These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 36322830)

  • 1. Low-Molecular Weight Small Molecules Can Potently Bind RNA and Affect Oncogenic Pathways in Cells.
    Suresh BM; Akahori Y; Taghavi A; Crynen G; Gibaut QMR; Li Y; Disney MD
    J Am Chem Soc; 2022 Nov; 144(45):20815-20824. PubMed ID: 36322830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A general fragment-based approach to identify and optimize bioactive ligands targeting RNA.
    Suresh BM; Li W; Zhang P; Wang KW; Yildirim I; Parker CG; Disney MD
    Proc Natl Acad Sci U S A; 2020 Dec; 117(52):33197-33203. PubMed ID: 33318191
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer.
    Costales MG; Aikawa H; Li Y; Childs-Disney JL; Abegg D; Hoch DG; Pradeep Velagapudi S; Nakai Y; Khan T; Wang KW; Yildirim I; Adibekian A; Wang ET; Disney MD
    Proc Natl Acad Sci U S A; 2020 Feb; 117(5):2406-2411. PubMed ID: 31964809
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules.
    Vo DD; Staedel C; Zehnacker L; Benhida R; Darfeuille F; Duca M
    ACS Chem Biol; 2014 Mar; 9(3):711-21. PubMed ID: 24359019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions.
    Haniff HS; Knerr L; Liu X; Crynen G; Boström J; Abegg D; Adibekian A; Lekah E; Wang KW; Cameron MD; Yildirim I; Lemurell M; Disney MD
    Nat Chem; 2020 Oct; 12(10):952-961. PubMed ID: 32839603
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Speeding drug discovery targeting RNAs: An iterative "RNA selection-compounds screening cycle" for exploring RNA-small molecule pairs.
    Furuzono T; Murata A; Okuda S; Mizutani K; Adachi T; Nakatani K
    Bioorg Med Chem; 2021 Apr; 36():116070. PubMed ID: 33773376
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs.
    Velagapudi SP; Costales MG; Vummidi BR; Nakai Y; Angelbello AJ; Tran T; Haniff HS; Matsumoto Y; Wang ZF; Chatterjee AK; Childs-Disney JL; Disney MD
    Cell Chem Biol; 2018 Sep; 25(9):1086-1094.e7. PubMed ID: 30251629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor.
    Benhamou RI; Suresh BM; Tong Y; Cochrane WG; Cavett V; Vezina-Dawod S; Abegg D; Childs-Disney JL; Adibekian A; Paegel BM; Disney MD
    Proc Natl Acad Sci U S A; 2022 Feb; 119(6):. PubMed ID: 35110406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment.
    Zhang P; Liu X; Abegg D; Tanaka T; Tong Y; Benhamou RI; Baisden J; Crynen G; Meyer SM; Cameron MD; Chatterjee AK; Adibekian A; Childs-Disney JL; Disney MD
    J Am Chem Soc; 2021 Aug; 143(33):13044-13055. PubMed ID: 34387474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence.
    Disney MD; Angelbello AJ
    Acc Chem Res; 2016 Dec; 49(12):2698-2704. PubMed ID: 27993012
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design of a small molecule against an oncogenic noncoding RNA.
    Velagapudi SP; Cameron MD; Haga CL; Rosenberg LH; Lafitte M; Duckett DR; Phinney DG; Disney MD
    Proc Natl Acad Sci U S A; 2016 May; 113(21):5898-903. PubMed ID: 27170187
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How We Think about Targeting RNA with Small Molecules.
    Costales MG; Childs-Disney JL; Haniff HS; Disney MD
    J Med Chem; 2020 Sep; 63(17):8880-8900. PubMed ID: 32212706
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and implementation of an ribonucleic acid (RNA) directed fragment library.
    Bodoor K; Boyapati V; Gopu V; Boisdore M; Allam K; Miller J; Treleaven WD; Weldeghiorghis T; Aboul-ela F
    J Med Chem; 2009 Jun; 52(12):3753-61. PubMed ID: 19445516
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy.
    Rzuczek SG; Southern MR; Disney MD
    ACS Chem Biol; 2015 Dec; 10(12):2706-15. PubMed ID: 26414664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA.
    Ye F; Haniff HS; Suresh BM; Yang D; Zhang P; Crynen G; Teijaro CN; Yan W; Abegg D; Adibekian A; Shen B; Disney MD
    ACS Chem Biol; 2022 Feb; 17(2):474-482. PubMed ID: 35044149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit.
    Costales MG; Haga CL; Velagapudi SP; Childs-Disney JL; Phinney DG; Disney MD
    J Am Chem Soc; 2017 Mar; 139(9):3446-3455. PubMed ID: 28240549
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Innovations in targeting RNA by fragment-based ligand discovery.
    Koehn JT; Felder S; Weeks KM
    Curr Opin Struct Biol; 2023 Apr; 79():102550. PubMed ID: 36863268
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small Molecule Targeted Recruitment of a Nuclease to RNA.
    Costales MG; Matsumoto Y; Velagapudi SP; Disney MD
    J Am Chem Soc; 2018 Jun; 140(22):6741-6744. PubMed ID: 29792692
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing a 2-aminobenzimidazole library for binding to RNA internal loops via two-dimensional combinatorial screening.
    Velagapudi SP; Pushechnikov A; Labuda LP; French JM; Disney MD
    ACS Chem Biol; 2012 Nov; 7(11):1902-9. PubMed ID: 22958065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays.
    Connelly CM; Boer RE; Moon MH; Gareiss P; Schneekloth JS
    ACS Chem Biol; 2017 Feb; 12(2):435-443. PubMed ID: 27959491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.