BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 36322662)

  • 1. Untangling the roles of TOP2A and TOP2B in transcription and cancer.
    Uusküla-Reimand L; Wilson MD
    Sci Adv; 2022 Nov; 8(44):eadd4920. PubMed ID: 36322662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs.
    Trinh BQ; Ko SY; Barengo N; Lin SY; Naora H
    Cancer Res; 2013 Jan; 73(2):1000-10. PubMed ID: 23222298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders.
    Uusküla-Reimand L; Hou H; Samavarchi-Tehrani P; Rudan MV; Liang M; Medina-Rivera A; Mohammed H; Schmidt D; Schwalie P; Young EJ; Reimand J; Hadjur S; Gingras AC; Wilson MD
    Genome Biol; 2016 Aug; 17(1):182. PubMed ID: 27582050
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
    Morimoto S; Tsuda M; Bunch H; Sasanuma H; Austin C; Takeda S
    Genes (Basel); 2019 Oct; 10(11):. PubMed ID: 31671674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
    Gothe HJ; Bouwman BAM; Gusmao EG; Piccinno R; Petrosino G; Sayols S; Drechsel O; Minneker V; Josipovic N; Mizi A; Nielsen CF; Wagner EM; Takeda S; Sasanuma H; Hudson DF; Kindler T; Baranello L; Papantonis A; Crosetto N; Roukos V
    Mol Cell; 2019 Jul; 75(2):267-283.e12. PubMed ID: 31202576
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
    Canela A; Maman Y; Huang SN; Wutz G; Tang W; Zagnoli-Vieira G; Callen E; Wong N; Day A; Peters JM; Caldecott KW; Pommier Y; Nussenzweig A
    Mol Cell; 2019 Jul; 75(2):252-266.e8. PubMed ID: 31202577
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.
    Gómez-Herreros F; Zagnoli-Vieira G; Ntai I; Martínez-Macías MI; Anderson RM; Herrero-Ruíz A; Caldecott KW
    Nat Commun; 2017 Aug; 8(1):233. PubMed ID: 28794467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of topoisomerase II stability and activity by ubiquitination and SUMOylation: clinical implications for cancer chemotherapy.
    Ma Y; North BJ; Shu J
    Mol Biol Rep; 2021 Sep; 48(9):6589-6601. PubMed ID: 34476738
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.
    Meyer-Ficca ML; Lonchar JD; Ihara M; Meistrich ML; Austin CA; Meyer RG
    Biol Reprod; 2011 May; 84(5):900-9. PubMed ID: 21228215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. To Break or Not to Break: The Role of TOP2B in Transcription.
    Cowell IG; Casement JW; Austin CA
    Int J Mol Sci; 2023 Sep; 24(19):. PubMed ID: 37834253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
    Gómez-Herreros F; Schuurs-Hoeijmakers JH; McCormack M; Greally MT; Rulten S; Romero-Granados R; Counihan TJ; Chaila E; Conroy J; Ennis S; Delanty N; Cortés-Ledesma F; de Brouwer AP; Cavalleri GL; El-Khamisy SF; de Vries BB; Caldecott KW
    Nat Genet; 2014 May; 46(5):516-21. PubMed ID: 24658003
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".
    Das SK; Kuzin V; Cameron DP; Sanford S; Jha RK; Nie Z; Rosello MT; Holewinski R; Andresson T; Wisniewski J; Natsume T; Price DH; Lewis BA; Kouzine F; Levens D; Baranello L
    Mol Cell; 2022 Jan; 82(1):140-158.e12. PubMed ID: 34890565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Replication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposide.
    Tammaro M; Barr P; Ricci B; Yan H
    PLoS One; 2013; 8(11):e79202. PubMed ID: 24244448
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity.
    Olmedo-Pelayo J; Rubio-Contreras D; Gómez-Herreros F
    Nucleic Acids Res; 2020 Sep; 48(16):9147-9160. PubMed ID: 32749454
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Topoisomerase 2β and DNA topology during B cell development.
    Papapietro O; Nejentsev S
    Front Immunol; 2022; 13():982870. PubMed ID: 36045673
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.
    Smith KA; Cowell IG; Zhang Y; Sondka Z; Austin CA
    Genes Chromosomes Cancer; 2014 Feb; 53(2):117-28. PubMed ID: 24327541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome Organization Drives Chromosome Fragility.
    Canela A; Maman Y; Jung S; Wong N; Callen E; Day A; Kieffer-Kwon KR; Pekowska A; Zhang H; Rao SSP; Huang SC; Mckinnon PJ; Aplan PD; Pommier Y; Aiden EL; Casellas R; Nussenzweig A
    Cell; 2017 Jul; 170(3):507-521.e18. PubMed ID: 28735753
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?
    Haffner MC; De Marzo AM; Meeker AK; Nelson WG; Yegnasubramanian S
    Clin Cancer Res; 2011 Jun; 17(12):3858-64. PubMed ID: 21385925
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.
    Yu X; Davenport JW; Urtishak KA; Carillo ML; Gosai SJ; Kolaris CP; Byl JAW; Rappaport EF; Osheroff N; Gregory BD; Felix CA
    Genome Res; 2017 Jul; 27(7):1238-1249. PubMed ID: 28385713
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural organization of the human TOP2A and TOP2B genes.
    Lang AJ; Mirski SE; Cummings HJ; Yu Q; Gerlach JH; Cole SP
    Gene; 1998 Oct; 221(2):255-66. PubMed ID: 9795238
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.