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11. Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention. Kawaguchi K; Han Q; Li S; Tan Y; Igarashi K; Kiyuna T; Miyake K; Miyake M; Chmielowski B; Nelson SD; Russell TA; Dry SM; Li Y; Singh AS; Eckardt MA; Unno M; Eilber FC; Hoffman RM Cell Cycle; 2018; 17(3):356-361. PubMed ID: 29187018 [TBL] [Abstract][Full Text] [Related]
12. Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma. Higuchi T; Oshiro H; Miyake K; Sugisawa N; Han Q; Tan Y; Park J; Zhang Z; Razmjooei S; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Bouvet M; Chawla SP; Singh SR; Tsuchiya H; Hoffman RM Anticancer Res; 2019 Sep; 39(9):4653-4657. PubMed ID: 31519563 [TBL] [Abstract][Full Text] [Related]
13. High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer. Hoffman RM; Murakami T; Kawaguchi K; Igarashi K; Tan Y; Li S; Han Q Methods Mol Biol; 2019; 1866():149-161. PubMed ID: 30725414 [TBL] [Abstract][Full Text] [Related]
14. Response of Triple-negative Breast Cancer Liver Metastasis to Oral Recombinant Methioninase in a Patient-derived Orthotopic Xenograft (PDOX) Model. Lim HI; Yamamoto J; Han Q; Sun YU; Nishino H; Tashiro Y; Sugisawa N; Tan Y; Choi HJ; Nam SJ; Bouvet M; Hoffman RM In Vivo; 2020; 34(6):3163-3169. PubMed ID: 33144420 [TBL] [Abstract][Full Text] [Related]
15. Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model. Higuchi T; Kawaguchi K; Miyake K; Han Q; Tan Y; Oshiro H; Sugisawa N; Zhang Z; Razmjooei S; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Chawla SP; Singh AS; Eilber FC; Singh SR; Tsuchiya H; Hoffman RM Anticancer Res; 2018 Oct; 38(10):5639-5644. PubMed ID: 30275182 [TBL] [Abstract][Full Text] [Related]
16. Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model. Miyake K; Kiyuna T; Li S; Han Q; Tan Y; Zhao M; Oshiro H; Kawaguchi K; Higuchi T; Zhang Z; Razmjooei S; Barangi M; Wangsiricharoen S; Murakami T; Singh AS; Li Y; Nelson SD; Eilber FC; Bouvet M; Hiroshima Y; Chishima T; Matsuyama R; Singh SR; Endo I; Hoffman RM Chemotherapy; 2018; 63(5):278-283. PubMed ID: 30673664 [TBL] [Abstract][Full Text] [Related]
17. Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase. Igarashi K; Li S; Han Q; Tan Y; Kawaguchi K; Murakami T; Kiyuna T; Miyake K; Li Y; Nelson SD; Dry SM; Singh AS; Elliott IA; Russell TA; Eckardt MA; Yamamoto N; Hayashi K; Kimura H; Miwa S; Tsuchiya H; Eilber FC; Hoffman RM J Cell Biochem; 2018 Apr; 119(4):3537-3544. PubMed ID: 29143983 [TBL] [Abstract][Full Text] [Related]
18. Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model. Higuchi T; Han Q; Miyake K; Oshiro H; Sugisawa N; Tan Y; Yamamoto N; Hayashi K; Kimura H; Miwa S; Igarashi K; Bouvet M; Singh SR; Tsuchiya H; Hoffman RM Biochem Biophys Res Commun; 2020 Feb; 523(1):135-139. PubMed ID: 31839218 [TBL] [Abstract][Full Text] [Related]
19. Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model. Park JH; Han Q; Zhao M; Tan Y; Higuchi T; Yoon SN; Sugisawa N; Yamamoto J; Bouvet M; Clary B; Singh SR; Hoffman RM Tissue Cell; 2019 Dec; 61():109-114. PubMed ID: 31759402 [TBL] [Abstract][Full Text] [Related]
20. Oral Methioninase Inhibits Recurrence in a PDOX Mouse Model of Aggressive Triple-negative Breast Cancer. Lim HI; Hamada K; Yamamoto J; Han Q; Tan Y; Choi HJ; Nam SJ; Bouvet M; Hoffman RM In Vivo; 2020; 34(5):2281-2286. PubMed ID: 32871751 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]