114 related articles for article (PubMed ID: 36257461)
1. Enhanced drug delivery by a prodrug approach effectively relieves neuroinflammation in mice.
Montaser AB; Kuiri J; Natunen T; Hruška P; Potěšil D; Auriola S; Hiltunen M; Terasaki T; Lehtonen M; Jalkanen A; Huttunen KM
Life Sci; 2022 Dec; 310():121088. PubMed ID: 36257461
[TBL] [Abstract][Full Text] [Related]
2. Targeting of Perforin Inhibitor into the Brain Parenchyma Via a Prodrug Approach Can Decrease Oxidative Stress and Neuroinflammation and Improve Cell Survival.
Tampio J; Huttunen J; Montaser A; Huttunen KM
Mol Neurobiol; 2020 Nov; 57(11):4563-4577. PubMed ID: 32754897
[TBL] [Abstract][Full Text] [Related]
3. Improved l-Type amino acid transporter 1 (LAT1)-mediated delivery of anti-inflammatory drugs into astrocytes and microglia with reduced prostaglandin production.
Tampio J; Löffler S; Guillon M; Hugele A; Huttunen J; Huttunen KM
Int J Pharm; 2021 May; 601():120565. PubMed ID: 33812973
[TBL] [Abstract][Full Text] [Related]
4. L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells.
Montaser AB; Järvinen J; Löffler S; Huttunen J; Auriola S; Lehtonen M; Jalkanen A; Huttunen KM
ACS Chem Neurosci; 2020 Dec; 11(24):4301-4315. PubMed ID: 33228353
[TBL] [Abstract][Full Text] [Related]
5. L-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia.
Huttunen J; Peltokangas S; Gynther M; Natunen T; Hiltunen M; Auriola S; Ruponen M; Vellonen KS; Huttunen KM
Sci Rep; 2019 Sep; 9(1):12860. PubMed ID: 31492955
[TBL] [Abstract][Full Text] [Related]
6. Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation.
Ye X; Zhu M; Che X; Wang H; Liang XJ; Wu C; Xue X; Yang J
J Neuroinflammation; 2020 Jan; 17(1):18. PubMed ID: 31926553
[TBL] [Abstract][Full Text] [Related]
7. ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway.
Cai L; Gong Q; Qi L; Xu T; Suo Q; Li X; Wang W; Jing Y; Yang D; Xu Z; Yuan F; Tang Y; Yang G; Ding J; Chen H; Tian H
Cell Commun Signal; 2022 Apr; 20(1):56. PubMed ID: 35461293
[TBL] [Abstract][Full Text] [Related]
8. 6-O-angeloylplenolin exerts neuroprotection against lipopolysaccharide-induced neuroinflammation in vitro and in vivo.
Zhou YL; Yan YM; Li SY; He DH; Xiong S; Wei SF; Liu W; Hu L; Wang Q; Pan HF; Cheng YX; Liu YQ
Acta Pharmacol Sin; 2020 Jan; 41(1):10-21. PubMed ID: 31213669
[TBL] [Abstract][Full Text] [Related]
9. Mechanistic Study on the Use of the l-Type Amino Acid Transporter 1 for Brain Intracellular Delivery of Ketoprofen via Prodrug: A Novel Approach Supporting the Development of Prodrugs for Intracellular Targets.
Puris E; Gynther M; de Lange ECM; Auriola S; Hammarlund-Udenaes M; Huttunen KM; Loryan I
Mol Pharm; 2019 Jul; 16(7):3261-3274. PubMed ID: 31180686
[TBL] [Abstract][Full Text] [Related]
10. L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery.
Puris E; Gynther M; Huttunen J; Auriola S; Huttunen KM
Eur J Pharm Sci; 2019 Mar; 129():99-109. PubMed ID: 30625368
[TBL] [Abstract][Full Text] [Related]
11. Hesperetin inhibits neuroinflammation on microglia by suppressing inflammatory cytokines and MAPK pathways.
Jo SH; Kim ME; Cho JH; Lee Y; Lee J; Park YD; Lee JS
Arch Pharm Res; 2019 Aug; 42(8):695-703. PubMed ID: 31327152
[TBL] [Abstract][Full Text] [Related]
12. Pseudane-VII Regulates LPS-Induced Neuroinflammation in Brain Microglia Cells through the Inhibition of iNOS Expression.
