BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 36234741)

  • 41. Cytotoxicity and apoptosis of benzoquinones: redox cycling, cytochrome c release, and BAD protein expression.
    Tudor G; Gutierrez P; Aguilera-Gutierrez A; Sausville EA
    Biochem Pharmacol; 2003 Apr; 65(7):1061-75. PubMed ID: 12663042
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential.
    Colucci MA; Moody CJ; Couch GD
    Org Biomol Chem; 2008 Feb; 6(4):637-56. PubMed ID: 18264564
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Concurrent Reactive Oxygen Species Generation and Aneuploidy Induction Contribute to Thymoquinone Anticancer Activity.
    Al-Hayali M; Garces A; Stocks M; Collins H; Bradshaw TD
    Molecules; 2021 Aug; 26(17):. PubMed ID: 34500570
    [TBL] [Abstract][Full Text] [Related]  

  • 44. DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90.
    Kelland LR; Sharp SY; Rogers PM; Myers TG; Workman P
    J Natl Cancer Inst; 1999 Nov; 91(22):1940-9. PubMed ID: 10564678
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Synthesis and evaluation of (±)-dunnione and its ortho-quinone analogues as substrates for NAD(P)H:quinone oxidoreductase 1 (NQO1).
    Bian J; Xu L; Deng B; Qian X; Fan J; Yang X; Liu F; Xu X; Guo X; Li X; Sun H; You Q; Zhang X
    Bioorg Med Chem Lett; 2015 Mar; 25(6):1244-8. PubMed ID: 25677663
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer.
    Wu X; Li X; Li Z; Yu Y; You Q; Zhang X
    J Med Chem; 2018 Dec; 61(24):11280-11297. PubMed ID: 30508483
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synthesis and biological evaluation of novel isothiazoloquinoline quinone analogues.
    Chen L; Xie YZ; Luo ZY; Liu LJ; Zou ZZ; Liu HD; Kong FR; Hao Y; Gao JL; Wang LL; Ma DY; Liu SY
    Bioorg Med Chem Lett; 2020 Aug; 30(16):127286. PubMed ID: 32631508
    [TBL] [Abstract][Full Text] [Related]  

  • 48. NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase.
    Joseph P; Jaiswal AK
    Proc Natl Acad Sci U S A; 1994 Aug; 91(18):8413-7. PubMed ID: 8078896
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Indolequinone antitumor agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase. Part 2.
    Swann E; Barraja P; Oberlander AM; Gardipee WT; Hudnott AR; Beall HD; Moody CJ
    J Med Chem; 2001 Sep; 44(20):3311-9. PubMed ID: 11563930
    [TBL] [Abstract][Full Text] [Related]  

  • 50. NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors.
    Han Y; Shen H; Carr BI; Wipf P; Lazo JS; Pan SS
    J Pharmacol Exp Ther; 2004 Apr; 309(1):64-70. PubMed ID: 14718602
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Synthesis of new antiproliferative 1,3,4-substituted-pyrrolo[3,2-c]quinoline derivatives, biological and in silico insights.
    Mingoia F; Di Sano C; D'Anna C; Fazzari M; Minafra L; Bono A; La Monica G; Martorana A; Almerico AM; Lauria A
    Eur J Med Chem; 2023 Oct; 258():115537. PubMed ID: 37329715
    [TBL] [Abstract][Full Text] [Related]  

  • 52. An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancer.
    Liu F; Yu G; Wang G; Liu H; Wu X; Wang Q; Liu M; Liao K; Wu M; Cheng X; Hao H
    PLoS One; 2012; 7(7):e42138. PubMed ID: 22848731
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Hybrids of 1,4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study.
    Kadela-Tomanek M; Krzykawski K; Halama A; Kubina R
    Molecules; 2023 Sep; 28(18):. PubMed ID: 37764419
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress.
    Nemeikaite-Ceniene A; Sarlauskas J; Anusevicius Z; Nivinskas H; Cenas N
    Arch Biochem Biophys; 2003 Aug; 416(1):110-8. PubMed ID: 12859987
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Role of NADPH cytochrome P450 reductase in activation of RH1.
    Begleiter A; Leith MK; Patel D; Hasinoff BB
    Cancer Chemother Pharmacol; 2007 Oct; 60(5):713-23. PubMed ID: 17256129
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Influence of DT diaphorase on quinone-mediated genotoxicity in human and fish cell lines.
    Hasspieler BM; Haffner GD; Adeli K
    Mutat Res; 1996 May; 360(1):43-9. PubMed ID: 8657209
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A; Leith MK; Curphey TJ; Doherty GP
    Oncol Res; 1997; 9(6-7):371-82. PubMed ID: 9406243
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) and genomic gain of the NQO1 locus modulates breast cancer cell sensitivity to quinones.
    Glorieux C; Sandoval JM; Dejeans N; Ameye G; Poirel HA; Verrax J; Calderon PB
    Life Sci; 2016 Jan; 145():57-65. PubMed ID: 26687450
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Anticancer activity of newly synthesized 1,1-disubstituted cyclohexane-1-carboxamides: in vitro caspases mediated apoptosis activators in human cancer cell lines and their molecular modeling.
    Abd-Allah WH; Salman A; Sabry Saad S
    Drug Dev Res; 2019 Nov; 80(7):933-947. PubMed ID: 31343754
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Synthesis of new quinolinequinone derivatives and preliminary exploration of their cytotoxic properties.
    Keyari CM; Kearns AK; Duncan NS; Eickholt EA; Abbott G; Beall HD; Diaz P
    J Med Chem; 2013 May; 56(10):3806-19. PubMed ID: 23574193
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.