BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 36322143)

  • 1. Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors.
    Ma L; Liang C; Wang J; Chang Q; Wang Y; Zhang W; Du Y; Sadan J; Chen JF
    Hum Mol Genet; 2023 Apr; 32(8):1252-1265. PubMed ID: 36322143
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
    Chew J; Cook C; Gendron TF; Jansen-West K; Del Rosso G; Daughrity LM; Castanedes-Casey M; Kurti A; Stankowski JN; Disney MD; Rothstein JD; Dickson DW; Fryer JD; Zhang YJ; Petrucelli L
    Mol Neurodegener; 2019 Feb; 14(1):9. PubMed ID: 30767771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models.
    Liang C; Shao Q; Zhang W; Yang M; Chang Q; Chen R; Chen JF
    Hum Mol Genet; 2019 Dec; 28(23):3940-3953. PubMed ID: 31625563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis.
    Trageser KJ; Yang EJ; Smith C; Iban-Arias R; Oguchi T; Sebastian-Valverde M; Iqbal UH; Wu H; Estill M; Al Rahim M; Raval U; Herman FJ; Zhang YJ; Petrucelli L; Pasinetti GM
    Mol Neurobiol; 2023 Jul; 60(7):4004-4016. PubMed ID: 37010807
    [TBL] [Abstract][Full Text] [Related]  

  • 7.
    Shao Q; Yang M; Liang C; Ma L; Zhang W; Jiang Z; Luo J; Lee JK; Liang C; Chen JF
    Autophagy; 2020 Sep; 16(9):1635-1650. PubMed ID: 31847700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.
    Esanov R; Cabrera GT; Andrade NS; Gendron TF; Brown RH; Benatar M; Wahlestedt C; Mueller C; Zeier Z
    Mol Neurodegener; 2017 Jun; 12(1):46. PubMed ID: 28606110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
    Ramesh N; Daley EL; Gleixner AM; Mann JR; Kour S; Mawrie D; Anderson EN; Kofler J; Donnelly CJ; Kiskinis E; Pandey UB
    Acta Neuropathol Commun; 2020 Oct; 8(1):177. PubMed ID: 33129345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
    Shi Y; Lin S; Staats KA; Li Y; Chang WH; Hung ST; Hendricks E; Linares GR; Wang Y; Son EY; Wen X; Kisler K; Wilkinson B; Menendez L; Sugawara T; Woolwine P; Huang M; Cowan MJ; Ge B; Koutsodendris N; Sandor KP; Komberg J; Vangoor VR; Senthilkumar K; Hennes V; Seah C; Nelson AR; Cheng TY; Lee SJ; August PR; Chen JA; Wisniewski N; Hanson-Smith V; Belgard TG; Zhang A; Coba M; Grunseich C; Ward ME; van den Berg LH; Pasterkamp RJ; Trotti D; Zlokovic BV; Ichida JK
    Nat Med; 2018 Mar; 24(3):313-325. PubMed ID: 29400714
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
    Boivin M; Pfister V; Gaucherot A; Ruffenach F; Negroni L; Sellier C; Charlet-Berguerand N
    EMBO J; 2020 Feb; 39(4):e100574. PubMed ID: 31930538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
    Odeh HM; Shorter J
    Emerg Top Life Sci; 2020 Dec; 4(3):293-305. PubMed ID: 32639008
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
    Lan Y; Sullivan PM; Hu F
    Autophagy; 2019 May; 15(5):871-885. PubMed ID: 30696333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cellular and physiological functions of C9ORF72 and implications for ALS/FTD.
    Pang W; Hu F
    J Neurochem; 2021 May; 157(3):334-350. PubMed ID: 33259633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72.
    Murray ME; DeJesus-Hernandez M; Rutherford NJ; Baker M; Duara R; Graff-Radford NR; Wszolek ZK; Ferman TJ; Josephs KA; Boylan KB; Rademakers R; Dickson DW
    Acta Neuropathol; 2011 Dec; 122(6):673-90. PubMed ID: 22083254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo.
    Todd TW; McEachin ZT; Chew J; Burch AR; Jansen-West K; Tong J; Yue M; Song Y; Castanedes-Casey M; Kurti A; Dunmore JH; Fryer JD; Zhang YJ; San Millan B; Teijeira Bautista S; Arias M; Dickson D; Gendron TF; Sobrido MJ; Disney MD; Bassell GJ; Rossoll W; Petrucelli L
    Cell Rep; 2020 May; 31(5):107616. PubMed ID: 32375043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G
    Czuppa M; Dhingra A; Zhou Q; Schludi C; König L; Scharf E; Farny D; Dalmia A; Täger J; Castillo-Lizardo M; Katona E; Mori K; Aumer T; Schelter F; Müller M; Carell T; Kalliokoski T; Messinger J; Rizzu P; Heutink P; Edbauer D
    Cell Rep; 2022 Jun; 39(10):110913. PubMed ID: 35675776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
    Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
    Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Systemic deregulation of autophagy upon loss of ALS- and FTD-linked C9orf72.
    Ji YJ; Ugolino J; Brady NR; Hamacher-Brady A; Wang J
    Autophagy; 2017 Jul; 13(7):1254-1255. PubMed ID: 28319438
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.