161 related articles for article (PubMed ID: 36283223)
21. Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Murray KA; Hu CJ; Pan H; Lu J; Abskharon R; Bowler JT; Rosenberg GM; Williams CK; Elezi G; Balbirnie M; Faull KF; Vinters HV; Seidler PM; Eisenberg DS
Proc Natl Acad Sci U S A; 2023 Feb; 120(7):e2217835120. PubMed ID: 36757890
[TBL] [Abstract][Full Text] [Related]
22. The Parkinson's disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release.
Apicco DJ; Shlevkov E; Nezich CL; Tran DT; Guilmette E; Nicholatos JW; Bantle CM; Chen Y; Glajch KE; Abraham NA; Dang LT; Kaynor GC; Tsai EA; Nguyen KH; Groot J; Liu Y; Weihofen A; Hurt JA; Runz H; Hirst WD
Proc Natl Acad Sci U S A; 2021 Jan; 118(1):. PubMed ID: 33443159
[TBL] [Abstract][Full Text] [Related]
23. PTEN-Induced Putative Kinase 1 Dysfunction Accelerates Synucleinopathy.
Nguyen TT; Kim YJ; Lai TT; Nguyen PT; Koh YH; Nguyen LTN; Ma HI; Kim YE
J Parkinsons Dis; 2022; 12(4):1201-1217. PubMed ID: 35253778
[TBL] [Abstract][Full Text] [Related]
24. Inhibition of α-synuclein aggregation by MT101-5 is neuroprotective in mouse models of Parkinson's disease.
Kim S; Choi JG; Kim SW; Park SC; Kang YR; Park DS; Son M; Lee CH
Biomed Pharmacother; 2022 Oct; 154():113637. PubMed ID: 36058149
[TBL] [Abstract][Full Text] [Related]
25. Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy.
Chatterjee D; Sanchez DS; Quansah E; Rey NL; George S; Becker K; Madaj Z; Steiner JA; Ma J; Escobar Galvis ML; Kordower JH; Brundin P
J Parkinsons Dis; 2019; 9(2):315-326. PubMed ID: 30932894
[TBL] [Abstract][Full Text] [Related]
26. NADPH oxidase 1 mediates α-synucleinopathy in Parkinson's disease.
Cristóvão AC; Guhathakurta S; Bok E; Je G; Yoo SD; Choi DH; Kim YS
J Neurosci; 2012 Oct; 32(42):14465-77. PubMed ID: 23077033
[TBL] [Abstract][Full Text] [Related]
27. ATPase Thorase Deficiency Causes α-Synucleinopathy and Parkinson's Disease-like Behavior.
Gao F; Zhang H; Yang J; Cai M; Yang Q; Wang H; Xu Y; Chen H; Hu Y; He W; Zhang J
Cells; 2022 Sep; 11(19):. PubMed ID: 36230952
[TBL] [Abstract][Full Text] [Related]
28. Inhibition of copper transporter 1 prevents α-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson's disease.
Gou DH; Huang TT; Li W; Gao XD; Haikal C; Wang XH; Song DY; Liang X; Zhu L; Tang Y; Ding C; Li JY
Redox Biol; 2021 Jan; 38():101795. PubMed ID: 33232911
[TBL] [Abstract][Full Text] [Related]
29. Alpha-synucleinopathy reduces NMNAT3 protein levels and neurite formation that can be rescued by targeting the NAD+ pathway.
Parsons RB; Kocinaj A; Ruiz Pulido G; Prendergast SA; Parsons AE; Facey PD; Hirth F
Hum Mol Genet; 2022 Aug; 31(17):2918-2933. PubMed ID: 35397003
[TBL] [Abstract][Full Text] [Related]
30. MicroRNA-7 Protects Against Neurodegeneration Induced by α-Synuclein Preformed Fibrils in the Mouse Brain.
Zhang J; Zhao M; Yan R; Liu J; Maddila S; Junn E; Mouradian MM
Neurotherapeutics; 2021 Oct; 18(4):2529-2540. PubMed ID: 34697773
[TBL] [Abstract][Full Text] [Related]
31. Nur77 increases mitophagy and decreases aggregation of α-synuclein by modulating the p-c-Abl/p-PHB2 Y121 in α-synuclein PFF SH-SY5Y cells and mice.
Yin S; Shen M; Zhang Y; Wu J; Song R; Lai X; Tian Z; Wang T; Jin W; Yan J
Eur J Med Chem; 2024 Mar; 268():116251. PubMed ID: 38422699
[TBL] [Abstract][Full Text] [Related]
32. Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
Yang ZX; Zhang Y; Wang Q; Zhang L; Liu YF; Zhang Y; Ren Y; Zhou C; Gao HW; Zhang NX; Feng LY
Acta Pharmacol Sin; 2024 Jan; 45(1):36-51. PubMed ID: 37684382
[TBL] [Abstract][Full Text] [Related]
33. LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy.
Schwab K; Frahm S; Magbagbeolu M; Horsley D; Goatman EA; Melis V; Theuring F; Ishaq A; Storey JMD; Harrington CR; Wischik CM; Riedel G
Eur J Pharmacol; 2024 May; 970():176505. PubMed ID: 38503400
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector-Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain.
Svarcbahs R; Julku UH; Myöhänen TT
J Neurosci; 2016 Dec; 36(49):12485-12497. PubMed ID: 27927963
[TBL] [Abstract][Full Text] [Related]
35. The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson's disease mouse model.
Lee S; Kim S; Park YJ; Yun SP; Kwon SH; Kim D; Kim DY; Shin JS; Cho DJ; Lee GY; Ju HS; Yun HJ; Park JH; Kim WR; Jung EA; Lee S; Ko HS
Hum Mol Genet; 2018 Jul; 27(13):2344-2356. PubMed ID: 29897434
[TBL] [Abstract][Full Text] [Related]
36. Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model: Effects of hydromethylthionine.
Schwab K; Chasapopoulou Z; Frahm S; Magbagbeolu M; Cranston A; Harrington CR; Wischik CM; Theuring F; Riedel G
Cell Signal; 2022 Sep; 97():110386. PubMed ID: 35709886
[TBL] [Abstract][Full Text] [Related]
37. Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Patterson JR; Duffy MF; Kemp CJ; Howe JW; Collier TJ; Stoll AC; Miller KM; Patel P; Levine N; Moore DJ; Luk KC; Fleming SM; Kanaan NM; Paumier KL; El-Agnaf OMA; Sortwell CE
Neurobiol Dis; 2019 Oct; 130():104525. PubMed ID: 31276792
[TBL] [Abstract][Full Text] [Related]
38. Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy.
Ardah MT; Eid N; Kitada T; Haque ME
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948195
[TBL] [Abstract][Full Text] [Related]
39. Toxic Oligomeric Alpha-Synuclein Variants Present in Human Parkinson's Disease Brains Are Differentially Generated in Mammalian Cell Models.
Xin W; Emadi S; Williams S; Liu Q; Schulz P; He P; Alam NB; Wu J; Sierks MR
Biomolecules; 2015 Jul; 5(3):1634-51. PubMed ID: 26287258
[TBL] [Abstract][Full Text] [Related]
40. The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
Sharma N; Rao SP; Kalivendi SV
Free Radic Biol Med; 2019 May; 135():28-37. PubMed ID: 30796974
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
