BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 36293224)

  • 1. Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers.
    Zhou X; Fu YH; Zou YY; Meng J; Ou-Yang GP; Ge QS; Wang ZC
    Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293224
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of facile amides-functionalized rhodanine-3-acetic acid derivatives as potential anticancer agents by disrupting microtubule dynamics.
    Zhou X; Liu J; Meng J; Fu Y; Wu Z; Ouyang G; Wang Z
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1996-2009. PubMed ID: 34525898
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure-activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study.
    Saruengkhanphasit R; Butkinaree C; Ornnork N; Lirdprapamongkol K; Niwetmarin W; Svasti J; Ruchirawat S; Eurtivong C
    Bioorg Chem; 2021 May; 110():104795. PubMed ID: 33730670
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
    Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of novel microtubule stabilizers targeting taxane binding site by applying molecular docking, molecular dynamics simulation, and anticancer activity testing.
    Zhang H; Qi HZ; Mao J; Zhang HR; Luo QQ; Hu ML; Shen C; Ding L
    Bioorg Chem; 2022 May; 122():105722. PubMed ID: 35303622
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
    Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y; Lin H; Ou C; Cao Y; An B; Yan J; Li X
    Eur J Med Chem; 2019 Nov; 182():111670. PubMed ID: 31499359
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.
    Song J; Wang SH; Song CH; Zhang WX; Zhu JX; Tian XY; Fu XJ; Xu Y; Jin CY; Zhang SY
    Eur J Med Chem; 2022 Oct; 240():114583. PubMed ID: 35834904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of microtubule stabilizers with novel scaffold structures based on virtual screening, biological evaluation, and molecular dynamics simulation.
    Mao J; Luo QQ; Zhang HR; Zheng XH; Shen C; Qi HZ; Hu ML; Zhang H
    Chem Biol Interact; 2022 Jan; 352():109784. PubMed ID: 34932952
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS; Tabeshpour J; Mirzaei S; Golmakaniyoon S; Tayarani-Najaran Z; Ghasemi A; Ghodsi R
    Arch Pharm (Weinheim); 2019 Jun; 352(6):e1800307. PubMed ID: 31012156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S; An B; Li Y; Luo X; Li X; Jia X
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1769-1775. PubMed ID: 29673981
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
    Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL
    Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker.
    Maklad RM; AbdelHafez EMN; Abdelhamid D; Aly OM
    Bioorg Chem; 2020 Jun; 99():103767. PubMed ID: 32325332
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F; Yu LZ; Diao PC; Jian XE; Zhou MF; Jiang CS; You WW; Ma WF; Zhao PL
    Bioorg Chem; 2019 Nov; 92():103260. PubMed ID: 31525523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R; Zhang S; Huang M; Guo Z; Li L; Li M; Wu L; Guan Q; Zhang W
    Bioorg Chem; 2021 Oct; 115():105220. PubMed ID: 34352709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.
    Ren Y; Ruan Y; Cheng B; Li L; Liu J; Fang Y; Chen J
    Bioorg Med Chem; 2021 Sep; 46():116376. PubMed ID: 34455231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D; Liu Y; Yan W; Wang C; Bai P; Wang T; Tang M; Wang X; Yang Z; Ma B; Ma L; Lei L; Wang F; Xu B; Zhou Y; Yang T; Chen L
    J Med Chem; 2016 Jun; 59(12):5721-39. PubMed ID: 27213819
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization.
    Wang SY; Liu X; Meng LW; Li MM; Li YR; Yu GX; Song J; Zhang HY; Chen P; Zhang SY; Hu T
    Bioorg Med Chem Lett; 2021 Jul; 43():128095. PubMed ID: 33965530
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of 2-aryl-1H-benzo[d]imidazole derivatives as potential microtubule targeting agents.
    Lee JS; Song IH; Warkad SD; Yeom GS; Shinde PB; Song KS; Nimse SB
    Drug Dev Res; 2022 May; 83(3):769-782. PubMed ID: 35038352
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.