These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 36259365)

  • 1. Discovery of Anti-tubercular Analogues of Bedaquiline with Modified A-, B- and C-Ring Subunits.
    Barbaro L; Nagalingam G; Triccas JA; Tan L; West NP; Priebbenow DL; Baell JB
    ChemMedChem; 2023 Jan; 18(1):e202200533. PubMed ID: 36259365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel.
    Sutherland HS; Tong AST; Choi PJ; Blaser A; Conole D; Franzblau SG; Lotlikar MU; Cooper CB; Upton AM; Denny WA; Palmer BD
    Bioorg Med Chem; 2019 Apr; 27(7):1292-1307. PubMed ID: 30803745
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline.
    Blaser A; Sutherland HS; Tong AST; Choi PJ; Conole D; Franzblau SG; Cooper CB; Upton AM; Lotlikar M; Denny WA; Palmer BD
    Bioorg Med Chem; 2019 Apr; 27(7):1283-1291. PubMed ID: 30792104
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology.
    Sutherland HS; Tong AST; Choi PJ; Blaser A; Franzblau SG; Cooper CB; Upton AM; Lotlikar M; Denny WA; Palmer BD
    Bioorg Med Chem; 2020 Jan; 28(1):115213. PubMed ID: 31810890
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876-A Less Toxic and More Potent Analogue of Bedaquiline.
    Choi PJ; Conole D; Sutherland HS; Blaser A; Tong AST; Cooper CB; Upton AM; Palmer BD; Denny WA
    Molecules; 2020 Mar; 25(6):. PubMed ID: 32245020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TBAJ-876 Retains Bedaquiline's Activity against Subunits c and ε of
    Sarathy JP; Ragunathan P; Shin J; Cooper CB; Upton AM; Grüber G; Dick T
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31358589
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Current Perspective of ATP Synthase Inhibitors in the Management of the Tuberculosis.
    Divita KM; Khatik GL
    Curr Top Med Chem; 2021; 21(18):1623-1643. PubMed ID: 34517802
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units.
    Choi PJ; Sutherland HS; Tong AST; Blaser A; Franzblau SG; Cooper CB; Lotlikar MU; Upton AM; Guillemont J; Motte M; Queguiner L; Andries K; Van den Broeck W; Denny WA; Palmer BD
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5190-5196. PubMed ID: 29107541
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural Simplification of Bedaquiline: the Discovery of 3-(4-(N,N-Dimethylaminomethyl)phenyl)quinoline-Derived Antitubercular Lead Compounds.
    He C; Preiss L; Wang B; Fu L; Wen H; Zhang X; Cui H; Meier T; Yin D
    ChemMedChem; 2017 Jan; 12(2):106-119. PubMed ID: 27792278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles.
    Sutherland HS; Tong AST; Choi PJ; Conole D; Blaser A; Franzblau SG; Cooper CB; Upton AM; Lotlikar MU; Denny WA; Palmer BD
    Bioorg Med Chem; 2018 May; 26(8):1797-1809. PubMed ID: 29482950
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
    Zhang Y; Lai Y; Zhou S; Ran T; Zhang Y; Zhao Z; Feng Z; Yu L; Xu J; Shi K; Wang J; Pang Y; Li L; Chen H; Guddat LW; Gao Y; Liu F; Rao Z; Gong H
    Nature; 2024 Jul; 631(8020):409-414. PubMed ID: 38961288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative Efficacy of the Novel Diarylquinoline TBAJ-876 and Bedaquiline against a Resistant
    Almeida D; Converse PJ; Li SY; Upton AM; Fotouhi N; Nuermberger EL
    Antimicrob Agents Chemother; 2021 Nov; 65(12):e0141221. PubMed ID: 34570644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis and Biological Evaluation of Anti-tuberculosis Agents based on Bedaquiline Structure.
    Wu C; Luo J; Wu M; Meng F; Cai Z; Chen Y; Sun T
    Med Chem; 2020; 16(5):703-714. PubMed ID: 31203803
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of pyridine-derived bedaquiline analogues containing modifications at the A-ring subunit.
    Barbaro L; Nagalingam G; Triccas JA; Tan L; West NP; Baell JB; Priebbenow DL
    RSC Med Chem; 2021 Jun; 12(6):943-959. PubMed ID: 34223160
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TMC207 becomes bedaquiline, a new anti-TB drug.
    Palomino JC; Martin A
    Future Microbiol; 2013 Sep; 8(9):1071-80. PubMed ID: 24020736
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A structural insight of bedaquiline for the cardiotoxicity and hepatotoxicity.
    Patel H; Pawara R; Pawara K; Ahmed F; Shirkhedkar A; Surana S
    Tuberculosis (Edinb); 2019 Jul; 117():79-84. PubMed ID: 31378273
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bedaquiline: a novel antitubercular agent for the treatment of multidrug-resistant tuberculosis.
    Worley MV; Estrada SJ
    Pharmacotherapy; 2014 Nov; 34(11):1187-97. PubMed ID: 25203970
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimizing cardio, hepato and phospholipidosis toxicity of the Bedaquiline by chemoinformatics and molecular modelling approach.
    Girase R; Ahmad I; Pawara R; Patel H
    SAR QSAR Environ Res; 2022 Mar; 33(3):215-235. PubMed ID: 35225110
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Triple Mycobacterial ATP-synthase mutations impedes Bedaquiline binding: Atomistic and structural perspectives.
    Salifu EY; Agoni C; Olotu FA; Soliman MES
    Comput Biol Chem; 2020 Apr; 85():107204. PubMed ID: 31981966
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug's Uncoupler Activity.
    Sarathy JP; Ragunathan P; Cooper CB; Upton AM; Grüber G; Dick T
    Antimicrob Agents Chemother; 2020 Jan; 64(2):. PubMed ID: 31712198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.