BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 36282120)

  • 1. Structural dynamics of the N-terminal SH2 domain of PI3K in its free and CD28-bound states.
    Hosoe Y; Miyanoiri Y; Re S; Ochi S; Asahina Y; Kawakami T; Kuroda M; Mizuguchi K; Oda M
    FEBS J; 2023 May; 290(9):2366-2378. PubMed ID: 36282120
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins.
    Inaba S; Numoto N; Ogawa S; Morii H; Ikura T; Abe R; Ito N; Oda M
    J Biol Chem; 2017 Jan; 292(3):1052-1060. PubMed ID: 27927989
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains.
    Iiyama M; Numoto N; Ogawa S; Kuroda M; Morii H; Abe R; Ito N; Oda M
    Mol Immunol; 2021 Mar; 131():51-59. PubMed ID: 33386150
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of CD28 binding to SH2 domains of Grb2 and PI3K by trisubstituted carboranes for T-cell activation.
    Ogawa S; Asawa Y; Iiyama M; Yoshimori A; Nakamura H; Oda M
    Bioorg Med Chem Lett; 2022 Dec; 78():129049. PubMed ID: 36356833
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28.
    Higo K; Ikura T; Oda M; Morii H; Takahashi J; Abe R; Ito N
    PLoS One; 2013; 8(9):e74482. PubMed ID: 24098653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes.
    Parry RV; Rumbley CA; Vandenberghe LH; June CH; Riley JL
    J Immunol; 2003 Jul; 171(1):166-74. PubMed ID: 12816995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase.
    Siegal G; Davis B; Kristensen SM; Sankar A; Linacre J; Stein RC; Panayotou G; Waterfield MD; Driscoll PC
    J Mol Biol; 1998 Feb; 276(2):461-78. PubMed ID: 9512716
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction.
    Okkenhaug K; Rottapel R
    J Biol Chem; 1998 Aug; 273(33):21194-202. PubMed ID: 9694876
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural Determinants of Phosphopeptide Binding to the N-Terminal Src Homology 2 Domain of the SHP2 Phosphatase.
    Anselmi M; Calligari P; Hub JS; Tartaglia M; Bocchinfuso G; Stella L
    J Chem Inf Model; 2020 Jun; 60(6):3157-3171. PubMed ID: 32395997
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains.
    Yu J; Wjasow C; Backer JM
    J Biol Chem; 1998 Nov; 273(46):30199-203. PubMed ID: 9804776
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling.
    Kim HH; Tharayil M; Rudd CE
    J Biol Chem; 1998 Jan; 273(1):296-301. PubMed ID: 9417079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28.
    Ellis JH; Ashman C; Burden MN; Kilpatrick KE; Morse MA; Hamblin PA
    J Immunol; 2000 Jun; 164(11):5805-14. PubMed ID: 10820259
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the gab2 pleckstrin homology domain.
    Parry RV; Whittaker GC; Sims M; Edmead CE; Welham MJ; Ward SG
    J Immunol; 2006 Jan; 176(1):594-602. PubMed ID: 16365455
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation.
    Raab M; Cai YC; Bunnell SC; Heyeck SD; Berg LJ; Rudd CE
    Proc Natl Acad Sci U S A; 1995 Sep; 92(19):8891-5. PubMed ID: 7568038
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ALX Src homology 2 domain is both necessary and sufficient to inhibit T cell receptor/CD28-mediated up-regulation of RE/AP.
    Shapiro MJ; Powell P; Ndubuizu A; Nzerem C; Shapiro VS
    J Biol Chem; 2004 Sep; 279(39):40647-52. PubMed ID: 15284240
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.
    Higo K; Oda M; Morii H; Takahashi J; Harada Y; Ogawa S; Abe R
    Immunol Invest; 2014; 43(3):278-91. PubMed ID: 24475931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Backbone dynamics of the C-terminal SH2 domain of the p85alpha subunit of phosphoinositide 3-kinase: effect of phosphotyrosine-peptide binding and characterization of slow conformational exchange processes.
    Kristensen SM; Siegal G; Sankar A; Driscoll PC
    J Mol Biol; 2000 Jun; 299(3):771-88. PubMed ID: 10835283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit.
    Shekar SC; Wu H; Fu Z; Yip SC; Nagajyothi ; Cahill SM; Girvin ME; Backer JM
    J Biol Chem; 2005 Jul; 280(30):27850-5. PubMed ID: 15932879
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
    van der Geer P; Wiley S; Lai VK; Olivier JP; Gish GD; Stephens R; Kaplan D; Shoelson S; Pawson T
    Curr Biol; 1995 Apr; 5(4):404-12. PubMed ID: 7542991
    [TBL] [Abstract][Full Text] [Related]  

  • 20. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif.
    Prasad KV; Cai YC; Raab M; Duckworth B; Cantley L; Shoelson SE; Rudd CE
    Proc Natl Acad Sci U S A; 1994 Mar; 91(7):2834-8. PubMed ID: 8146197
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.