These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 36234948)

  • 21. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.
    Hassler MR; Turanov AA; Alterman JF; Haraszti RA; Coles AH; Osborn MF; Echeverria D; Nikan M; Salomon WE; Roux L; Godinho BMDC; Davis SM; Morrissey DV; Zamore PD; Karumanchi SA; Moore MJ; Aronin N; Khvorova A
    Nucleic Acids Res; 2018 Mar; 46(5):2185-2196. PubMed ID: 29432571
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The effects of thiophosphate substitutions on native siRNA gene silencing.
    Li ZY; Mao H; Kallick DA; Gorenstein DG
    Biochem Biophys Res Commun; 2005 Apr; 329(3):1026-30. PubMed ID: 15752758
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, gene silencing, and molecular modeling studies of 4'-C-aminomethyl-2'-O-methyl modified small interfering RNAs.
    Gore KR; Nawale GN; Harikrishna S; Chittoor VG; Pandey SK; Höbartner C; Patankar S; Pradeepkumar PI
    J Org Chem; 2012 Apr; 77(7):3233-45. PubMed ID: 22372696
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The potency of siRNA-mediated growth inhibition following silencing of essential genes is dependent on siRNA design and varies with target sequence.
    Patel R; T'wallant NC; Herbert MH; White D; Murison JG; Reid G
    Oligonucleotides; 2009 Dec; 19(4):317-28. PubMed ID: 19943803
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Chemically Synthesized, Self-Assembling Small Interfering RNA-Prohead RNA Molecules Trigger Dicer-Independent Gene Silencing.
    Hill AC; van Leeuwen D; Schlösser V; Behera A; Mateescu B; Hall J
    Chemistry; 2022 Feb; 28(8):e202103995. PubMed ID: 34879171
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Precise and efficient siRNA design: a key point in competent gene silencing.
    Fakhr E; Zare F; Teimoori-Toolabi L
    Cancer Gene Ther; 2016 Apr; 23(4):73-82. PubMed ID: 26987292
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing.
    Bartlett DW; Davis ME
    Biotechnol Bioeng; 2007 Jul; 97(4):909-21. PubMed ID: 17154307
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Single-Stranded Silencing RNAs: Hit Rate and Chemical Modification.
    Pendergraff HM; Debacker AJ; Watts JK
    Nucleic Acid Ther; 2016 Aug; 26(4):216-22. PubMed ID: 27123752
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Identification of sequence features that predict competition potency of siRNAs.
    Li X; Yoo JW; Lee JH; Hahn Y; Kim S; Lee DK
    Biochem Biophys Res Commun; 2010 Jul; 398(1):92-7. PubMed ID: 20558136
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Effect of Sugar 2',4'-Modifications on Gene Silencing Activity of siRNA Duplexes.
    Malek-Adamian E; Fakhoury J; Arnold AE; Martínez-Montero S; Shoichet MS; Damha MJ
    Nucleic Acid Ther; 2019 Aug; 29(4):187-194. PubMed ID: 31084536
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The 5' binding MID domain of human Argonaute2 tolerates chemically modified nucleotide analogues.
    Deleavey GF; Frank F; Hassler M; Wisnovsky S; Nagar B; Damha MJ
    Nucleic Acid Ther; 2013 Feb; 23(1):81-7. PubMed ID: 23289589
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The valency of fatty acid conjugates impacts siRNA pharmacokinetics, distribution, and efficacy in vivo.
    Biscans A; Coles A; Echeverria D; Khvorova A
    J Control Release; 2019 May; 302():116-125. PubMed ID: 30940496
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Designing an effective therapeutic siRNA to silence RdRp gene of SARS-CoV-2.
    Shawan MMAK; Sharma AR; Bhattacharya M; Mallik B; Akhter F; Shakil MS; Hossain MM; Banik S; Lee SS; Hasan MA; Chakraborty C
    Infect Genet Evol; 2021 Sep; 93():104951. PubMed ID: 34089909
    [TBL] [Abstract][Full Text] [Related]  

  • 34. 5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo.
    Haraszti RA; Roux L; Coles AH; Turanov AA; Alterman JF; Echeverria D; Godinho BMDC; Aronin N; Khvorova A
    Nucleic Acids Res; 2017 Jul; 45(13):7581-7592. PubMed ID: 28591791
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Building siRNAs with Cubes: Synthesis and Evaluation of Cubane-Modified siRNAs.
    Hammill ML; Salim L; Tsubaki K; Varley AJ; Kitamura M; Okauchi T; Desaulniers JP
    Chembiochem; 2021 Oct; 22(20):2981-2985. PubMed ID: 34319643
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Chemical and structural diversity of siRNA molecules.
    Nawrot B; Sipa K
    Curr Top Med Chem; 2006; 6(9):913-25. PubMed ID: 16787284
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Effective carrier-free gene-silencing activity of sphingosine-modified siRNAs.
    Fernandez C; Giorgees I; Goss E; Desaulniers JP
    Org Biomol Chem; 2023 Mar; 21(10):2107-2117. PubMed ID: 36645381
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Computational models with thermodynamic and composition features improve siRNA design.
    Shabalina SA; Spiridonov AN; Ogurtsov AY
    BMC Bioinformatics; 2006 Feb; 7():65. PubMed ID: 16472402
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing.
    Harborth J; Elbashir SM; Vandenburgh K; Manninga H; Scaringe SA; Weber K; Tuschl T
    Antisense Nucleic Acid Drug Dev; 2003 Apr; 13(2):83-105. PubMed ID: 12804036
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Gene-silencing potency of symmetric and asymmetric lipid-conjugated siRNAs and its correlation with dicer recognition.
    Kubo T; Yanagihara K; Sato Y; Nishimura Y; Kondo S; Seyama T
    Bioconjug Chem; 2013 Dec; 24(12):2045-57. PubMed ID: 24274056
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.