BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 36240066)

  • 1. Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.
    Hunter JE; Campbell AE; Hannaway NL; Kerridge S; Luli S; Butterworth JA; Sellier H; Mukherjee R; Dhillon N; Sudhindar PD; Shukla R; Brownridge PJ; Bell HL; Coxhead J; Taylor L; Leary P; Hasoon MSR; Collins I; Garrett MD; Eyers CE; Perkins ND
    Biochem J; 2022 Oct; 479(19):2063-2086. PubMed ID: 36240066
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells.
    Hunter JE; Campbell AE; Kerridge S; Fraser C; Hannaway NL; Luli S; Ivanova I; Brownridge PJ; Coxhead J; Taylor L; Leary P; Hasoon MSR; Eyers CE; Perkins ND
    Biochem J; 2022 Oct; 479(19):2131-2151. PubMed ID: 36240067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma.
    Hunter JE; Butterworth JA; Zhao B; Sellier H; Campbell KJ; Thomas HD; Bacon CM; Cockell SJ; Gewurz BE; Perkins ND
    Oncogene; 2016 Jun; 35(26):3476-84. PubMed ID: 26522720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Myc suppression of Nfkb2 accelerates lymphomagenesis.
    Keller U; Huber J; Nilsson JA; Fallahi M; Hall MA; Peschel C; Cleveland JL
    BMC Cancer; 2010 Jul; 10():348. PubMed ID: 20598117
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells.
    Mensink M; Anstee NS; Robati M; Schenk RL; Herold MJ; Cory S; Vandenberg CJ
    Cell Death Differ; 2018 Mar; 25(4):797-808. PubMed ID: 29339775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Therapeutic implications for the induced levels of Chk1 in Myc-expressing cancer cells.
    Höglund A; Nilsson LM; Muralidharan SV; Hasvold LA; Merta P; Rudelius M; Nikolova V; Keller U; Nilsson JA
    Clin Cancer Res; 2011 Nov; 17(22):7067-79. PubMed ID: 21933891
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphoma.
    Walton MI; Eve PD; Hayes A; Henley AT; Valenti MR; De Haven Brandon AK; Box G; Boxall KJ; Tall M; Swales K; Matthews TP; McHardy T; Lainchbury M; Osborne J; Hunter JE; Perkins ND; Aherne GW; Reader JC; Raynaud FI; Eccles SA; Collins I; Garrett MD
    Oncotarget; 2016 Jan; 7(3):2329-42. PubMed ID: 26295308
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Caspase-resistant ROCK1 expression prolongs survival of Eµ-Myc B cell lymphoma mice.
    Mardilovich K; Naylor G; Julian L; Phinichkusolchit N; Keeshan K; Blyth K; Olson MF
    Dis Model Mech; 2024 May; 17(5):. PubMed ID: 38616733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs.
    Walton MI; Eve PD; Hayes A; Valenti MR; De Haven Brandon AK; Box G; Hallsworth A; Smith EL; Boxall KJ; Lainchbury M; Matthews TP; Jamin Y; Robinson SP; Aherne GW; Reader JC; Chesler L; Raynaud FI; Eccles SA; Collins I; Garrett MD
    Clin Cancer Res; 2012 Oct; 18(20):5650-61. PubMed ID: 22929806
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Addiction to Runx1 is partially attenuated by loss of p53 in the Eµ-Myc lymphoma model.
    Borland G; Kilbey A; Hay J; Gilroy K; Terry A; Mackay N; Bell M; McDonald A; Mills K; Cameron E; Neil JC
    Oncotarget; 2016 Apr; 7(17):22973-87. PubMed ID: 27056890
    [TBL] [Abstract][Full Text] [Related]  

  • 11. B lymphocytes promote lymphogenous metastasis of lymphoma and melanoma.
    Ruddell A; Harrell MI; Furuya M; Kirschbaum SB; Iritani BM
    Neoplasia; 2011 Aug; 13(8):748-57. PubMed ID: 21847366
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis.
    Potts MA; Mizutani S; Garnham AL; Li Wai Suen CSN; Kueh AJ; Tai L; Pal M; Strasser A; Herold MJ
    Cell Death Differ; 2023 Jun; 30(6):1447-1456. PubMed ID: 36894688
    [TBL] [Abstract][Full Text] [Related]  

  • 13. c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells.
    David A; Arnaud N; Fradet M; Lascaux H; Ouk-Martin C; Gachard N; Zimber-Strobl U; Feuillard J; Faumont N
    Haematologica; 2017 May; 102(5):883-894. PubMed ID: 28232371
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma.
    Ravi D; Beheshti A; Abermil N; Passero F; Sharma J; Coyle M; Kritharis A; Kandela I; Hlatky L; Sitkovsky MV; Mazar A; Gartenhaus RB; Evens AM
    Cancer Res; 2016 Jun; 76(11):3319-31. PubMed ID: 26988986
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple DNA damage-dependent and DNA damage-independent stress responses define the outcome of ATR/Chk1 targeting in medulloblastoma cells.
    Krüger K; Geist K; Stuhldreier F; Schumacher L; Blümel L; Remke M; Wesselborg S; Stork B; Klöcker N; Bormann S; Roos WP; Honnen S; Fritz G
    Cancer Lett; 2018 Aug; 430():34-46. PubMed ID: 29753759
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alternative and canonical NF-kB pathways DNA-binding hierarchies networks define Hodgkin lymphoma and Non-Hodgkin diffuse large B Cell lymphoma respectively.
    Gamboa-Cedeño AM; Castillo M; Xiao W; Waldmann TA; Ranuncolo SM
    J Cancer Res Clin Oncol; 2019 Jun; 145(6):1437-1448. PubMed ID: 30941572
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The IKK2/NF-{kappa}B pathway suppresses MYC-induced lymphomagenesis.
    Klapproth K; Sander S; Marinkovic D; Baumann B; Wirth T
    Blood; 2009 Sep; 114(12):2448-58. PubMed ID: 19628709
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EBV latent membrane protein 2A orchestrates p27
    Fish K; Sora RP; Schaller SJ; Longnecker R; Ikeda M
    Blood; 2017 Dec; 130(23):2516-2526. PubMed ID: 29074502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Eµ-hnRNP K Murine Model of Lymphoma: Novel Insights into the Role of hnRNP K in B-Cell Malignancies.
    Malaney P; Velasco-Estevez M; Aguilar-Garrido P; Aitken MJL; Chan LE; Zhang X; Post SM; Gallardo M
    Front Immunol; 2021; 12():634584. PubMed ID: 33912162
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maintenance of nuclear factor-kappa B/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of I kappa B proteins.
    Schauer SL; Wang Z; Sonenshein GE; Rothstein TL
    J Immunol; 1996 Jul; 157(1):81-6. PubMed ID: 8683159
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.