BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 36243685)

  • 1. Gamma-secretase inhibitor does not induce cytotoxicity in adult T-cell leukemia cell lines despite NOTCH1 expression.
    Suzuki S; Hourai S; Uozumi K; Uchida Y; Yoshimitsu M; Miho H; Arima N; Ueno SI; Ishitsuka K
    BMC Cancer; 2022 Oct; 22(1):1065. PubMed ID: 36243685
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
    Palomero T; Barnes KC; Real PJ; Glade Bender JL; Sulis ML; Murty VV; Colovai AI; Balbin M; Ferrando AA
    Leukemia; 2006 Jul; 20(7):1279-87. PubMed ID: 16688224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
    De Keersmaecker K; Lahortiga I; Mentens N; Folens C; Van Neste L; Bekaert S; Vandenberghe P; Odero MD; Marynen P; Cools J
    Haematologica; 2008 Apr; 93(4):533-42. PubMed ID: 18322257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia.
    Pancewicz J; Taylor JM; Datta A; Baydoun HH; Waldmann TA; Hermine O; Nicot C
    Proc Natl Acad Sci U S A; 2010 Sep; 107(38):16619-24. PubMed ID: 20823234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenic mutations in the FBXW7 gene of adult T-cell leukemia patients.
    Yeh CH; Bellon M; Pancewicz-Wojtkiewicz J; Nicot C
    Proc Natl Acad Sci U S A; 2016 Jun; 113(24):6731-6. PubMed ID: 27247421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. JAG1 overexpression contributes to Notch1 signaling and the migration of HTLV-1-transformed ATL cells.
    Bellon M; Moles R; Chaib-Mezrag H; Pancewicz J; Nicot C
    J Hematol Oncol; 2018 Sep; 11(1):119. PubMed ID: 30231940
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of Notch1 signaling by HTLV-1 Tax promotes proliferation of adult T-cell leukemia cells.
    Cheng W; Zheng T; Wang Y; Cai K; Wu W; Zhao T; Xu R
    Biochem Biophys Res Commun; 2019 May; 512(3):598-603. PubMed ID: 30914196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 9. T cell acute lymphoblastic leukemia/lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling.
    Pear WS; Aster JC
    Curr Opin Hematol; 2004 Nov; 11(6):426-33. PubMed ID: 15548998
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells.
    Kogoshi H; Sato T; Koyama T; Nara N; Tohda S
    Oncol Rep; 2007 Jul; 18(1):77-80. PubMed ID: 17549349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment.
    López-Nieva P; González-Sánchez L; Cobos-Fernández MÁ; Córdoba R; Santos J; Fernández-Piqueras J
    Oncologist; 2021 Feb; 26(2):e298-e305. PubMed ID: 33191568
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model.
    Yu P; Petrus MN; Ju W; Zhang M; Conlon KC; Nakagawa M; Maeda M; Bamford RN; Waldmann TA
    Leukemia; 2015 Mar; 29(3):556-66. PubMed ID: 25118879
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
    Rao SS; O'Neil J; Liberator CD; Hardwick JS; Dai X; Zhang T; Tyminski E; Yuan J; Kohl NE; Richon VM; Van der Ploeg LH; Carroll PM; Draetta GF; Look AT; Strack PR; Winter CG
    Cancer Res; 2009 Apr; 69(7):3060-8. PubMed ID: 19318552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
    Cullion K; Draheim KM; Hermance N; Tammam J; Sharma VM; Ware C; Nikov G; Krishnamoorthy V; Majumder PK; Kelliher MA
    Blood; 2009 Jun; 113(24):6172-81. PubMed ID: 19246562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis.
    Ishikawa C; Nakachi S; Senba M; Sugai M; Mori N
    Carcinogenesis; 2011 Jan; 32(1):110-9. PubMed ID: 20974684
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia.
    Kaushik B; Pal D; Saha S
    Curr Drug Targets; 2021; 22(15):1789-1798. PubMed ID: 33538669
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Unique T-Cell Receptor Amino Acid Sequence Selected by Human T-Cell Lymphotropic Virus Type 1 Tax
    Ishihara Y; Tanaka Y; Kobayashi S; Kawamura K; Nakasone H; Gomyo A; Hayakawa J; Tamaki M; Akahoshi Y; Harada N; Kusuda M; Kameda K; Ugai T; Wada H; Sakamoto K; Sato M; Terasako-Saito K; Kikuchi M; Kimura SI; Tanihara A; Kako S; Uchimaru K; Kanda Y
    J Virol; 2017 Oct; 91(19):. PubMed ID: 28724766
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition.
    Hounjet J; Habets R; Schaaf MB; Hendrickx TC; Barbeau LMO; Yahyanejad S; Rouschop KM; Groot AJ; Vooijs M
    Oncogene; 2019 Jul; 38(27):5457-5468. PubMed ID: 30967635
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells.
    Satou Y; Yasunaga J; Yoshida M; Matsuoka M
    Proc Natl Acad Sci U S A; 2006 Jan; 103(3):720-5. PubMed ID: 16407133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human T-cell leukemia virus type 1 tax transactivates the matrix metalloproteinase 7 gene via JunD/AP-1 signaling.
    Nakachi S; Nakazato T; Ishikawa C; Kimura R; Mann DA; Senba M; Masuzaki H; Mori N
    Biochim Biophys Acta; 2011 May; 1813(5):731-41. PubMed ID: 21315773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.