Kim ME; Jung I; Na JY; Lee Y; Lee J; Lee JS; Lee JS
Molecules; 2018 Dec; 23(12):. PubMed ID: 30518111
[TBL] [Abstract][Full Text] [Related]
13. Anti-Inflammatory and Neuroprotective Mechanisms of GTS-21, an α7 Nicotinic Acetylcholine Receptor Agonist, in Neuroinflammation and Parkinson's Disease Mouse Models.
Park JE; Leem YH; Park JS; Kim DY; Kang JL; Kim HS
Int J Mol Sci; 2022 Apr; 23(8):. PubMed ID: 35457238
[TBL] [Abstract][Full Text] [Related]
14. Anti-neuroinflammatory effect of Sophoraflavanone G from Sophora alopecuroides in LPS-activated BV2 microglia by MAPK, JAK/STAT and Nrf2/HO-1 signaling pathways.
Guo C; Yang L; Wan CX; Xia YZ; Zhang C; Chen MH; Wang ZD; Li ZR; Li XM; Geng YD; Kong LY
Phytomedicine; 2016 Dec; 23(13):1629-1637. PubMed ID: 27823627
[TBL] [Abstract][Full Text] [Related]
15. Natural bear bile powder suppresses neuroinflammation in lipopolysaccharide-treated mice via regulating TGR5/AKT/NF-κB signaling pathway.
Zhu H; Wang G; Bai Y; Tao Y; Wang L; Yang L; Wu H; Huang F; Shi H; Wu X
J Ethnopharmacol; 2022 May; 289():115063. PubMed ID: 35149130
[TBL] [Abstract][Full Text] [Related]
16. Baicalin mitigates cognitive impairment and protects neurons from microglia-mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF-κB signaling pathway.
Jin X; Liu MY; Zhang DF; Zhong X; Du K; Qian P; Yao WF; Gao H; Wei MJ
CNS Neurosci Ther; 2019 May; 25(5):575-590. PubMed ID: 30676698
[TBL] [Abstract][Full Text] [Related]
17. The Mycobacterial Adjuvant Analogue TDB Attenuates Neuroinflammation via Mincle-Independent PLC-γ1/PKC/ERK Signaling and Microglial Polarization.
Mohanraj M; Sekar P; Liou HH; Chang SF; Lin WW
Mol Neurobiol; 2019 Feb; 56(2):1167-1187. PubMed ID: 29876879
[TBL] [Abstract][Full Text] [Related]
18. DSS-induced inflammation in the colon drives a proinflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod.
Talley S; Valiauga R; Anderson L; Cannon AR; Choudhry MA; Campbell EM
J Neuroinflammation; 2021 Nov; 18(1):263. PubMed ID: 34758843
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and evaluation of a series of non-steroidal anti-inflammatory drug conjugates as novel neuroinflammatory inhibitors.
Xu Z; Wu J; Zheng J; Ma H; Zhang H; Zhen X; Zheng LT; Zhang X
Int Immunopharmacol; 2015 Apr; 25(2):528-37. PubMed ID: 25765352
[TBL] [Abstract][Full Text] [Related]
20. The induction of neuronal death by up-regulated microglial cathepsin H in LPS-induced neuroinflammation.
Fan K; Li D; Zhang Y; Han C; Liang J; Hou C; Xiao H; Ikenaka K; Ma J
J Neuroinflammation; 2015 Mar; 12():54. PubMed ID: 25889123
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]