BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 36239424)

  • 1. PIM kinases phosphorylate lactate dehydrogenase A at serine 161 and suppress its nuclear ubiquitination.
    Mung KL; Meinander A; Koskinen PJ
    FEBS J; 2023 May; 290(9):2489-2502. PubMed ID: 36239424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1.
    Mung KL; Eccleshall WB; Santio NM; Rivero-Müller A; Koskinen PJ
    Cell Commun Signal; 2021 Jun; 19(1):68. PubMed ID: 34193159
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
    Ždralević M; Brand A; Di Ianni L; Dettmer K; Reinders J; Singer K; Peter K; Schnell A; Bruss C; Decking SM; Koehl G; Felipe-Abrio B; Durivault J; Bayer P; Evangelista M; O'Brien T; Oefner PJ; Renner K; Pouysségur J; Kreutz M
    J Biol Chem; 2018 Oct; 293(41):15947-15961. PubMed ID: 30158244
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.
    Miyakawa K; Matsunaga S; Yokoyama M; Nomaguchi M; Kimura Y; Nishi M; Kimura H; Sato H; Hirano H; Tamura T; Akari H; Miura T; Adachi A; Sawasaki T; Yamamoto N; Ryo A
    Nat Commun; 2019 Apr; 10(1):1844. PubMed ID: 31015445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.
    Linn DE; Yang X; Xie Y; Alfano A; Deshmukh D; Wang X; Shimelis H; Chen H; Li W; Xu K; Chen M; Qiu Y
    J Biol Chem; 2012 Jun; 287(27):22959-68. PubMed ID: 22584579
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL.
    Macdonald A; Campbell DG; Toth R; McLauchlan H; Hastie CJ; Arthur JS
    BMC Cell Biol; 2006 Jan; 7():1. PubMed ID: 16403219
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial respiration and reactive oxygen species production.
    Newington JT; Rappon T; Albers S; Wong DY; Rylett RJ; Cumming RC
    J Biol Chem; 2012 Oct; 287(44):37245-58. PubMed ID: 22948140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis.
    Zheng J; Dai Y; Lin X; Huang Q; Shi L; Jin X; Liu N; Zhou F; Zhang S
    Mol Med Rep; 2021 Sep; 24(3):. PubMed ID: 34278456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases.
    Zhou M; Crawford Y; Ng D; Tung J; Pynn AF; Meier A; Yuk IH; Vijayasankaran N; Leach K; Joly J; Snedecor B; Shen A
    J Biotechnol; 2011 Apr; 153(1-2):27-34. PubMed ID: 21392546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Palmitoylation alters LDHA activity and pancreatic cancer response to chemotherapy.
    Chen L; Xing X; Zhu Y; Chen Y; Pei H; Song Q; Li J; Zhang P
    Cancer Lett; 2024 Apr; 587():216696. PubMed ID: 38331089
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival.
    Pathria G; Scott DA; Feng Y; Sang Lee J; Fujita Y; Zhang G; Sahu AD; Ruppin E; Herlyn M; Osterman AL; Ronai ZA
    EMBO J; 2018 Oct; 37(20):. PubMed ID: 30209241
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect.
    Woodford MR; Baker-Williams AJ; Sager RA; Backe SJ; Blanden AR; Hashmi F; Kancherla P; Gori A; Loiselle DR; Castelli M; Serapian SA; Colombo G; Haystead TA; Jensen SM; Stetler-Stevenson WG; Loh SN; Schmidt LS; Linehan WM; Bah A; Bourboulia D; Bratslavsky G; Mollapour M
    Nat Struct Mol Biol; 2021 Aug; 28(8):662-670. PubMed ID: 34381247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exploring the possibility of drug repurposing for cancer therapy targeting human lactate dehydrogenase A: a computational approach.
    Paul SK; Dutta Chowdhury K; Dey SR; Paul A; Haldar R
    J Biomol Struct Dyn; 2023 Nov; 41(19):9967-9976. PubMed ID: 36576127
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UCHL3 promotes aerobic glycolysis of pancreatic cancer through upregulating LDHA expression.
    Fan Y; Hu D; Li D; Ma C; Tang Y; Tao Q; Deng L; Tang D
    Clin Transl Oncol; 2021 Aug; 23(8):1637-1645. PubMed ID: 33616859
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exploring the Key Amino Acid Residues Surrounding the Active Center of Lactate Dehydrogenase A for the Development of Ideal Inhibitors.
    Chen J; Chen C; Zhang Z; Zeng F; Zhang S
    Molecules; 2024 Apr; 29(9):. PubMed ID: 38731521
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T-cell acute lymphoblastic leukemia.
    Yu H; Yin Y; Yi Y; Cheng Z; Kuang W; Li R; Zhong H; Cui Y; Yuan L; Gong F; Wang Z; Li H; Peng H; Zhang G
    Cancer Commun (Lond); 2020 Oct; 40(10):501-517. PubMed ID: 32820611
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pim family kinases enhance tumor growth of prostate cancer cells.
    Chen WW; Chan DC; Donald C; Lilly MB; Kraft AS
    Mol Cancer Res; 2005 Aug; 3(8):443-51. PubMed ID: 16123140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. miR-489 suppresses multiple myeloma cells growth through inhibition of LDHA-mediated aerobic glycolysis.
    Wu H; Wang X; Wu T; Yang S
    Genes Genomics; 2020 Mar; 42(3):291-297. PubMed ID: 31872383
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fbw7 Inhibits the Progression of Activated B-Cell Like Diffuse Large B-Cell Lymphoma by Targeting the Positive Feedback Loop of the LDHA/lactate/miR-223 Axis.
    Yao S; Guo T; Zhang F; Chen Y; Xu F; Luo D; Luo X; Lin D; Chen W; Li Z; Liu Y
    Front Oncol; 2022; 12():842356. PubMed ID: 35359405
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel Peptide Inhibitors for Lactate Dehydrogenase A (LDHA): A Survey to Inhibit LDHA Activity via Disruption of Protein-Protein Interaction.
    Jafary F; Ganjalikhany MR; Moradi A; Hemati M; Jafari S
    Sci Rep; 2019 Mar; 9(1):4686. PubMed ID: 30886157
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.