BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 36284196)

  • 1. The autophagy inducer SMER28 attenuates microtubule dynamics mediating neuroprotection.
    Kirchenwitz M; Stahnke S; Grunau K; Melcher L; van Ham M; Rottner K; Steffen A; Stradal TEB
    Sci Rep; 2022 Oct; 12(1):17805. PubMed ID: 36284196
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SMER28 Attenuates Dopaminergic Toxicity Mediated by 6-Hydroxydopamine in the Rats via Modulating Oxidative Burdens and Autophagy-Related Parameters.
    Darabi S; Noori-Zadeh A; Rajaei F; Abbaszadeh HA; Bakhtiyari S; Roozbahany NA
    Neurochem Res; 2018 Dec; 43(12):2313-2323. PubMed ID: 30288644
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta.
    Kirchenwitz M; Stahnke S; Prettin S; Borowiak M; Menke L; Sieben C; Birchmeier C; Rottner K; Stradal TEB; Steffen A
    Cells; 2022 May; 11(10):. PubMed ID: 35626685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuroprotection Through Rapamycin-Induced Activation of Autophagy and PI3K/Akt1/mTOR/CREB Signaling Against Amyloid-β-Induced Oxidative Stress, Synaptic/Neurotransmission Dysfunction, and Neurodegeneration in Adult Rats.
    Singh AK; Kashyap MP; Tripathi VK; Singh S; Garg G; Rizvi SI
    Mol Neurobiol; 2017 Oct; 54(8):5815-5828. PubMed ID: 27660271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dysregulation of autophagy in melanocytes contributes to hypopigmented macules in tuberous sclerosis complex.
    Yang F; Yang L; Wataya-Kaneda M; Hasegawa J; Yoshimori T; Tanemura A; Tsuruta D; Katayama I
    J Dermatol Sci; 2018 Feb; 89(2):155-164. PubMed ID: 29146131
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms.
    Clark AE; Sabalza M; Gordts PLSM; Spector DH
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29237845
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies.
    Harris-White ME; Ferbas KG; Johnson MF; Eslami P; Poteshkina A; Venkova K; Christov A; Hensley K
    Neurobiol Dis; 2015 Dec; 84():60-8. PubMed ID: 25779968
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SMER28 is a mTOR-independent small molecule enhancer of autophagy that protects mouse bone marrow and liver against radiotherapy.
    Koukourakis MI; Giatromanolaki A; Fylaktakidou K; Sivridis E; Zois CE; Kalamida D; Mitrakas A; Pouliliou S; Karagounis IV; Simopoulos K; Ferguson DJP; Harris AL
    Invest New Drugs; 2018 Oct; 36(5):773-781. PubMed ID: 29387992
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dexmedetomidine Protects Against Oxygen-Glucose Deprivation-Induced Injury Through Inducing Astrocytes Autophagy via TSC2/mTOR Pathway.
    Zhu C; Zhou Q; Luo C; Chen Y
    Neuromolecular Med; 2020 Jun; 22(2):210-217. PubMed ID: 31654225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the PI3K/Akt/mTOR pathway.
    Chen A; Xiong LJ; Tong Y; Mao M
    Mol Med Rep; 2013 Oct; 8(4):1011-6. PubMed ID: 23942837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carnosic Acid Attenuates 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells by Inducing Autophagy Through an Enhanced Interaction of Parkin and Beclin1.
    Lin CY; Tsai CW
    Mol Neurobiol; 2017 May; 54(4):2813-2822. PubMed ID: 27013469
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapamycin induces of protective autophagy in vascular endothelial cells exposed to oxygen-glucose deprivation.
    Urbanek T; Kuczmik W; Basta-Kaim A; Gabryel B
    Brain Res; 2014 Mar; 1553():1-11. PubMed ID: 24462935
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hydrogen-saturated saline mediated neuroprotection through autophagy via PI3K/AKT/mTOR pathway in early and medium stages of rotenone-induced Parkinson's disease rats.
    Zhang Z; Sun X; Wang K; Yu Y; Zhang L; Zhang K; Gu J; Yuan X; Song G
    Brain Res Bull; 2021 Jul; 172():1-13. PubMed ID: 33838212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies.
    Sarkar S; Ravikumar B; Floto RA; Rubinsztein DC
    Cell Death Differ; 2009 Jan; 16(1):46-56. PubMed ID: 18636076
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy is a protective response to ethanol neurotoxicity.
    Chen G; Ke Z; Xu M; Liao M; Wang X; Qi Y; Zhang T; Frank JA; Bower KA; Shi X; Luo J
    Autophagy; 2012 Nov; 8(11):1577-89. PubMed ID: 22874567
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
    Sarkar S; Davies JE; Huang Z; Tunnacliffe A; Rubinsztein DC
    J Biol Chem; 2007 Feb; 282(8):5641-52. PubMed ID: 17182613
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.
    Kinghorn KJ; Grönke S; Castillo-Quan JI; Woodling NS; Li L; Sirka E; Gegg M; Mills K; Hardy J; Bjedov I; Partridge L
    J Neurosci; 2016 Nov; 36(46):11654-11670. PubMed ID: 27852774
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mammalian target of Rapamycin inhibition and mycobacterial survival are uncoupled in murine macrophages.
    Zullo AJ; Jurcic Smith KL; Lee S
    BMC Biochem; 2014 Feb; 15():4. PubMed ID: 24528777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage.
    Baek SH; Noh AR; Kim KA; Akram M; Shin YJ; Kim ES; Yu SW; Majid A; Bae ON
    Stroke; 2014 Aug; 45(8):2438-2443. PubMed ID: 24938837
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
    Sarkar S; Perlstein EO; Imarisio S; Pineau S; Cordenier A; Maglathlin RL; Webster JA; Lewis TA; O'Kane CJ; Schreiber SL; Rubinsztein DC
    Nat Chem Biol; 2007 Jun; 3(6):331-8. PubMed ID: 17486044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.