BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 36243007)

  • 1. Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element.
    Hall JA; Pokrovskii M; Kroehling L; Kim BR; Kim SY; Wu L; Lee JY; Littman DR
    Immunity; 2022 Nov; 55(11):2027-2043.e9. PubMed ID: 36243007
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SOX-5 activates a novel RORγt enhancer to facilitate experimental autoimmune encephalomyelitis by promoting Th17 cell differentiation.
    Tian Y; Han C; Wei Z; Dong H; Shen X; Cui Y; Fu X; Tian Z; Wang S; Zhou J; Yang D; Sun Y; Yuan J; Ni B; Wu Y
    Nat Commun; 2021 Jan; 12(1):481. PubMed ID: 33473108
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RORγt and RORα signature genes in human Th17 cells.
    Castro G; Liu X; Ngo K; De Leon-Tabaldo A; Zhao S; Luna-Roman R; Yu J; Cao T; Kuhn R; Wilkinson P; Herman K; Nelen MI; Blevitt J; Xue X; Fourie A; Fung-Leung WP
    PLoS One; 2017; 12(8):e0181868. PubMed ID: 28763457
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The AP-1 transcription factor JunB is required for Th17 cell differentiation.
    Yamazaki S; Tanaka Y; Araki H; Kohda A; Sanematsu F; Arasaki T; Duan X; Miura F; Katagiri T; Shindo R; Nakano H; Ito T; Fukui Y; Endo S; Sumimoto H
    Sci Rep; 2017 Dec; 7(1):17402. PubMed ID: 29234109
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling.
    Raveney BJ; Oki S; Yamamura T
    PLoS One; 2013; 8(2):e56595. PubMed ID: 23437182
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms.
    Xiao S; Yosef N; Yang J; Wang Y; Zhou L; Zhu C; Wu C; Baloglu E; Schmidt D; Ramesh R; Lobera M; Sundrud MS; Tsai PY; Xiang Z; Wang J; Xu Y; Lin X; Kretschmer K; Rahl PB; Young RA; Zhong Z; Hafler DA; Regev A; Ghosh S; Marson A; Kuchroo VK
    Immunity; 2014 Apr; 40(4):477-89. PubMed ID: 24745332
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner.
    Sen S; Wang F; Zhang J; He Z; Ma J; Gwack Y; Xu J; Sun Z
    Proc Natl Acad Sci U S A; 2018 Jan; 115(3):E458-E467. PubMed ID: 29282318
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic and pharmacological inhibition of the nuclear receptor RORα regulates T
    Wang R; Campbell S; Amir M; Mosure SA; Bassette MA; Eliason A; Sundrud MS; Kamenecka TM; Solt LA
    Nat Commun; 2021 Jan; 12(1):76. PubMed ID: 33397953
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A two-amino-acid substitution in the transcription factor RORγt disrupts its function in T
    He Z; Ma J; Wang R; Zhang J; Huang Z; Wang F; Sen S; Rothenberg EV; Sun Z
    Nat Immunol; 2017 Oct; 18(10):1128-1138. PubMed ID: 28846085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt.
    Lazarevic V; Chen X; Shim JH; Hwang ES; Jang E; Bolm AN; Oukka M; Kuchroo VK; Glimcher LH
    Nat Immunol; 2011 Jan; 12(1):96-104. PubMed ID: 21151104
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered Expression of Specific Transcription Factors of Th17 (RORγt, RORα) and Treg Lymphocytes (FOXP3) by Peripheral Blood Mononuclear Cells from Patients with Multiple Sclerosis.
    Etesam Z; Nemati M; Ebrahimizadeh MA; Ebrahimi HA; Hajghani H; Khalili T; Frootan R; Zinoddini N; Jafarzadeh A
    J Mol Neurosci; 2016 Sep; 60(1):94-101. PubMed ID: 27370539
    [TBL] [Abstract][Full Text] [Related]  

  • 12. α-Synuclein induces Th17 differentiation and impairs the function and stability of Tregs by promoting RORC transcription in Parkinson's disease.
    Li J; Zhao J; Chen L; Gao H; Zhang J; Wang D; Zou Y; Qin Q; Qu Y; Li J; Xiong Y; Min Z; Yan M; Mao Z; Xue Z
    Brain Behav Immun; 2023 Feb; 108():32-44. PubMed ID: 36343753
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation.
    Liu Z; Cao W; Xu L; Chen X; Zhan Y; Yang Q; Liu S; Chen P; Jiang Y; Sun X; Tao Y; Hu Y; Li C; Wang Q; Wang Y; Chen CD; Shi Y; Zhang X
    J Mol Cell Biol; 2015 Dec; 7(6):505-16. PubMed ID: 25840993
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RORγt expression in mature T
    Chi X; Jin W; Zhao X; Xie T; Shao J; Bai X; Jiang Y; Wang X; Dong C
    Sci Adv; 2022 Aug; 8(34):eabn7774. PubMed ID: 36026450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased peripheral RORα and RORγt mRNA expression is associated with acute-on-chronic hepatitis B liver failure.
    Qi ZX; Wang LY; Fan YC; Zhang JJ; Li T; Wang K
    J Viral Hepat; 2012 Nov; 19(11):811-22. PubMed ID: 23043388
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular mechanisms of T helper 17 cell differentiation: Emerging roles for transcription cofactors.
    Jiang Y; Wang X; Dong C
    Adv Immunol; 2019; 144():121-153. PubMed ID: 31699215
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
    Tan J; Liu H; Huang M; Li N; Tang S; Meng J; Tang S; Zhou H; Kijlstra A; Yang P; Hou S
    Cell Death Dis; 2020 Aug; 11(8):697. PubMed ID: 32829384
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3.
    Tanaka S; Suto A; Iwamoto T; Kashiwakuma D; Kagami S; Suzuki K; Takatori H; Tamachi T; Hirose K; Onodera A; Suzuki J; Ohara O; Yamashita M; Nakayama T; Nakajima H
    J Exp Med; 2014 Aug; 211(9):1857-74. PubMed ID: 25073789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation.
    Chang D; Xing Q; Su Y; Zhao X; Xu W; Wang X; Dong C
    Immunity; 2020 Sep; 53(3):614-626.e4. PubMed ID: 32827457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors.
    Okamoto K; Iwai Y; Oh-Hora M; Yamamoto M; Morio T; Aoki K; Ohya K; Jetten AM; Akira S; Muta T; Takayanagi H
    Nature; 2010 Apr; 464(7293):1381-5. PubMed ID: 20383124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.