275 related articles for article (PubMed ID: 36227868)
1. The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration.
Wang Y; Ma X; Muthuraman P; Raja A; Jayaraman A; Petrukhin K; Cioffi CL; Ma JX; Moiseyev G
PLoS One; 2022; 17(10):e0269437. PubMed ID: 36227868
[TBL] [Abstract][Full Text] [Related]
2. Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity.
Bavik C; Henry SH; Zhang Y; Mitts K; McGinn T; Budzynski E; Pashko A; Lieu KL; Zhong S; Blumberg B; Kuksa V; Orme M; Scott I; Fawzi A; Kubota R
PLoS One; 2015; 10(5):e0124940. PubMed ID: 25970164
[TBL] [Abstract][Full Text] [Related]
3. A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration.
Shin Y; Moiseyev G; Petrukhin K; Cioffi CL; Muthuraman P; Takahashi Y; Ma JX
Biochim Biophys Acta Mol Basis Dis; 2018 Jul; 1864(7):2420-2429. PubMed ID: 29684583
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease.
Moiseyev G; Nikolaeva O; Chen Y; Farjo K; Takahashi Y; Ma JX
Proc Natl Acad Sci U S A; 2010 Oct; 107(41):17551-6. PubMed ID: 20876139
[TBL] [Abstract][Full Text] [Related]
5. Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.
Lenis TL; Sarfare S; Jiang Z; Lloyd MB; Bok D; Radu RA
Proc Natl Acad Sci U S A; 2017 Apr; 114(15):3987-3992. PubMed ID: 28348233
[TBL] [Abstract][Full Text] [Related]
6. Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.
Boyer NP; Higbee D; Currin MB; Blakeley LR; Chen C; Ablonczy Z; Crouch RK; Koutalos Y
J Biol Chem; 2012 Jun; 287(26):22276-86. PubMed ID: 22570475
[TBL] [Abstract][Full Text] [Related]
7. Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments.
Li S; Sato K; Gordon WC; Sendtner M; Bazan NG; Jin M
J Biol Chem; 2018 Sep; 293(39):15256-15268. PubMed ID: 30115683
[TBL] [Abstract][Full Text] [Related]
8. Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration.
Radu RA; Mata NL; Nusinowitz S; Liu X; Sieving PA; Travis GH
Proc Natl Acad Sci U S A; 2003 Apr; 100(8):4742-7. PubMed ID: 12671074
[TBL] [Abstract][Full Text] [Related]
9. The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.
Kim SR; Jang YP; Jockusch S; Fishkin NE; Turro NJ; Sparrow JR
Proc Natl Acad Sci U S A; 2007 Dec; 104(49):19273-8. PubMed ID: 18048333
[TBL] [Abstract][Full Text] [Related]
10. A vicious cycle of bisretinoid formation and oxidation relevant to recessive Stargardt disease.
Zhao J; Kim HJ; Ueda K; Zhang K; Montenegro D; Dunaief JL; Sparrow JR
J Biol Chem; 2021; 296():100259. PubMed ID: 33837742
[TBL] [Abstract][Full Text] [Related]
11. Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration.
Mata NL; Weng J; Travis GH
Proc Natl Acad Sci U S A; 2000 Jun; 97(13):7154-9. PubMed ID: 10852960
[TBL] [Abstract][Full Text] [Related]
12. Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium.
Boyer NP; Thompson DA; Koutalos Y
Invest Ophthalmol Vis Sci; 2021 Feb; 62(2):1. PubMed ID: 33523199
[TBL] [Abstract][Full Text] [Related]
13. Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.
Li S; Lee J; Zhou Y; Gordon WC; Hill JM; Bazan NG; Miner JH; Jin M
J Neurosci; 2013 Feb; 33(7):3178-89. PubMed ID: 23407971
[TBL] [Abstract][Full Text] [Related]
14. Light damage in Abca4 and Rpe65rd12 mice.
Wu L; Ueda K; Nagasaki T; Sparrow JR
Invest Ophthalmol Vis Sci; 2014 Mar; 55(3):1910-8. PubMed ID: 24576873
[TBL] [Abstract][Full Text] [Related]
15. Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.
Conley SM; Cai X; Makkia R; Wu Y; Sparrow JR; Naash MI
Biochim Biophys Acta; 2012 Jul; 1822(7):1169-79. PubMed ID: 22033104
[TBL] [Abstract][Full Text] [Related]
16. Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
Zhang J; Kiser PD; Badiee M; Palczewska G; Dong Z; Golczak M; Tochtrop GP; Palczewski K
J Clin Invest; 2015 Jul; 125(7):2781-94. PubMed ID: 26075817
[TBL] [Abstract][Full Text] [Related]
17. Retinopathy in mice induced by disrupted all-trans-retinal clearance.
Maeda A; Maeda T; Golczak M; Palczewski K
J Biol Chem; 2008 Sep; 283(39):26684-93. PubMed ID: 18658157
[TBL] [Abstract][Full Text] [Related]
18. Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.
Wu Y; Fishkin NE; Pande A; Pande J; Sparrow JR
J Biol Chem; 2009 Jul; 284(30):20155-66. PubMed ID: 19478335
[TBL] [Abstract][Full Text] [Related]
19. Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease.
Fontaine V; Monteiro E; Fournié M; Brazhnikova E; Boumedine T; Vidal C; Balducci C; Guibout L; Latil M; Dilda PJ; Veillet S; Sahel JA; Lafont R; Camelo S
Aging (Albany NY); 2020 Apr; 12(7):6151-6171. PubMed ID: 32255762
[TBL] [Abstract][Full Text] [Related]
20. Protective Effect of a Locked Retinal Chromophore Analog against Light-Induced Retinal Degeneration.
Gao S; Parmar T; Palczewska G; Dong Z; Golczak M; Palczewski K; Jastrzebska B
Mol Pharmacol; 2018 Oct; 94(4):1132-1144. PubMed ID: 30018116
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]