197 related articles for article (PubMed ID: 36266286)
1. p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.
Murai K; Dentro S; Ong SH; Sood R; Fernandez-Antoran D; Herms A; Kostiou V; Abnizova I; Hall BA; Gerstung M; Jones PH
Nat Commun; 2022 Oct; 13(1):6206. PubMed ID: 36266286
[TBL] [Abstract][Full Text] [Related]
2. Loss of wild-type p53 promotes mutant p53-driven metastasis through acquisition of survival and tumor-initiating properties.
Nakayama M; Hong CP; Oshima H; Sakai E; Kim SJ; Oshima M
Nat Commun; 2020 May; 11(1):2333. PubMed ID: 32393735
[TBL] [Abstract][Full Text] [Related]
3. Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.
Murai K; Skrupskelyte G; Piedrafita G; Hall M; Kostiou V; Ong SH; Nagy T; Cagan A; Goulding D; Klein AM; Hall BA; Jones PH
Cell Stem Cell; 2018 Nov; 23(5):687-699.e8. PubMed ID: 30269904
[TBL] [Abstract][Full Text] [Related]
4. Copy-neutral loss of heterozygosity at the p53 locus in carcinogenesis of esophageal squamous cell carcinomas associated with p53 mutations.
Saeki H; Kitao H; Yoshinaga K; Nakanoko T; Kubo N; Kakeji Y; Morita M; Maehara Y
Clin Cancer Res; 2011 Apr; 17(7):1731-40. PubMed ID: 21325068
[TBL] [Abstract][Full Text] [Related]
5. Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.
Fernandez-Antoran D; Piedrafita G; Murai K; Ong SH; Herms A; Frezza C; Jones PH
Cell Stem Cell; 2019 Sep; 25(3):329-341.e6. PubMed ID: 31327664
[TBL] [Abstract][Full Text] [Related]
6. Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
Schofield HK; Zeller J; Espinoza C; Halbrook CJ; Del Vecchio A; Magnuson B; Fabo T; Cali Daylan AE; Kovalenko I; Lee HJ; Yan W; Feng Y; Karim SA; Kremer DM; Kumar-Sinha C; Lyssiotis CA; Ljungman M; Morton JP; Galbán S; Fearon ER; Pasca di Magliano M
JCI Insight; 2018 Jan; 3(2):. PubMed ID: 29367463
[TBL] [Abstract][Full Text] [Related]
7. Simulations reveal that different responses to cell crowding determine the expansion of
Kostiou V; Hall MWJ; Jones PH; Hall BA
J R Soc Interface; 2021 Oct; 18(183):20210607. PubMed ID: 34637643
[TBL] [Abstract][Full Text] [Related]
8. Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in breast cancer cells.
Ghaleb A; Padellan M; Marchenko N
Breast Cancer Res; 2020 Dec; 22(1):133. PubMed ID: 33267874
[TBL] [Abstract][Full Text] [Related]
9. Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
Abby E; Dentro SC; Hall MWJ; Fowler JC; Ong SH; Sood R; Herms A; Piedrafita G; Abnizova I; Siebel CW; Gerstung M; Hall BA; Jones PH
Nat Genet; 2023 Feb; 55(2):232-245. PubMed ID: 36658434
[TBL] [Abstract][Full Text] [Related]
10. Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's oesophagus.
Leedham SJ; Preston SL; McDonald SA; Elia G; Bhandari P; Poller D; Harrison R; Novelli MR; Jankowski JA; Wright NA
Gut; 2008 Aug; 57(8):1041-8. PubMed ID: 18305067
[TBL] [Abstract][Full Text] [Related]
11. Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Colom B; Herms A; Hall MWJ; Dentro SC; King C; Sood RK; Alcolea MP; Piedrafita G; Fernandez-Antoran D; Ong SH; Fowler JC; Mahbubani KT; Saeb-Parsy K; Gerstung M; Hall BA; Jones PH
Nature; 2021 Oct; 598(7881):510-514. PubMed ID: 34646013
[TBL] [Abstract][Full Text] [Related]
12. UVB-induced apoptosis drives clonal expansion during skin tumor development.
Zhang W; Hanks AN; Boucher K; Florell SR; Allen SM; Alexander A; Brash DE; Grossman D
Carcinogenesis; 2005 Jan; 26(1):249-57. PubMed ID: 15498793
[TBL] [Abstract][Full Text] [Related]
13. The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.
Xiong S; Pant V; Zhang Y; Aryal NK; You MJ; Kusewitt D; Lozano G
J Pathol; 2017 Mar; 241(4):501-510. PubMed ID: 27925213
[TBL] [Abstract][Full Text] [Related]
14. Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
Tang J; Feng Y; Kuick R; Green M; Green M; Sakamoto N; Kurosu Y; Lin J; Cho KR; Fearon ER
Lab Invest; 2019 Oct; 99(10):1454-1469. PubMed ID: 31148594
[TBL] [Abstract][Full Text] [Related]
15. Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations.
Zhang W; Remenyik E; Zelterman D; Brash DE; Wikonkal NM
Proc Natl Acad Sci U S A; 2001 Nov; 98(24):13948-53. PubMed ID: 11707578
[TBL] [Abstract][Full Text] [Related]
16. p53 Gene mutation and genetic instability in superficial multifocal esophageal squamous cell carcinoma.
Fujiki T; Haraoka S; Yoshioka S; Ohshima K; Iwashita A; Kikuchi M
Int J Oncol; 2002 Apr; 20(4):669-79. PubMed ID: 11894109
[TBL] [Abstract][Full Text] [Related]
17. Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
Colom B; Alcolea MP; Piedrafita G; Hall MWJ; Wabik A; Dentro SC; Fowler JC; Herms A; King C; Ong SH; Sood RK; Gerstung M; Martincorena I; Hall BA; Jones PH
Nat Genet; 2020 Jun; 52(6):604-614. PubMed ID: 32424351
[TBL] [Abstract][Full Text] [Related]
18. Skin precancer.
Brash DE; Pontén J
Cancer Surv; 1998; 32():69-113. PubMed ID: 10489624
[TBL] [Abstract][Full Text] [Related]
19. BRCA2 and TP53 collaborate in tumorigenesis in zebrafish.
Shive HR; West RR; Embree LJ; Golden CD; Hickstein DD
PLoS One; 2014; 9(1):e87177. PubMed ID: 24489863
[TBL] [Abstract][Full Text] [Related]
20. p53-mutant clones and field effects in Barrett's esophagus.
Prevo LJ; Sanchez CA; Galipeau PC; Reid BJ
Cancer Res; 1999 Oct; 59(19):4784-7. PubMed ID: 10519384
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]