234 related articles for article (PubMed ID: 36288719)
21. Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
Robinson GW; Orr BA; Wu G; Gururangan S; Lin T; Qaddoumi I; Packer RJ; Goldman S; Prados MD; Desjardins A; Chintagumpala M; Takebe N; Kaste SC; Rusch M; Allen SJ; Onar-Thomas A; Stewart CF; Fouladi M; Boyett JM; Gilbertson RJ; Curran T; Ellison DW; Gajjar A
J Clin Oncol; 2015 Aug; 33(24):2646-54. PubMed ID: 26169613
[TBL] [Abstract][Full Text] [Related]
22. The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors.
Mille F; Tamayo-Orrego L; Lévesque M; Remke M; Korshunov A; Cardin J; Bouchard N; Izzi L; Kool M; Northcott PA; Taylor MD; Pfister SM; Charron F
Dev Cell; 2014 Oct; 31(1):34-47. PubMed ID: 25263791
[TBL] [Abstract][Full Text] [Related]
23. Immunohistochemical evaluation of Sonic Hedgehog signaling pathway proteins (Shh, Ptch1, Ptch2, Smo, Gli1, Gli2, and Gli3) in sporadic and syndromic odontogenic keratocysts.
Hoyos Cadavid AM; Kaminagakura E; Rodrigues MFSD; Pinto CAL; Teshima THN; Alves FA
Clin Oral Investig; 2019 Jan; 23(1):153-159. PubMed ID: 29564556
[TBL] [Abstract][Full Text] [Related]
24. An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.
Wijaya J; Vo BT; Liu J; Xu B; Wu G; Wang Y; Peng J; Zhang J; Janke LJ; Orr BA; Yu J; Roussel MF; Schuetz JD
Cancer Res; 2020 Apr; 80(7):1524-1537. PubMed ID: 31948942
[TBL] [Abstract][Full Text] [Related]
25. STAT3 is required for Smo-dependent signaling and mediates Smo-targeted treatment resistance and tumorigenesis in Shh medulloblastoma.
Yuan L; Zhang H; Liu J; Malhotra A; Dey A; Yu B; Jella KK; McSwain LF; Schniederjan MJ; MacDonald TJ
Mol Oncol; 2022 Feb; 16(4):1009-1025. PubMed ID: 34482626
[TBL] [Abstract][Full Text] [Related]
26. Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.
Purzner T; Purzner J; Buckstaff T; Cozza G; Gholamin S; Rusert JM; Hartl TA; Sanders J; Conley N; Ge X; Langan M; Ramaswamy V; Ellis L; Litzenburger U; Bolin S; Theruvath J; Nitta R; Qi L; Li XN; Li G; Taylor MD; Wechsler-Reya RJ; Pinna LA; Cho YJ; Fuller MT; Elias JE; Scott MP
Sci Signal; 2018 Sep; 11(547):. PubMed ID: 30206138
[TBL] [Abstract][Full Text] [Related]
27. Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.
Shahi MH; Afzal M; Sinha S; Eberhart CG; Rey JA; Fan X; Castresana JS
BMC Cancer; 2010 Nov; 10():614. PubMed ID: 21059263
[TBL] [Abstract][Full Text] [Related]
28. Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma.
Robinson MH; Maximov V; Lallani S; Farooq H; Taylor MD; Read RD; Kenney AM
Sci Rep; 2019 Sep; 9(1):13611. PubMed ID: 31541170
[TBL] [Abstract][Full Text] [Related]
29. Low Expression of the
de Araújo MA; Malafaia O; Ribas Filho JM; Fratini L; Roesler R; Isolan GR
Int J Mol Sci; 2023 Jul; 24(14):. PubMed ID: 37511358
[TBL] [Abstract][Full Text] [Related]
30. Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
Liu Y; Yuelling LW; Wang Y; Du F; Gordon RE; O'Brien JA; Ng JMY; Robins S; Lee EH; Liu H; Curran T; Yang ZJ
Cancer Res; 2017 Dec; 77(23):6692-6703. PubMed ID: 28986380
[TBL] [Abstract][Full Text] [Related]
31. Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks.
Po A; Abballe L; Sabato C; Gianno F; Chiacchiarini M; Catanzaro G; De Smaele E; Giangaspero F; Ferretti E; Miele E; Besharat ZM
Int J Mol Sci; 2018 Aug; 19(8):. PubMed ID: 30096798
[TBL] [Abstract][Full Text] [Related]
32. Genetic ablation of Gpr37l1 delays tumor occurrence in Ptch1
Di Pietro C; La Sala G; Matteoni R; Marazziti D; Tocchini-Valentini GP
Exp Neurol; 2019 Feb; 312():33-42. PubMed ID: 30452905
[TBL] [Abstract][Full Text] [Related]
33. Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
Pritchard JI; Olson JM
Cancer Genet Cytogenet; 2008 Jan; 180(1):47-50. PubMed ID: 18068533
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.
Rodriguez-Blanco J; Pednekar L; Penas C; Li B; Martin V; Long J; Lee E; Weiss WA; Rodriguez C; Mehrdad N; Nguyen DM; Ayad NG; Rai P; Capobianco AJ; Robbins DJ
Oncogene; 2017 Nov; 36(45):6306-6314. PubMed ID: 28714964
[TBL] [Abstract][Full Text] [Related]
35. IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma.
Kunhiraman H; McSwain L; Shahab SW; Gershon TR; MacDonald TJ; Kenney AM
Acta Neuropathol Commun; 2023 Apr; 11(1):62. PubMed ID: 37029430
[TBL] [Abstract][Full Text] [Related]
36. Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma.
Li Y; Wang H; Sun B; Su G; Cang Y; Zhao L; Zhao S; Li Y; Mao B; Ma P
Cell Death Dis; 2023 Aug; 14(8):494. PubMed ID: 37537194
[TBL] [Abstract][Full Text] [Related]
37. p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
Wei Y; Maximov V; Morrissy SA; Taylor MD; Pallas DC; Kenney AM
Mol Cancer Res; 2019 Jan; 17(1):186-198. PubMed ID: 30224541
[TBL] [Abstract][Full Text] [Related]
38. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD
Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822
[TBL] [Abstract][Full Text] [Related]
39. FANCD2 deficiency sensitizes SHH medulloblastoma to radiotherapy via ferroptosis.
Zhou H; Wang YX; Wu M; Lan X; Xiang D; Cai R; Ma Q; Miao J; Fang X; Wang J; Luo D; He Z; Cui Y; Liang P; Wang Y; Bian XW
J Pathol; 2024 Apr; 262(4):427-440. PubMed ID: 38229567
[TBL] [Abstract][Full Text] [Related]
40. Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.
Korshunov A; Okonechnikov K; Stichel D; Ryzhova M; Schrimpf D; Sahm F; Sievers P; Absalyamova O; Zheludkova O; Golanov A; Jones DTW; Pfister SM; von Deimling A; Kool M
Neuro Oncol; 2021 Sep; 23(9):1576-1585. PubMed ID: 33589929
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
