hurley S; Mohan C; Suetterlin P; Ellingford R; Riegman KLH; Ellegood J; Caruso A; Michetti C; Brock O; Evans R; Rudari F; Delogu A; Scattoni ML; Lerch JP; Fernandes C; Basson MA
    Mol Autism; 2021 Feb; 12(1):16. PubMed ID: 33627187
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes.
    Wilkinson B; Grepo N; Thompson BL; Kim J; Wang K; Evgrafov OV; Lu W; Knowles JA; Campbell DB
    Transl Psychiatry; 2015 May; 5(5):e568. PubMed ID: 25989142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment.
    Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP
    Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories.
    Villa CE; Cheroni C; Dotter CP; López-Tóbon A; Oliveira B; Sacco R; Yahya AÇ; Morandell J; Gabriele M; Tavakoli MR; Lyudchik J; Sommer C; Gabitto M; Danzl JG; Testa G; Novarino G
    Cell Rep; 2022 Apr; 39(1):110615. PubMed ID: 35385734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1.
    Haddad Derafshi B; Danko T; Chanda S; Batista PJ; Litzenburger U; Lee QY; Ng YH; Sebin A; Chang HY; Südhof TC; Wernig M
    Sci Rep; 2022 Dec; 12(1):22425. PubMed ID: 36575212
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The autism-associated protein CHD8 is required for cerebellar development and motor function.
    Kawamura A; Katayama Y; Kakegawa W; Ino D; Nishiyama M; Yuzaki M; Nakayama KI
    Cell Rep; 2021 Apr; 35(1):108932. PubMed ID: 33826902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling.
    Durak O; Gao F; Kaeser-Woo YJ; Rueda R; Martorell AJ; Nott A; Liu CY; Watson LA; Tsai LH
    Nat Neurosci; 2016 Nov; 19(11):1477-1488. PubMed ID: 27694995
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation.
    Sood S; Weber CM; Hodges HC; Krokhotin A; Shalizi A; Crabtree GR
    Proc Natl Acad Sci U S A; 2020 Sep; 117(36):22331-22340. PubMed ID: 32839322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conserved and Distinct Functions of the Autism-Related Chromatin Remodeler CHD8 in Embryonic and Adult Forebrain Neurogenesis.
    Dong C; Zhao C; Chen X; Berry K; Wang J; Zhang F; Liao Y; Han R; Ogurek S; Xu L; Zhang L; Lin Y; Zhou W; Xin M; Lim DA; Campbell K; Nakafuku M; Waclaw RR; Lu QR
    J Neurosci; 2022 Nov; 42(44):8373-8392. PubMed ID: 36127134
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CHD8 haploinsufficiency results in autistic-like phenotypes in mice.
    Katayama Y; Nishiyama M; Shoji H; Ohkawa Y; Kawamura A; Sato T; Suyama M; Takumi T; Miyakawa T; Nakayama KI
    Nature; 2016 Sep; 537(7622):675-679. PubMed ID: 27602517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants.
    Siu MT; Butcher DT; Turinsky AL; Cytrynbaum C; Stavropoulos DJ; Walker S; Caluseriu O; Carter M; Lou Y; Nicolson R; Georgiades S; Szatmari P; Anagnostou E; Scherer SW; Choufani S; Brudno M; Weksberg R
    Clin Epigenetics; 2019 Jul; 11(1):103. PubMed ID: 31311581
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
    Modafferi S; Zhong X; Kleensang A; Murata Y; Fagiani F; Pamies D; Hogberg HT; Calabrese V; Lachman H; Hartung T; Smirnova L
    Environ Health Perspect; 2021 Jul; 129(7):77001. PubMed ID: 34259569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single-Cell Transcriptomics Supports a Role of
    Hoffmann A; Spengler D
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33806835
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CHD8 intragenic deletion associated with autism spectrum disorder.
    Stolerman ES; Smith B; Chaubey A; Jones JR
    Eur J Med Genet; 2016 Apr; 59(4):189-94. PubMed ID: 26921529
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism.
    Cherepanov SM; Gerasimenko M; Yuhi T; Furuhara K; Tsuji C; Yokoyama S; Nakayama KI; Nishiyama M; Higashida H
    BMC Neurosci; 2021 May; 22(1):32. PubMed ID: 33933000
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.