163 related articles for article (PubMed ID: 36242092)
1. PARP1-MGMT complex underpins pathway crosstalk in O
Cropper JD; Alimbetov DS; Brown KTG; Likhotvorik RI; Robles AJ; Guerra JT; He B; Chen Y; Kwon Y; Kurmasheva RT
J Hematol Oncol; 2022 Oct; 15(1):146. PubMed ID: 36242092
[TBL] [Abstract][Full Text] [Related]
2. PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma.
Wu S; Li X; Gao F; de Groot JF; Koul D; Yung WKA
Neuro Oncol; 2021 Jun; 23(6):920-931. PubMed ID: 33433610
[TBL] [Abstract][Full Text] [Related]
3. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
Kaina B; Christmann M; Naumann S; Roos WP
DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
[TBL] [Abstract][Full Text] [Related]
4. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
[TBL] [Abstract][Full Text] [Related]
5. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O
Kraus A; McKeague M; Seiwert N; Nagel G; Geisen SM; Ziegler N; Trantakis IA; Kaina B; Thomas AD; Sturla SJ; Fahrer J
Arch Toxicol; 2019 Feb; 93(2):559-572. PubMed ID: 30446773
[TBL] [Abstract][Full Text] [Related]
6. Temozolomide: mechanisms of action, repair and resistance.
Zhang J; Stevens MF; Bradshaw TD
Curr Mol Pharmacol; 2012 Jan; 5(1):102-14. PubMed ID: 22122467
[TBL] [Abstract][Full Text] [Related]
7. Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
Göder A; Nagel G; Kraus A; Dörsam B; Seiwert N; Kaina B; Fahrer J
Carcinogenesis; 2015 Aug; 36(8):817-31. PubMed ID: 25998848
[TBL] [Abstract][Full Text] [Related]
8. Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis.
Nyskohus LS; Watson AJ; Margison GP; Le Leu RK; Kim SW; Lockett TJ; Head RJ; Young GP; Hu Y
Mutat Res Genet Toxicol Environ Mutagen; 2013 Dec; 758(1-2):80-6. PubMed ID: 24140386
[TBL] [Abstract][Full Text] [Related]
9. A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells.
Senhaji Mouhri Z; Goodfellow E; Jean-Claude B
BMC Cancer; 2017 Aug; 17(1):540. PubMed ID: 28800752
[TBL] [Abstract][Full Text] [Related]
10. The dual role of DNA repair protein MGMT in cancer prevention and treatment.
Bai P; Fan T; Sun G; Wang X; Zhao L; Zhong R
DNA Repair (Amst); 2023 Mar; 123():103449. PubMed ID: 36680944
[TBL] [Abstract][Full Text] [Related]
11. Repair of O6-carboxymethylguanine adducts by O6-methylguanine-DNA methyltransferase in human colon epithelial cells.
Kostka T; Empl MT; Seiwert N; Geisen SM; Hoffmann P; Adam J; Seeger B; Shay JW; Christmann M; Sturla SJ; Fahrer J; Steinberg P
Carcinogenesis; 2021 Aug; 42(8):1110-1118. PubMed ID: 34115837
[TBL] [Abstract][Full Text] [Related]
12. EPIC-0307-mediated selective disruption of PRADX-EZH2 interaction and enhancement of temozolomide sensitivity to glioblastoma via inhibiting DNA repair and MGMT.
Xin L; Tan Y; Zhu Y; Cui X; Wang Q; Zhao J; Tian S; Xu C; Xiao M; Hong B; Xu J; Yuan X; Wang C; Kang C; Fang C
Neuro Oncol; 2023 Nov; 25(11):1976-1988. PubMed ID: 37279651
[TBL] [Abstract][Full Text] [Related]
13. Mismatch repair proteins play a role in ATR activation upon temozolomide treatment in MGMT-methylated glioblastoma.
Ganesa S; Sule A; Sundaram RK; Bindra RS
Sci Rep; 2022 Apr; 12(1):5827. PubMed ID: 35388070
[TBL] [Abstract][Full Text] [Related]
14. Formation and degradation of nitrogen mustard-induced MGMT-DNA crosslinking in 16HBE cells.
Cheng J; Ye F; Dan G; Zhao Y; Zhao J; Zou Z
Toxicology; 2017 Aug; 389():67-73. PubMed ID: 28720507
[TBL] [Abstract][Full Text] [Related]
15. BET protein inhibition sensitizes glioblastoma cells to temozolomide treatment by attenuating MGMT expression.
Tancredi A; Gusyatiner O; Bady P; Buri MC; Lomazzi R; Chiesi D; Messerer M; Hegi ME
Cell Death Dis; 2022 Dec; 13(12):1037. PubMed ID: 36513631
[TBL] [Abstract][Full Text] [Related]
16. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
[TBL] [Abstract][Full Text] [Related]
17. MGMT: a personal perspective.
Mitra S
DNA Repair (Amst); 2007 Aug; 6(8):1064-70. PubMed ID: 17482889
[TBL] [Abstract][Full Text] [Related]
18. NMDA receptor signaling induces the chemoresistance of temozolomide via upregulation of MGMT expression in glioblastoma cells.
Tsuji S; Nakamura S; Shoda K; Yamada T; Shimazawa M; Nakayama N; Iwama T; Hara H
J Neurooncol; 2022 Nov; 160(2):375-388. PubMed ID: 36308592
[TBL] [Abstract][Full Text] [Related]
19. Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
Bobola MS; Kolstoe DD; Blank A; Silber JR
Mol Cancer Ther; 2010 May; 9(5):1208-18. PubMed ID: 20457618
[TBL] [Abstract][Full Text] [Related]
20. Epigenetic Activation of TUSC3 Sensitizes Glioblastoma to Temozolomide Independent of MGMT Promoter Methylation Status.
Wu Q; Berglund AE; Macaulay RJ; Etame AB
Int J Mol Sci; 2023 Oct; 24(20):. PubMed ID: 37894860
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
