BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 36235254)

  • 1. AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model.
    Goswami A; Deb B; Goyal S; Gosavi A; Mali M; Martis AM; Khurana P; Gangar M; Raykar D; Mohanty A; Kulkarni A
    Molecules; 2022 Oct; 27(19):. PubMed ID: 36235254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of Novel Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Tumor Immunotherapy.
    Wang X; Lu X; Yan D; Zhou Y; Tan X
    Int J Mol Sci; 2022 Jun; 23(13):. PubMed ID: 35806118
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor Exosomal ENPP1 Hydrolyzes cGAMP to Inhibit cGAS-STING Signaling.
    An Y; Zhu J; Xie Q; Feng J; Gong Y; Fan Q; Cao J; Huang Z; Shi W; Lin Q; Wu L; Yang C; Ji T
    Adv Sci (Weinh); 2024 May; 11(20):e2308131. PubMed ID: 38498770
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of Pyrido[2,3-
    Sun Y; Chen M; Han Y; Li W; Ma X; Shi Z; Zhou Y; Xu L; Yu L; Wang Y; Yu J; Diao X; Meng L; Xu S
    J Med Chem; 2024 Mar; 67(5):3986-4006. PubMed ID: 38387074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer.
    Wang S; Böhnert V; Joseph AJ; Sudaryo V; Skariah G; Swinderman JT; Yu FB; Subramanyam V; Wolf DM; Lyu X; Gilbert LA; Van't Veer LJ; Goodarzi H; Li L
    Proc Natl Acad Sci U S A; 2023 Dec; 120(52):e2313693120. PubMed ID: 38117852
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
    Kato K; Nishimasu H; Oikawa D; Hirano S; Hirano H; Kasuya G; Ishitani R; Tokunaga F; Nureki O
    Nat Commun; 2018 Oct; 9(1):4424. PubMed ID: 30356045
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1.
    Onyedibe KI; Wang M; Sintim HO
    Molecules; 2019 Nov; 24(22):. PubMed ID: 31752288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy.
    Cho Y; Kang M; Ji SH; Jeong HJ; Jung JE; Oh DH; Park S; Park YY; Choi J; Kim S; Kim NJ; Lee DH; Park CS; Han SJ; Lee S; Choi J
    J Med Chem; 2023 Nov; 66(22):15141-15170. PubMed ID: 37963811
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects.
    Guan D; Fang L; Feng M; Guo S; Xie L; Chen C; Sun X; Wu Q; Yuan X; Xie Z; Zhou J; Zhang H
    Eur J Med Chem; 2024 Mar; 267():116211. PubMed ID: 38359537
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP.
    Carozza JA; Brown JA; Böhnert V; Fernandez D; AlSaif Y; Mardjuki RE; Smith M; Li L
    Cell Chem Biol; 2020 Nov; 27(11):1347-1358.e5. PubMed ID: 32726585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel pyrrolopyrimidine and pyrrolopyridine derivatives as potent ENPP1 inhibitors.
    Jeong HJ; Lee HL; Kim SJ; Jeong JH; Ji SH; Kim HB; Kang M; Chung HW; Park CS; Choo H; Yoon HJ; Kim NJ; Lee DH; Lee SH; Han SJ
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):2434-2451. PubMed ID: 36069240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells.
    Vasiyani H; Shinde A; Roy M; Mane M; Singh K; Singh J; Gohel D; Currim F; Vaidya K; Chhabria M; Singh R
    Apoptosis; 2021 Jun; 26(5-6):293-306. PubMed ID: 33840002
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The cyclic guanosine monophosphate synthase-stimulator of interferon genes pathway as a potential target for tumor immunotherapy.
    Chen R; Liu M; Jiang Q; Meng X; Wei J
    Front Immunol; 2023; 14():1121603. PubMed ID: 37153627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.
    Carozza JA; Cordova AF; Brown JA; AlSaif Y; Böhnert V; Cao X; Mardjuki RE; Skariah G; Fernandez D; Li L
    Proc Natl Acad Sci U S A; 2022 May; 119(21):e2119189119. PubMed ID: 35588451
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP.
    Maltbaek JH; Cambier S; Snyder JM; Stetson DB
    Immunity; 2022 Oct; 55(10):1799-1812.e4. PubMed ID: 36070769
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Maintenance of cyclic GMP-AMP homeostasis by ENPP1 is involved in pseudorabies virus infection.
    Wang J; Lu SF; Wan B; Ming SL; Li GL; Su BQ; Liu JY; Wei YS; Yang GY; Chu BB
    Mol Immunol; 2018 Mar; 95():56-63. PubMed ID: 29407577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway.
    Dodantenna N; Ranathunga L; Chathuranga WAG; Weerawardhana A; Cha JW; Subasinghe A; Gamage N; Haluwana DK; Kim Y; Jheong W; Poo H; Lee JS
    J Virol; 2022 Aug; 96(15):e0102222. PubMed ID: 35861515
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint.
    Mardjuki R; Wang S; Carozza J; Zirak B; Subramanyam V; Abhiraman G; Lyu X; Goodarzi H; Li L
    Cell Rep; 2024 May; ():114209. PubMed ID: 38749434
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of cGAMP-Luc, a sensitive and precise coupled enzyme assay to measure cGAMP in complex biological samples.
    Mardjuki RE; Carozza JA; Li L
    J Biol Chem; 2020 Apr; 295(15):4881-4892. PubMed ID: 32127400
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.
    Li L; Yin Q; Kuss P; Maliga Z; Millán JL; Wu H; Mitchison TJ
    Nat Chem Biol; 2014 Dec; 10(12):1043-8. PubMed ID: 25344812
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.