BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 36310032)

  • 1. Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver.
    Ichida H; Fukami T; Amai K; Suzuki K; Mishiro K; Takano S; Obuchi W; Zhang Z; Watanabe A; Nakano M; Watanabe K; Nakajima M
    Drug Metab Dispos; 2023 Jan; 51(1):17-28. PubMed ID: 36310032
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quantitative Analysis of mRNA and Protein Expression Levels of Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoforms in the Human Intestine.
    Hirosawa K; Fujioka H; Morinaga G; Fukami T; Ishiguro N; Kishimoto W; Nakase H; Mizuguchi H; Nakajima M
    Drug Metab Dispos; 2023 Dec; 51(12):1569-1577. PubMed ID: 37722844
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantitative analysis of mRNA expression levels of aldo-keto reductase and short-chain dehydrogenase/reductase isoforms in human livers.
    Amai K; Fukami T; Ichida H; Watanabe A; Nakano M; Watanabe K; Nakajima M
    Drug Metab Pharmacokinet; 2020 Dec; 35(6):539-547. PubMed ID: 33036882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human dehydrogenase/reductase SDR family member 11 (DHRS11) and aldo-keto reductase 1C isoforms in comparison: Substrate and reaction specificity in the reduction of 11-keto-C
    Endo S; Morikawa Y; Kudo Y; Suenami K; Matsunaga T; Ikari A; Hara A
    J Steroid Biochem Mol Biol; 2020 May; 199():105586. PubMed ID: 31926269
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
    Penning TM; Burczynski ME; Jez JM; Hung CF; Lin HK; Ma H; Moore M; Palackal N; Ratnam K
    Biochem J; 2000 Oct; 351(Pt 1):67-77. PubMed ID: 10998348
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.
    Steckelbroeck S; Oyesanmi B; Jin Y; Lee SH; Kloosterboer HJ; Penning TM
    J Pharmacol Exp Ther; 2006 Mar; 316(3):1300-9. PubMed ID: 16339391
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sex hormones reduce NNK detoxification through inhibition of short-chain dehydrogenases/reductases and aldo-keto reductases in vitro.
    Stapelfeld C; Maser E
    Chem Biol Interact; 2017 Oct; 276():167-173. PubMed ID: 28257955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol.
    Atalla A; Breyer-Pfaff U; Maser E
    Xenobiotica; 2000 Aug; 30(8):755-69. PubMed ID: 11037109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Long-chain fatty acids inhibit human members of the aldo-keto reductase 1C subfamily.
    Hara A; Endo S; Matsunaga T; Soda M; Yashiro K; El-Kabbani O
    J Biochem; 2017 Nov; 162(5):371-379. PubMed ID: 28992312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Porcine aldo-keto reductase 1C subfamily members AKR1C1 and AKR1C4: Substrate specificity, inhibitor sensitivity and activators.
    Endo S; Morikawa Y; Matsunaga T; Hara A; Nishinaka T
    J Steroid Biochem Mol Biol; 2022 Jul; 221():106113. PubMed ID: 35398259
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid.
    Steckelbroeck S; Jin Y; Oyesanmi B; Kloosterboer HJ; Penning TM
    Mol Pharmacol; 2004 Dec; 66(6):1702-11. PubMed ID: 15383625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.
    Jin Y; Mesaros AC; Blair IA; Penning TM
    Biochem J; 2011 Jul; 437(1):53-61. PubMed ID: 21521174
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate.
    Lin HK; Steckelbroeck S; Fung KM; Jones AN; Penning TM
    Steroids; 2004 Dec; 69(13-14):795-801. PubMed ID: 15582534
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action.
    Steckelbroeck S; Jin Y; Gopishetty S; Oyesanmi B; Penning TM
    J Biol Chem; 2004 Mar; 279(11):10784-95. PubMed ID: 14672942
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.
    Palackal NT; Lee SH; Harvey RG; Blair IA; Penning TM
    J Biol Chem; 2002 Jul; 277(27):24799-808. PubMed ID: 11978787
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta.
    Atalla A; Maser E
    Chem Biol Interact; 2001 Jan; 130-132(1-3):737-48. PubMed ID: 11306090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man.
    Malátková P; Havlíková L; Wsól V
    Chem Biol Interact; 2014 Sep; 220():241-7. PubMed ID: 25063510
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.
    Hevir N; Vouk K; Sinkovec J; Ribič-Pucelj M; Rižner TL
    Chem Biol Interact; 2011 May; 191(1-3):217-26. PubMed ID: 21232532
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C3) in the extrahepatic metabolism of the steroidal aromatase inactivator Formestane.
    Wan R; Kong X; Yang Y; Tao S; Chen Y; Teichmann AT; Wieland FH
    J Steroid Biochem Mol Biol; 2020 Apr; 198():105527. PubMed ID: 31733346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members.
    O'connor T; Ireland LS; Harrison DJ; Hayes JD
    Biochem J; 1999 Oct; 343 Pt 2(Pt 2):487-504. PubMed ID: 10510318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.